TY  - JOUR
AU  - Ivošević, Tjasa
AU  - Miličić, Biljana
AU  - Dimitrijević, Milovan
AU  - Ivanović, Branislava
AU  - Pavlović, Aleksandar
AU  - Stojanović, Marina
AU  - Lakicević, Mirko
AU  - Stevanović, Ksenija
AU  - Kalezić, Nevena
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2307
AB  - Intraoperative bradycardia (IOB) is one of the most common cardiac arrhythmias observed in clinical anaesthetic practice. Controlled hypotension, as a strategy of lowering patient's blood pressure during anesthesia has been practiced for decades in head and neck surgery. The aim of our study was to determine the incidence and the risk factors for intraoperative bradycardia in maxillofacial, ear, nose and throat surgery, as well as to determine whether controlled hypotension affects the occurrence of IOB. The retrospective study included 2304 patients who underwent maxillofacial, ear, nose or throat surgery. We studied the influence of: sex, age, comorbidity, type of surgery, duration of anesthesia and controlled hypotension on the occurrence of IOB. IOB was registered in 473 patients (20.5%). Patients with controlled hypotension had IOB significantly more often than patients without controlled hypotension (33.9 vs 15.1%) (p = 0.000). The significant predictors of IOB were: age (OR = 1.158; 95% CI = 1.068-1.256; p = 0.000), sex (OR = 0.786; 95% CI = 0.623-0.993; p = 0.043), ischemic heart disease (OR = 2.016; 95% CI = 1.182-3.441; p = 0.010); ear surgery (OR = 1.593; 95% CI = 1.232-2.060; p = 0.000), anesthesia duration, (OR = 1.006; 95% CI = 1.004-1.007; p = 0.000) and controlled hypotension (OR = 2.204; 95% CI = 1.761-2.758; p = 0.000). IOB is common in maxillofacial, ear, nose and throat surgery, particularly in male, older age and patients with ishemic heart disease. The ear surgery, longer anesthesia duration and controlled hypotension raise the risk for occurrence of IOB.
PB  - Springer, New York
T2  - European Archives of Oto-Rhino-Laryngology
T1  - Risk factors for intraoperative bradycardia during ear, nose, throat and maxillofacial surgery
VL  - 275
IS  - 2
SP  - 579
EP  - 586
DO  - 10.1007/s00405-017-4837-8
ER  - 

@article{
author = "Ivošević, Tjasa and Miličić, Biljana and Dimitrijević, Milovan and Ivanović, Branislava and Pavlović, Aleksandar and Stojanović, Marina and Lakicević, Mirko and Stevanović, Ksenija and Kalezić, Nevena",
year = "2018",
abstract = "Intraoperative bradycardia (IOB) is one of the most common cardiac arrhythmias observed in clinical anaesthetic practice. Controlled hypotension, as a strategy of lowering patient's blood pressure during anesthesia has been practiced for decades in head and neck surgery. The aim of our study was to determine the incidence and the risk factors for intraoperative bradycardia in maxillofacial, ear, nose and throat surgery, as well as to determine whether controlled hypotension affects the occurrence of IOB. The retrospective study included 2304 patients who underwent maxillofacial, ear, nose or throat surgery. We studied the influence of: sex, age, comorbidity, type of surgery, duration of anesthesia and controlled hypotension on the occurrence of IOB. IOB was registered in 473 patients (20.5%). Patients with controlled hypotension had IOB significantly more often than patients without controlled hypotension (33.9 vs 15.1%) (p = 0.000). The significant predictors of IOB were: age (OR = 1.158; 95% CI = 1.068-1.256; p = 0.000), sex (OR = 0.786; 95% CI = 0.623-0.993; p = 0.043), ischemic heart disease (OR = 2.016; 95% CI = 1.182-3.441; p = 0.010); ear surgery (OR = 1.593; 95% CI = 1.232-2.060; p = 0.000), anesthesia duration, (OR = 1.006; 95% CI = 1.004-1.007; p = 0.000) and controlled hypotension (OR = 2.204; 95% CI = 1.761-2.758; p = 0.000). IOB is common in maxillofacial, ear, nose and throat surgery, particularly in male, older age and patients with ishemic heart disease. The ear surgery, longer anesthesia duration and controlled hypotension raise the risk for occurrence of IOB.",
publisher = "Springer, New York",
journal = "European Archives of Oto-Rhino-Laryngology",
title = "Risk factors for intraoperative bradycardia during ear, nose, throat and maxillofacial surgery",
volume = "275",
number = "2",
pages = "579-586",
doi = "10.1007/s00405-017-4837-8"
}

Ivošević, T., Miličić, B., Dimitrijević, M., Ivanović, B., Pavlović, A., Stojanović, M., Lakicević, M., Stevanović, K.,& Kalezić, N.. (2018). Risk factors for intraoperative bradycardia during ear, nose, throat and maxillofacial surgery. in European Archives of Oto-Rhino-Laryngology
Springer, New York., 275(2), 579-586.
https://doi.org/10.1007/s00405-017-4837-8

Ivošević T, Miličić B, Dimitrijević M, Ivanović B, Pavlović A, Stojanović M, Lakicević M, Stevanović K, Kalezić N. Risk factors for intraoperative bradycardia during ear, nose, throat and maxillofacial surgery. in European Archives of Oto-Rhino-Laryngology. 2018;275(2):579-586.
doi:10.1007/s00405-017-4837-8 .

Ivošević, Tjasa, Miličić, Biljana, Dimitrijević, Milovan, Ivanović, Branislava, Pavlović, Aleksandar, Stojanović, Marina, Lakicević, Mirko, Stevanović, Ksenija, Kalezić, Nevena, "Risk factors for intraoperative bradycardia during ear, nose, throat and maxillofacial surgery" in European Archives of Oto-Rhino-Laryngology, 275, no. 2 (2018):579-586,
https://doi.org/10.1007/s00405-017-4837-8 . .

TY  - JOUR
AU  - Stojanović, Marina
AU  - Kalezić, Nevena
AU  - Miličić, Biljana
AU  - Tosković, Anka R.
AU  - Stevanović, Ksenija
AU  - Antonijević, Vesna
AU  - Lakićević, Mirko
AU  - Bagi, Bojan
AU  - Živaljević, Vladan
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2328
AB  - Introduction/Objective Intraoperative variations in blood pressure and/or cardiac dysrhythmias (IOVBP/CD) represent one of the most common causes of morbidity and mortality in surgical patients. The aim of the study was to determine the incidence and risk factors for IOVBP/CD in thyroid surgery patients with comorbidities. Methods The study included 1,252 euthyroid patients with ASA 2 and ASA 3 status (American Society of Anesthesiologists - physical status classification) who underwent thyroid surgery. The following risk factors were examined: sex, age, body mass index (BMI), ASA status, admission diagnoses, type of operation, duration of surgery, time under general anesthesia, difficult intubation of trachea, and coexisting diseases - hypertension, cardiomyopathy, cardiac arrhythmias, angina pectoris, diabetes mellitus, kidney disease. The following intraoperative events were recorded: hypertension, severe hypertension, hypotension, and cardiac arrhythmias. We used Pearson χ2 square test, univariate, and multivariate logistic regression for statistical analysis. Results The majority of patients were female (86.3%). In 903 (72.1%) patients IOVBP/CD were detected. The most common problem was intraoperative hypertension (61.4%). Eight risk factors for IOVBP/CD were registered by univariate analysis: advanced age, ASA 3 status, BMI > 25 kg/m2, duration of surgery, time under general anesthesia, hypertension, and cardiomyopathy as a coexisting disease. The multivariate regression model identified three independent predictors for IOVBP/CD: age, hypertension, and cardiomyopathy. Conclusion IOVBP/CD are common in thyroid surgery. The most common is intraoperative hypertension. Older age, hypertension, and cardiomyopathy as a coexisting disease are independent risk factors for IOVBP/CD.
AB  - Uvod/Cilj Intraoperativne varijacije krvnog pritiska i/ ili srčane disritmije (IVKP/SD) jedan su od najčešćih uzročnika morbiditeta i mortaliteta hirurških bolesnika. Cilj studije je bio da ispita učestalost i faktore rizika za pojavu IVKP/SD u tireoidnoj hirurgiji kod bolesnika sa komorbiditetima. Metode Ispitivanje je obuhvatilo 1252 eutireoidna bolesnika ASA 2 i ASA 3 statusa podvrgnutih tireoidnoj hirurgiji. Ispitivan je uticaj sledećih faktora rizika: pol, starost, indeks telesne mase (ITM), ASA status, prijemna dijagnoza, tip operacije, trajanje operacije, trajanje anestezije, otežana intubacija traheje, kao i komorbiditeti: hipertenzija, kardiomiopatija, srčane aritmije, angina pektoris, dijabetes melitus, bolesti bubrega. Registrovani su intraoperativno: hipertenzija, hipertenzivna kriza, hipotenzija i srčane aritmije. Korišćen je Pirsonov χ2-test, univarijantna i multivarijantna regresiona analiza za statističku obradu podataka. Rezultati Većinu bolesnika su činile žene (86,3%). IVKP/ SD su registrovani kod 903 (72,1%) bolesnika. Najčešći poremećaj je bila intraoperativna hipertenzija - 61,4%. Univarijantnom analizom je registrovano sedam faktora rizika za pojavu IVKP/SD: godine života, ASA 3 status, ITM > 25 kg/m2, trajanje hirurgije, trajanje anestezije, hipertenzija i kardiomiopatija kao komorbiditet. Multivarijantnom regresionom analizom izdvojila su se tri nezavisna prediktora pojave IVKP/SD: godine starosti, hipertenzija i kardiomiopatija. Zaključak IVKP/SD su česte u tireoidnoj hirurgiji. Najčešća je intraoperativna hipertenzija. Starije životno doba, hipertenzija i kardiomiopatija kao koegzistirajuće bolesti su nezavisni faktori rizika za pojavu IVKP/SD.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery
T1  - Faktori rizika za pojavu intraoperativnih varijacija vrednosti krvnog pritiska i srčanih disritmija tokom tireoidne hirurgije
VL  - 146
IS  - 3-4
SP  - 163
EP  - 168
DO  - 10.2298/SARH170522156S
ER  - 

@article{
author = "Stojanović, Marina and Kalezić, Nevena and Miličić, Biljana and Tosković, Anka R. and Stevanović, Ksenija and Antonijević, Vesna and Lakićević, Mirko and Bagi, Bojan and Živaljević, Vladan",
year = "2018",
abstract = "Introduction/Objective Intraoperative variations in blood pressure and/or cardiac dysrhythmias (IOVBP/CD) represent one of the most common causes of morbidity and mortality in surgical patients. The aim of the study was to determine the incidence and risk factors for IOVBP/CD in thyroid surgery patients with comorbidities. Methods The study included 1,252 euthyroid patients with ASA 2 and ASA 3 status (American Society of Anesthesiologists - physical status classification) who underwent thyroid surgery. The following risk factors were examined: sex, age, body mass index (BMI), ASA status, admission diagnoses, type of operation, duration of surgery, time under general anesthesia, difficult intubation of trachea, and coexisting diseases - hypertension, cardiomyopathy, cardiac arrhythmias, angina pectoris, diabetes mellitus, kidney disease. The following intraoperative events were recorded: hypertension, severe hypertension, hypotension, and cardiac arrhythmias. We used Pearson χ2 square test, univariate, and multivariate logistic regression for statistical analysis. Results The majority of patients were female (86.3%). In 903 (72.1%) patients IOVBP/CD were detected. The most common problem was intraoperative hypertension (61.4%). Eight risk factors for IOVBP/CD were registered by univariate analysis: advanced age, ASA 3 status, BMI > 25 kg/m2, duration of surgery, time under general anesthesia, hypertension, and cardiomyopathy as a coexisting disease. The multivariate regression model identified three independent predictors for IOVBP/CD: age, hypertension, and cardiomyopathy. Conclusion IOVBP/CD are common in thyroid surgery. The most common is intraoperative hypertension. Older age, hypertension, and cardiomyopathy as a coexisting disease are independent risk factors for IOVBP/CD., Uvod/Cilj Intraoperativne varijacije krvnog pritiska i/ ili srčane disritmije (IVKP/SD) jedan su od najčešćih uzročnika morbiditeta i mortaliteta hirurških bolesnika. Cilj studije je bio da ispita učestalost i faktore rizika za pojavu IVKP/SD u tireoidnoj hirurgiji kod bolesnika sa komorbiditetima. Metode Ispitivanje je obuhvatilo 1252 eutireoidna bolesnika ASA 2 i ASA 3 statusa podvrgnutih tireoidnoj hirurgiji. Ispitivan je uticaj sledećih faktora rizika: pol, starost, indeks telesne mase (ITM), ASA status, prijemna dijagnoza, tip operacije, trajanje operacije, trajanje anestezije, otežana intubacija traheje, kao i komorbiditeti: hipertenzija, kardiomiopatija, srčane aritmije, angina pektoris, dijabetes melitus, bolesti bubrega. Registrovani su intraoperativno: hipertenzija, hipertenzivna kriza, hipotenzija i srčane aritmije. Korišćen je Pirsonov χ2-test, univarijantna i multivarijantna regresiona analiza za statističku obradu podataka. Rezultati Većinu bolesnika su činile žene (86,3%). IVKP/ SD su registrovani kod 903 (72,1%) bolesnika. Najčešći poremećaj je bila intraoperativna hipertenzija - 61,4%. Univarijantnom analizom je registrovano sedam faktora rizika za pojavu IVKP/SD: godine života, ASA 3 status, ITM > 25 kg/m2, trajanje hirurgije, trajanje anestezije, hipertenzija i kardiomiopatija kao komorbiditet. Multivarijantnom regresionom analizom izdvojila su se tri nezavisna prediktora pojave IVKP/SD: godine starosti, hipertenzija i kardiomiopatija. Zaključak IVKP/SD su česte u tireoidnoj hirurgiji. Najčešća je intraoperativna hipertenzija. Starije životno doba, hipertenzija i kardiomiopatija kao koegzistirajuće bolesti su nezavisni faktori rizika za pojavu IVKP/SD.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery, Faktori rizika za pojavu intraoperativnih varijacija vrednosti krvnog pritiska i srčanih disritmija tokom tireoidne hirurgije",
volume = "146",
number = "3-4",
pages = "163-168",
doi = "10.2298/SARH170522156S"
}

Stojanović, M., Kalezić, N., Miličić, B., Tosković, A. R., Stevanović, K., Antonijević, V., Lakićević, M., Bagi, B.,& Živaljević, V.. (2018). Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 146(3-4), 163-168.
https://doi.org/10.2298/SARH170522156S

Stojanović M, Kalezić N, Miličić B, Tosković AR, Stevanović K, Antonijević V, Lakićević M, Bagi B, Živaljević V. Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery. in Srpski arhiv za celokupno lekarstvo. 2018;146(3-4):163-168.
doi:10.2298/SARH170522156S .

Stojanović, Marina, Kalezić, Nevena, Miličić, Biljana, Tosković, Anka R., Stevanović, Ksenija, Antonijević, Vesna, Lakićević, Mirko, Bagi, Bojan, Živaljević, Vladan, "Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery" in Srpski arhiv za celokupno lekarstvo, 146, no. 3-4 (2018):163-168,
https://doi.org/10.2298/SARH170522156S . .

TY  - JOUR
AU  - Cvetković, Ana
AU  - Kalezić, Nevena
AU  - Miličić, Biljana
AU  - Nikolić, Srđan
AU  - Zegarac, Milan
AU  - Stojiljković, Dejan
AU  - Goran, Merima
AU  - Stojanović, Marina
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2285
AB  - Purpose: To determine whether there was a correlation between the type of administered infusion solutions intraoperatively with the quantity of administered infusion solutions, differences in values of cardiac output (CO) and cardiac index (CI) and need to use vasopressors and inotropes, between control and research groups. Methods: This randomized prospective study included 55 patients with colorectal cancer. Subjects in the control group received only crystalloid solutions intraoperatively and postoperatively. The patients in the research group received a combination of colloid in dosage of 10mg/kg and crystalloid solutions. Patients in both groups were given goal directed fluid therapy. Results: The control group received a significantly larger amount of crystalloid solution per kg of body weight during the entire surgical operation, in comparison with the volume of crystalloids in the research group (mean +/- SD 50.78 +/- 28.13 vs. 31.63 +/- 25.60 respectively, p=0.01). During the first hour of the surgery, the control group received a larger quantity of fluid in comparison with the research group (mean +/- SD 31.14 +/- 9.78 vs. 22.17 +/- 9.92 respectively, p=0.001). From the beginning of anesthesia until 6th postoperative hr the values of CI were significantly higher in the research group in comparison with the control group. Conclusions: Goal directed fluid therapy with colloids, followed by crystalloids during surgery, decreased the total intraoperative fluid volumes, and provided higher values of CI intraoperatively which were also maintained postoperatively.
PB  - Balkan Union of Oncology (B.U.ON.)
T2  - Journal of BUON
T1  - Hemodynamic stability achievement by application of goal directed fluid therapy with different infusion solutions in colorectal surgery
VL  - 23
IS  - 2
SP  - 329
EP  - 339
UR  - https://hdl.handle.net/21.15107/rcub_smile_2285
ER  - 

@article{
author = "Cvetković, Ana and Kalezić, Nevena and Miličić, Biljana and Nikolić, Srđan and Zegarac, Milan and Stojiljković, Dejan and Goran, Merima and Stojanović, Marina",
year = "2018",
abstract = "Purpose: To determine whether there was a correlation between the type of administered infusion solutions intraoperatively with the quantity of administered infusion solutions, differences in values of cardiac output (CO) and cardiac index (CI) and need to use vasopressors and inotropes, between control and research groups. Methods: This randomized prospective study included 55 patients with colorectal cancer. Subjects in the control group received only crystalloid solutions intraoperatively and postoperatively. The patients in the research group received a combination of colloid in dosage of 10mg/kg and crystalloid solutions. Patients in both groups were given goal directed fluid therapy. Results: The control group received a significantly larger amount of crystalloid solution per kg of body weight during the entire surgical operation, in comparison with the volume of crystalloids in the research group (mean +/- SD 50.78 +/- 28.13 vs. 31.63 +/- 25.60 respectively, p=0.01). During the first hour of the surgery, the control group received a larger quantity of fluid in comparison with the research group (mean +/- SD 31.14 +/- 9.78 vs. 22.17 +/- 9.92 respectively, p=0.001). From the beginning of anesthesia until 6th postoperative hr the values of CI were significantly higher in the research group in comparison with the control group. Conclusions: Goal directed fluid therapy with colloids, followed by crystalloids during surgery, decreased the total intraoperative fluid volumes, and provided higher values of CI intraoperatively which were also maintained postoperatively.",
publisher = "Balkan Union of Oncology (B.U.ON.)",
journal = "Journal of BUON",
title = "Hemodynamic stability achievement by application of goal directed fluid therapy with different infusion solutions in colorectal surgery",
volume = "23",
number = "2",
pages = "329-339",
url = "https://hdl.handle.net/21.15107/rcub_smile_2285"
}

Cvetković, A., Kalezić, N., Miličić, B., Nikolić, S., Zegarac, M., Stojiljković, D., Goran, M.,& Stojanović, M.. (2018). Hemodynamic stability achievement by application of goal directed fluid therapy with different infusion solutions in colorectal surgery. in Journal of BUON
Balkan Union of Oncology (B.U.ON.)., 23(2), 329-339.
https://hdl.handle.net/21.15107/rcub_smile_2285

Cvetković A, Kalezić N, Miličić B, Nikolić S, Zegarac M, Stojiljković D, Goran M, Stojanović M. Hemodynamic stability achievement by application of goal directed fluid therapy with different infusion solutions in colorectal surgery. in Journal of BUON. 2018;23(2):329-339.
https://hdl.handle.net/21.15107/rcub_smile_2285 .

Cvetković, Ana, Kalezić, Nevena, Miličić, Biljana, Nikolić, Srđan, Zegarac, Milan, Stojiljković, Dejan, Goran, Merima, Stojanović, Marina, "Hemodynamic stability achievement by application of goal directed fluid therapy with different infusion solutions in colorectal surgery" in Journal of BUON, 23, no. 2 (2018):329-339,
https://hdl.handle.net/21.15107/rcub_smile_2285 .

TY  - JOUR
AU  - Sabljak, Vera
AU  - Živaljević, Vladan
AU  - Miličić, Biljana
AU  - Paunović, Ivan
AU  - Tosković, Anka R.
AU  - Stevanović, Ksenija
AU  - Taušanović, Katarina
AU  - Marković, Dejan Z.
AU  - Stojanović, Marina
AU  - Lakićević, Mirko
AU  - Jovanović, Milan D.
AU  - Diklić, Aleksandar
AU  - Kalezić, Nevena
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2220
AB  - Objective: To investigate the incidence and identify risk factors for the occurrence of intraoperative hypertension (IOH) during surgery for primary hyperparathyroidism (pHPT). Subjects and Methods: The study included 269 patients surgically treated between January 2008 and January 2012 for pHPT. IOH was defined as an increase in systolic blood pressure >= 20% compared to baseline values which lasted for 15min. The investigated influence were demographic characteristics, surgical risk score related to physical status (based on the American Society of Anesthesiologists [ASA] classification), comorbidities, type and duration of surgery, and duration of anesthesia on IOH occurrence. The investigated factors were obtained from the patients' medical history, anesthesia charts, and the daily practice database. Logistic regression analysis was done to determine the predictors of IOH. Results: Of the 269 patients, 153 (56.9%) had IOH. Based on the univariate analysis, age, body mass index, ASA status, duration of anesthesia, and preoperative hypertension were risk factors for the occurrence of IOH. Multivariate analysis showed that independent predictors of IOH were a history of hypertension (OR = 2.080, 95% CI: 1.102-3.925, p = 0.024) and age (OR = 0.569, 95% CI: 0.360-0.901, p = 0.016). Conclusion: In this study, a high percentage (56%) of the patients developed IOH during surgery for pHPT, which indicates that special attention should be paid to these patients, especially to the high-risk groups: older patients and those with a history of hypertension. Further, this study showed that advanced age and hypertension as a coexisting disease prior to parathyroid surgery were independent risk factors for the occurrence of IOH.
PB  - Karger, Basel
T2  - Medical Principles & Practice
T1  - Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism
VL  - 26
IS  - 4
SP  - 381
EP  - 386
DO  - 10.1159/000475597
ER  - 

@article{
author = "Sabljak, Vera and Živaljević, Vladan and Miličić, Biljana and Paunović, Ivan and Tosković, Anka R. and Stevanović, Ksenija and Taušanović, Katarina and Marković, Dejan Z. and Stojanović, Marina and Lakićević, Mirko and Jovanović, Milan D. and Diklić, Aleksandar and Kalezić, Nevena",
year = "2017",
abstract = "Objective: To investigate the incidence and identify risk factors for the occurrence of intraoperative hypertension (IOH) during surgery for primary hyperparathyroidism (pHPT). Subjects and Methods: The study included 269 patients surgically treated between January 2008 and January 2012 for pHPT. IOH was defined as an increase in systolic blood pressure >= 20% compared to baseline values which lasted for 15min. The investigated influence were demographic characteristics, surgical risk score related to physical status (based on the American Society of Anesthesiologists [ASA] classification), comorbidities, type and duration of surgery, and duration of anesthesia on IOH occurrence. The investigated factors were obtained from the patients' medical history, anesthesia charts, and the daily practice database. Logistic regression analysis was done to determine the predictors of IOH. Results: Of the 269 patients, 153 (56.9%) had IOH. Based on the univariate analysis, age, body mass index, ASA status, duration of anesthesia, and preoperative hypertension were risk factors for the occurrence of IOH. Multivariate analysis showed that independent predictors of IOH were a history of hypertension (OR = 2.080, 95% CI: 1.102-3.925, p = 0.024) and age (OR = 0.569, 95% CI: 0.360-0.901, p = 0.016). Conclusion: In this study, a high percentage (56%) of the patients developed IOH during surgery for pHPT, which indicates that special attention should be paid to these patients, especially to the high-risk groups: older patients and those with a history of hypertension. Further, this study showed that advanced age and hypertension as a coexisting disease prior to parathyroid surgery were independent risk factors for the occurrence of IOH.",
publisher = "Karger, Basel",
journal = "Medical Principles & Practice",
title = "Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism",
volume = "26",
number = "4",
pages = "381-386",
doi = "10.1159/000475597"
}

Sabljak, V., Živaljević, V., Miličić, B., Paunović, I., Tosković, A. R., Stevanović, K., Taušanović, K., Marković, D. Z., Stojanović, M., Lakićević, M., Jovanović, M. D., Diklić, A.,& Kalezić, N.. (2017). Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism. in Medical Principles & Practice
Karger, Basel., 26(4), 381-386.
https://doi.org/10.1159/000475597

Sabljak V, Živaljević V, Miličić B, Paunović I, Tosković AR, Stevanović K, Taušanović K, Marković DZ, Stojanović M, Lakićević M, Jovanović MD, Diklić A, Kalezić N. Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism. in Medical Principles & Practice. 2017;26(4):381-386.
doi:10.1159/000475597 .

Sabljak, Vera, Živaljević, Vladan, Miličić, Biljana, Paunović, Ivan, Tosković, Anka R., Stevanović, Ksenija, Taušanović, Katarina, Marković, Dejan Z., Stojanović, Marina, Lakićević, Mirko, Jovanović, Milan D., Diklić, Aleksandar, Kalezić, Nevena, "Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism" in Medical Principles & Practice, 26, no. 4 (2017):381-386,
https://doi.org/10.1159/000475597 . .

TY  - JOUR
AU  - Vasiljević, Slađana
AU  - Miličić, Biljana
AU  - Sabljak, Vera
AU  - Jozić, Irena
AU  - Stojanović, Marina
AU  - Marković, Dejan
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1941
AB  - Background. Procedural sedation is a technique of administering sedatives or dissociative agents with or without analgesics to induce a state of consciousness that allows the patient to tolerate unpleasant procedures while maintaining cardiorespiratory function. Short-acting sedatives, anesthetics and analgesics along with non-invasive monitoring enable safely performing of this technique in a variety of hospital settings and early discharge two hours after procedure. Case report. We present a technique of procedural sedation and analgesia in the outpatient setting for performing esophagogastroduodenoscopy in patient with terminal renal insufficiency who was on dialysis and liver cirrhosis. Conclusion. Procedural sedation and analgesia for esophagogastroduodenoscopy can be safely performed by a combination of fentanyl and propofol, which enables its use in patients with impaired renal and hepatic function. Careful titration of propofol provides a moderate level of sedation and safe and efficient procedure performing.
AB  - Uvod. Proceduralna sedacija predstavlja tehniku primene sedativa i disocijativnih lekova, sa ili bez analgetika, u cilju promene stanja svesti koje bolesniku omogućava da toleriše neprijatne procedure, a da se pri tome ne narušava kardiorespiratorna funkcija. Za izvođenje ove vrste sedacije koriste se sedativi, analgetici i anestetici sa kratkim delovanjem, što uz neinvazivni monitoring, omogućava njeno bezbedno izvođenje u različitim bolničkim uslovima i rani otpust bolesnika, dva sata nakon procedure. Prikaz slučaja. U radu je prikazana tehnika proceduralne sedacije i analgezije u ambulantnim uslovima za izvođenje ezofagogastroduodenoskopije kod bolesnika sa terminalnom bubrežnom insuficijencijom koji je na programu dijalize i cirozom jetre. Zaključak. Proceduralna sedacija i analgezija za ezofagogastroduodenoskopiju se bezbedno izvodi kombinacijom fentanila i propofola, što omogućava njenu primenu i kod bolesnika sa umanjenom funkcijom jetre i bubrega. Pažljiva titracija propofola obezbeđuje umeren nivo sedacije i bezbedno i efikasno izvođenje procedure.
PB  - Udruženje anesteziologa i intenzivista Srbije, Beograd
T2  - Serbian Journal of Anesthesia & Intensive Therapy
T1  - Procedural sedation and analgesia in outpatient with altered liver and renal function
T1  - Proceduralna sedacija i analgezija u ambulantnim uslovima kod bolesnika sa narušenom funkcijom jetre i bubrega
VL  - 36
IS  - 3-4
SP  - 253
EP  - 259
UR  - https://hdl.handle.net/21.15107/rcub_smile_1941
ER  - 

@article{
author = "Vasiljević, Slađana and Miličić, Biljana and Sabljak, Vera and Jozić, Irena and Stojanović, Marina and Marković, Dejan",
year = "2014",
abstract = "Background. Procedural sedation is a technique of administering sedatives or dissociative agents with or without analgesics to induce a state of consciousness that allows the patient to tolerate unpleasant procedures while maintaining cardiorespiratory function. Short-acting sedatives, anesthetics and analgesics along with non-invasive monitoring enable safely performing of this technique in a variety of hospital settings and early discharge two hours after procedure. Case report. We present a technique of procedural sedation and analgesia in the outpatient setting for performing esophagogastroduodenoscopy in patient with terminal renal insufficiency who was on dialysis and liver cirrhosis. Conclusion. Procedural sedation and analgesia for esophagogastroduodenoscopy can be safely performed by a combination of fentanyl and propofol, which enables its use in patients with impaired renal and hepatic function. Careful titration of propofol provides a moderate level of sedation and safe and efficient procedure performing., Uvod. Proceduralna sedacija predstavlja tehniku primene sedativa i disocijativnih lekova, sa ili bez analgetika, u cilju promene stanja svesti koje bolesniku omogućava da toleriše neprijatne procedure, a da se pri tome ne narušava kardiorespiratorna funkcija. Za izvođenje ove vrste sedacije koriste se sedativi, analgetici i anestetici sa kratkim delovanjem, što uz neinvazivni monitoring, omogućava njeno bezbedno izvođenje u različitim bolničkim uslovima i rani otpust bolesnika, dva sata nakon procedure. Prikaz slučaja. U radu je prikazana tehnika proceduralne sedacije i analgezije u ambulantnim uslovima za izvođenje ezofagogastroduodenoskopije kod bolesnika sa terminalnom bubrežnom insuficijencijom koji je na programu dijalize i cirozom jetre. Zaključak. Proceduralna sedacija i analgezija za ezofagogastroduodenoskopiju se bezbedno izvodi kombinacijom fentanila i propofola, što omogućava njenu primenu i kod bolesnika sa umanjenom funkcijom jetre i bubrega. Pažljiva titracija propofola obezbeđuje umeren nivo sedacije i bezbedno i efikasno izvođenje procedure.",
publisher = "Udruženje anesteziologa i intenzivista Srbije, Beograd",
journal = "Serbian Journal of Anesthesia & Intensive Therapy",
title = "Procedural sedation and analgesia in outpatient with altered liver and renal function, Proceduralna sedacija i analgezija u ambulantnim uslovima kod bolesnika sa narušenom funkcijom jetre i bubrega",
volume = "36",
number = "3-4",
pages = "253-259",
url = "https://hdl.handle.net/21.15107/rcub_smile_1941"
}

Vasiljević, S., Miličić, B., Sabljak, V., Jozić, I., Stojanović, M.,& Marković, D.. (2014). Procedural sedation and analgesia in outpatient with altered liver and renal function. in Serbian Journal of Anesthesia & Intensive Therapy
Udruženje anesteziologa i intenzivista Srbije, Beograd., 36(3-4), 253-259.
https://hdl.handle.net/21.15107/rcub_smile_1941

Vasiljević S, Miličić B, Sabljak V, Jozić I, Stojanović M, Marković D. Procedural sedation and analgesia in outpatient with altered liver and renal function. in Serbian Journal of Anesthesia & Intensive Therapy. 2014;36(3-4):253-259.
https://hdl.handle.net/21.15107/rcub_smile_1941 .

Vasiljević, Slađana, Miličić, Biljana, Sabljak, Vera, Jozić, Irena, Stojanović, Marina, Marković, Dejan, "Procedural sedation and analgesia in outpatient with altered liver and renal function" in Serbian Journal of Anesthesia & Intensive Therapy, 36, no. 3-4 (2014):253-259,
https://hdl.handle.net/21.15107/rcub_smile_1941 .

TY  - JOUR
AU  - Kalezić, Nevena
AU  - Stojanović, Marina
AU  - Miličić, Biljana
AU  - Antonijević, Vesna
AU  - Sabljak, Vera
AU  - Marković, Dejan
AU  - Živaljević, Vladan
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1851
AB  - We studied the influence of demographic characteristics, comorbidity, and type and duration of surgery and anesthesia on the occurrence of intraoperative hypertension (IOHTA). Logistic regression analyses were used in order to determine the predictors of occurrence of IOHTA. More than 60% of our patients had IOHTA. Multivariate analysis showed that independent predictors for IOHTA were older age, BMI > 25 kg/m(2), and hypertension as a coexisting disease. Hypertension is common during thyroid surgery, and a significant number of patients remained hypertensive during the postoperative period.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Clinical & Experimental Hypertension
T1  - The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery
VL  - 35
IS  - 7
SP  - 523
EP  - 527
DO  - 10.3109/10641963.2012.758735
ER  - 

@article{
author = "Kalezić, Nevena and Stojanović, Marina and Miličić, Biljana and Antonijević, Vesna and Sabljak, Vera and Marković, Dejan and Živaljević, Vladan",
year = "2013",
abstract = "We studied the influence of demographic characteristics, comorbidity, and type and duration of surgery and anesthesia on the occurrence of intraoperative hypertension (IOHTA). Logistic regression analyses were used in order to determine the predictors of occurrence of IOHTA. More than 60% of our patients had IOHTA. Multivariate analysis showed that independent predictors for IOHTA were older age, BMI > 25 kg/m(2), and hypertension as a coexisting disease. Hypertension is common during thyroid surgery, and a significant number of patients remained hypertensive during the postoperative period.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Clinical & Experimental Hypertension",
title = "The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery",
volume = "35",
number = "7",
pages = "523-527",
doi = "10.3109/10641963.2012.758735"
}

Kalezić, N., Stojanović, M., Miličić, B., Antonijević, V., Sabljak, V., Marković, D.,& Živaljević, V.. (2013). The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery. in Clinical & Experimental Hypertension
Taylor & Francis Inc, Philadelphia., 35(7), 523-527.
https://doi.org/10.3109/10641963.2012.758735

Kalezić N, Stojanović M, Miličić B, Antonijević V, Sabljak V, Marković D, Živaljević V. The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery. in Clinical & Experimental Hypertension. 2013;35(7):523-527.
doi:10.3109/10641963.2012.758735 .

Kalezić, Nevena, Stojanović, Marina, Miličić, Biljana, Antonijević, Vesna, Sabljak, Vera, Marković, Dejan, Živaljević, Vladan, "The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery" in Clinical & Experimental Hypertension, 35, no. 7 (2013):523-527,
https://doi.org/10.3109/10641963.2012.758735 . .