TY  - JOUR
AU  - Dragašević, Sanja
AU  - Sokić-Milutinović, Aleksandra
AU  - Stojković-Lalošević, Milica
AU  - Milovanović, Tamara
AU  - Đuranović, Srđan
AU  - Jovanović, Ivan
AU  - Rajić, Sanja
AU  - Stojković, Mirjana
AU  - Miličić, Biljana
AU  - Kmezić, Stefan
AU  - Oluić, Branislav
AU  - Aleksić, Marko
AU  - Pavlović-Marković, Aleksandra
AU  - Popović, Dragan
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2507
AB  - Background and Objectives. Determination of inflammatory bowel disease activity determines further therapeutic approach and follow-up. The aim of our study was to investigate correlation between patients' reported symptoms and endoscopic and histological disease activity. Methods. A cross-sectional study was conducted in consecutive newly diagnosed patients with inflammatory bowel disease in a tertiary care referral center. The initial evaluation included patient-reported outcome for stool frequency subscore and rectal bleeding. Endoscopic activity was determined using the Mayo scoring system for ulcerative colitis and the Simple Endoscopic Score for Crohn's disease. Histopathological activity was assessed using a validated numeric scoring system. Results. We included 159 patients (63 Crohn's disease with colonic involvement and 96 with ulcerative colitis). We found significant correlation between the Mayo endoscopic subscoring system and histology activity in ulcerative colitis, while no correlation was found in patients with Crohn's disease. Patient-reported outcome showed inverse correlation with endoscopic and histological activity in Crohn's disease (rs=-0.67; rs=-0.72), while positive correlation was found in ulcerative colitis (rs=0.84; rs=0.75). Interpretation and Conclusions. Patient-reported outcome is a practical and noninvasive tool for assessment of disease activity in ulcerative colitis patients but not in Crohn's disease.
PB  - Hindawi Ltd, London
T2  - Gastroenterology Research & Practice
T1  - Correlation of Patient-Reported Outcome (PRO-2) with Endoscopic and Histological Features in Ulcerative Colitis and Crohn's Disease Patients
VL  - 2020
DO  - 10.1155/2020/2065383
ER  - 

@article{
author = "Dragašević, Sanja and Sokić-Milutinović, Aleksandra and Stojković-Lalošević, Milica and Milovanović, Tamara and Đuranović, Srđan and Jovanović, Ivan and Rajić, Sanja and Stojković, Mirjana and Miličić, Biljana and Kmezić, Stefan and Oluić, Branislav and Aleksić, Marko and Pavlović-Marković, Aleksandra and Popović, Dragan",
year = "2020",
abstract = "Background and Objectives. Determination of inflammatory bowel disease activity determines further therapeutic approach and follow-up. The aim of our study was to investigate correlation between patients' reported symptoms and endoscopic and histological disease activity. Methods. A cross-sectional study was conducted in consecutive newly diagnosed patients with inflammatory bowel disease in a tertiary care referral center. The initial evaluation included patient-reported outcome for stool frequency subscore and rectal bleeding. Endoscopic activity was determined using the Mayo scoring system for ulcerative colitis and the Simple Endoscopic Score for Crohn's disease. Histopathological activity was assessed using a validated numeric scoring system. Results. We included 159 patients (63 Crohn's disease with colonic involvement and 96 with ulcerative colitis). We found significant correlation between the Mayo endoscopic subscoring system and histology activity in ulcerative colitis, while no correlation was found in patients with Crohn's disease. Patient-reported outcome showed inverse correlation with endoscopic and histological activity in Crohn's disease (rs=-0.67; rs=-0.72), while positive correlation was found in ulcerative colitis (rs=0.84; rs=0.75). Interpretation and Conclusions. Patient-reported outcome is a practical and noninvasive tool for assessment of disease activity in ulcerative colitis patients but not in Crohn's disease.",
publisher = "Hindawi Ltd, London",
journal = "Gastroenterology Research & Practice",
title = "Correlation of Patient-Reported Outcome (PRO-2) with Endoscopic and Histological Features in Ulcerative Colitis and Crohn's Disease Patients",
volume = "2020",
doi = "10.1155/2020/2065383"
}

Dragašević, S., Sokić-Milutinović, A., Stojković-Lalošević, M., Milovanović, T., Đuranović, S., Jovanović, I., Rajić, S., Stojković, M., Miličić, B., Kmezić, S., Oluić, B., Aleksić, M., Pavlović-Marković, A.,& Popović, D.. (2020). Correlation of Patient-Reported Outcome (PRO-2) with Endoscopic and Histological Features in Ulcerative Colitis and Crohn's Disease Patients. in Gastroenterology Research & Practice
Hindawi Ltd, London., 2020.
https://doi.org/10.1155/2020/2065383

Dragašević S, Sokić-Milutinović A, Stojković-Lalošević M, Milovanović T, Đuranović S, Jovanović I, Rajić S, Stojković M, Miličić B, Kmezić S, Oluić B, Aleksić M, Pavlović-Marković A, Popović D. Correlation of Patient-Reported Outcome (PRO-2) with Endoscopic and Histological Features in Ulcerative Colitis and Crohn's Disease Patients. in Gastroenterology Research & Practice. 2020;2020.
doi:10.1155/2020/2065383 .

Dragašević, Sanja, Sokić-Milutinović, Aleksandra, Stojković-Lalošević, Milica, Milovanović, Tamara, Đuranović, Srđan, Jovanović, Ivan, Rajić, Sanja, Stojković, Mirjana, Miličić, Biljana, Kmezić, Stefan, Oluić, Branislav, Aleksić, Marko, Pavlović-Marković, Aleksandra, Popović, Dragan, "Correlation of Patient-Reported Outcome (PRO-2) with Endoscopic and Histological Features in Ulcerative Colitis and Crohn's Disease Patients" in Gastroenterology Research & Practice, 2020 (2020),
https://doi.org/10.1155/2020/2065383 . .

TY  - JOUR
AU  - Alempijević, Tamara
AU  - Sokić-Milutinović, Aleksandra
AU  - Pavlović-Marković, Aleksandra
AU  - Jesic-Vukicević, Rada
AU  - Miličić, Biljana
AU  - Macut, Đuro
AU  - Popović, Dragan
AU  - Tomić, Dragan
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1740
AB  - Primary biliary cirrhosis (PBC) is a chronic, progressive liver disease with elevated serum lipids. It remains unclear if hyperlipidemia increases the risk for atherosclerosis in PBC patients. Metabolic syndrome (MS) promotes the development of atherosclerotic cardiovascular disease due to abdominal obesity and insulin resistance. The aim of this study was to assess incidence and parameters of MS, as well as subcutaneous and visceral fat using noninvasive ultrasonographic measurement in patients with PBC in our population. We included 55 patients with PBC and 44 age- and sex-matched healthy controls (CG-control group). Anthropometric measurements (weight, height, and waist circumference), age, sex, and body mass index were recorded for patients and controls. Laboratory tests for assessing MS and liver function tests were analyzed. We used ultrasonography to determine subcutaneous and visceral fat diameter and area (SF, VF and SA, VA, respectively), as well as perirenal fat diameter (PF). Patients with PBC had significantly higher levels of cholesterol and liver function tests. There were no statistically significant difference in serum insulin and HOMA levels, as well as incidence of MS was diagnosed in 30.9 % (17/55) PBC patients and 43.2 % (19/44) controls. We registered lower amount of VF (PBC:10.92 +/- 3.63 mm, CG:16.84 +/- 5.51 mm,  lt  0.001), VA (PBC:403.64 +/- 166.97 mm(2), CG:720.57 +/- 272.50 mm(2),  lt  0.001), and PF (PBC:7.03 +/- 1.82 mm, CG 10.49 +/- 2.70 mm,  lt  0.001) in patients with PBC. MS is not more frequent in patients with PBC compared with healthy volunteers in our population. Lower amount of VF could be related to lower risk for cardiovascular events in PBC patients.
PB  - Springer Wien, Wien
T2  - Wiener Klinische Wochenschrift
T1  - Assessment of metabolic syndrome in patients with primary biliary cirrhosis
VL  - 124
IS  - 7-8
SP  - 251
EP  - 255
DO  - 10.1007/s00508-012-0162-9
ER  - 

@article{
author = "Alempijević, Tamara and Sokić-Milutinović, Aleksandra and Pavlović-Marković, Aleksandra and Jesic-Vukicević, Rada and Miličić, Biljana and Macut, Đuro and Popović, Dragan and Tomić, Dragan",
year = "2012",
abstract = "Primary biliary cirrhosis (PBC) is a chronic, progressive liver disease with elevated serum lipids. It remains unclear if hyperlipidemia increases the risk for atherosclerosis in PBC patients. Metabolic syndrome (MS) promotes the development of atherosclerotic cardiovascular disease due to abdominal obesity and insulin resistance. The aim of this study was to assess incidence and parameters of MS, as well as subcutaneous and visceral fat using noninvasive ultrasonographic measurement in patients with PBC in our population. We included 55 patients with PBC and 44 age- and sex-matched healthy controls (CG-control group). Anthropometric measurements (weight, height, and waist circumference), age, sex, and body mass index were recorded for patients and controls. Laboratory tests for assessing MS and liver function tests were analyzed. We used ultrasonography to determine subcutaneous and visceral fat diameter and area (SF, VF and SA, VA, respectively), as well as perirenal fat diameter (PF). Patients with PBC had significantly higher levels of cholesterol and liver function tests. There were no statistically significant difference in serum insulin and HOMA levels, as well as incidence of MS was diagnosed in 30.9 % (17/55) PBC patients and 43.2 % (19/44) controls. We registered lower amount of VF (PBC:10.92 +/- 3.63 mm, CG:16.84 +/- 5.51 mm,  lt  0.001), VA (PBC:403.64 +/- 166.97 mm(2), CG:720.57 +/- 272.50 mm(2),  lt  0.001), and PF (PBC:7.03 +/- 1.82 mm, CG 10.49 +/- 2.70 mm,  lt  0.001) in patients with PBC. MS is not more frequent in patients with PBC compared with healthy volunteers in our population. Lower amount of VF could be related to lower risk for cardiovascular events in PBC patients.",
publisher = "Springer Wien, Wien",
journal = "Wiener Klinische Wochenschrift",
title = "Assessment of metabolic syndrome in patients with primary biliary cirrhosis",
volume = "124",
number = "7-8",
pages = "251-255",
doi = "10.1007/s00508-012-0162-9"
}

Alempijević, T., Sokić-Milutinović, A., Pavlović-Marković, A., Jesic-Vukicević, R., Miličić, B., Macut, Đ., Popović, D.,& Tomić, D.. (2012). Assessment of metabolic syndrome in patients with primary biliary cirrhosis. in Wiener Klinische Wochenschrift
Springer Wien, Wien., 124(7-8), 251-255.
https://doi.org/10.1007/s00508-012-0162-9

Alempijević T, Sokić-Milutinović A, Pavlović-Marković A, Jesic-Vukicević R, Miličić B, Macut Đ, Popović D, Tomić D. Assessment of metabolic syndrome in patients with primary biliary cirrhosis. in Wiener Klinische Wochenschrift. 2012;124(7-8):251-255.
doi:10.1007/s00508-012-0162-9 .

Alempijević, Tamara, Sokić-Milutinović, Aleksandra, Pavlović-Marković, Aleksandra, Jesic-Vukicević, Rada, Miličić, Biljana, Macut, Đuro, Popović, Dragan, Tomić, Dragan, "Assessment of metabolic syndrome in patients with primary biliary cirrhosis" in Wiener Klinische Wochenschrift, 124, no. 7-8 (2012):251-255,
https://doi.org/10.1007/s00508-012-0162-9 . .

TY  - JOUR
AU  - Alempijević, Tamara
AU  - Sokić-Milutinović, Aleksandra
AU  - Miličić, Biljana
AU  - Jesić, Rada
AU  - Balović, Ana
AU  - Popović, Dragan
AU  - Krstić, Miodrag
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1712
AB  - Background/aims: Portal hypertension and development of esophageal varices is one of the major complications of liver cirrhosis. The aim of our study was to evaluate the possibility of the presence of esophageal varices and their size using biochemical and ultrasonography parameters in patients with alcoholic liver cirrhosis. Material and Methods: We included in our study 86 patients (74 males, mean age 55 +/- 7) with alcoholic liver cirrhosis. The control group consisted of 102 patients with cirrhosis of other etiologies. All patients underwent a complete biochemical work up, upper digestive endoscopy and ultrasonography examination. The right liver lobe diameter/albumin and platelet count/spleen diameter ratios were calculated. The correlation of the calculated ratios with the presence and degree of esophageal varices in patients with liver cirrhosis was also determined. Results: The mean value of right liver lobe diameter-albumin ratio was 6.15 +/- 1.77, and statistically significantly differed from values determined in the control group (4.97 +/- 1.68). The mean platelet count-spleen diameter ratio was 972.5 +/- 599.0 in alcoholic liver cirrhosis and 1055.9 +/- 821.3 in controls (p>0.05). In patients with alcoholic liver cirrhosis, none of the analyzed noninvasive markers was shown to be a good predictor of the presence and size of esophageal varices. Conclusions: Despite the important role of noninvasive markers in providing information pertinent to determination of esophageal varices in patients with liver cirrhosis, these markers have limited relevance in patients with alcoholic cirrhosis.
PB  - Turkish Soc Gastroenterology, Abidinpasa
T2  - Turkish Journal of Gastroenterology
T1  - Noninvasive assessment of portal hypertension in patients with alcoholic cirrhosis
VL  - 23
IS  - 3
SP  - 239
EP  - 246
DO  - 10.4318/tjg.2012.0463
ER  - 

@article{
author = "Alempijević, Tamara and Sokić-Milutinović, Aleksandra and Miličić, Biljana and Jesić, Rada and Balović, Ana and Popović, Dragan and Krstić, Miodrag",
year = "2012",
abstract = "Background/aims: Portal hypertension and development of esophageal varices is one of the major complications of liver cirrhosis. The aim of our study was to evaluate the possibility of the presence of esophageal varices and their size using biochemical and ultrasonography parameters in patients with alcoholic liver cirrhosis. Material and Methods: We included in our study 86 patients (74 males, mean age 55 +/- 7) with alcoholic liver cirrhosis. The control group consisted of 102 patients with cirrhosis of other etiologies. All patients underwent a complete biochemical work up, upper digestive endoscopy and ultrasonography examination. The right liver lobe diameter/albumin and platelet count/spleen diameter ratios were calculated. The correlation of the calculated ratios with the presence and degree of esophageal varices in patients with liver cirrhosis was also determined. Results: The mean value of right liver lobe diameter-albumin ratio was 6.15 +/- 1.77, and statistically significantly differed from values determined in the control group (4.97 +/- 1.68). The mean platelet count-spleen diameter ratio was 972.5 +/- 599.0 in alcoholic liver cirrhosis and 1055.9 +/- 821.3 in controls (p>0.05). In patients with alcoholic liver cirrhosis, none of the analyzed noninvasive markers was shown to be a good predictor of the presence and size of esophageal varices. Conclusions: Despite the important role of noninvasive markers in providing information pertinent to determination of esophageal varices in patients with liver cirrhosis, these markers have limited relevance in patients with alcoholic cirrhosis.",
publisher = "Turkish Soc Gastroenterology, Abidinpasa",
journal = "Turkish Journal of Gastroenterology",
title = "Noninvasive assessment of portal hypertension in patients with alcoholic cirrhosis",
volume = "23",
number = "3",
pages = "239-246",
doi = "10.4318/tjg.2012.0463"
}

Alempijević, T., Sokić-Milutinović, A., Miličić, B., Jesić, R., Balović, A., Popović, D.,& Krstić, M.. (2012). Noninvasive assessment of portal hypertension in patients with alcoholic cirrhosis. in Turkish Journal of Gastroenterology
Turkish Soc Gastroenterology, Abidinpasa., 23(3), 239-246.
https://doi.org/10.4318/tjg.2012.0463

Alempijević T, Sokić-Milutinović A, Miličić B, Jesić R, Balović A, Popović D, Krstić M. Noninvasive assessment of portal hypertension in patients with alcoholic cirrhosis. in Turkish Journal of Gastroenterology. 2012;23(3):239-246.
doi:10.4318/tjg.2012.0463 .

Alempijević, Tamara, Sokić-Milutinović, Aleksandra, Miličić, Biljana, Jesić, Rada, Balović, Ana, Popović, Dragan, Krstić, Miodrag, "Noninvasive assessment of portal hypertension in patients with alcoholic cirrhosis" in Turkish Journal of Gastroenterology, 23, no. 3 (2012):239-246,
https://doi.org/10.4318/tjg.2012.0463 . .

TY  - JOUR
AU  - Lukić, Snezana
AU  - Nikolić, Aleksandra
AU  - Alempijević, Tamara
AU  - Popović, Dragan
AU  - Sokić-Milutinović, Aleksandra
AU  - Ugljesić, Milenko
AU  - Knežević, Srbislav
AU  - Miličić, Biljana
AU  - Dinić, Dragica
AU  - Radojković, Dragica
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1613
AB  - The purpose of this study was to determine the frequency of angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and to investigate its role as a potential risk factor in patients with chronic pancreatitis and pancreatic cancer. Deletion polymorphism of the 287-bp fragment of intron 16 of the ACE gene results in higher levels of circulating enzyme and therefore may represent a risk factor for disease development. The study included 55 patients with chronic pancreatitis, 45 patients with pancreatic cancer and 128 healthy subjects. The presence of I and D variants in the ACE gene was analyzed by a polymerase chain reaction (PCR) method. Distribution of ACE ID genotypes was analyzed by means of logistic regression. When chronic pancreatitis and pancreatic cancer groups were compared in the univariate analysis, the following factors were identified as statistically significant predictors of pancreatic disease: age, gender, smoking, fat intake, ACE II genotype and ACE DD genotype. However, in the multivariate analysis, only age, gender and smoking were singled out as predictors for the occurrence of pancreatic disease. Our findings indicate that the ACE I/D polymorphism could play a role in the development of chronic pancreatitis and pancreatic cancer through interaction with other genetic and environmental factors.
PB  - Karger, Basel
T2  - Digestive Surgery
T1  - Angiotensin-Converting Enzyme Gene Insertion/Deletion Polymorphism in Patients with Chronic Pancreatitis and Pancreatic Cancer
VL  - 28
IS  - 4
SP  - 258
EP  - 262
DO  - 10.1159/000328666
ER  - 

@article{
author = "Lukić, Snezana and Nikolić, Aleksandra and Alempijević, Tamara and Popović, Dragan and Sokić-Milutinović, Aleksandra and Ugljesić, Milenko and Knežević, Srbislav and Miličić, Biljana and Dinić, Dragica and Radojković, Dragica",
year = "2011",
abstract = "The purpose of this study was to determine the frequency of angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and to investigate its role as a potential risk factor in patients with chronic pancreatitis and pancreatic cancer. Deletion polymorphism of the 287-bp fragment of intron 16 of the ACE gene results in higher levels of circulating enzyme and therefore may represent a risk factor for disease development. The study included 55 patients with chronic pancreatitis, 45 patients with pancreatic cancer and 128 healthy subjects. The presence of I and D variants in the ACE gene was analyzed by a polymerase chain reaction (PCR) method. Distribution of ACE ID genotypes was analyzed by means of logistic regression. When chronic pancreatitis and pancreatic cancer groups were compared in the univariate analysis, the following factors were identified as statistically significant predictors of pancreatic disease: age, gender, smoking, fat intake, ACE II genotype and ACE DD genotype. However, in the multivariate analysis, only age, gender and smoking were singled out as predictors for the occurrence of pancreatic disease. Our findings indicate that the ACE I/D polymorphism could play a role in the development of chronic pancreatitis and pancreatic cancer through interaction with other genetic and environmental factors.",
publisher = "Karger, Basel",
journal = "Digestive Surgery",
title = "Angiotensin-Converting Enzyme Gene Insertion/Deletion Polymorphism in Patients with Chronic Pancreatitis and Pancreatic Cancer",
volume = "28",
number = "4",
pages = "258-262",
doi = "10.1159/000328666"
}

Lukić, S., Nikolić, A., Alempijević, T., Popović, D., Sokić-Milutinović, A., Ugljesić, M., Knežević, S., Miličić, B., Dinić, D.,& Radojković, D.. (2011). Angiotensin-Converting Enzyme Gene Insertion/Deletion Polymorphism in Patients with Chronic Pancreatitis and Pancreatic Cancer. in Digestive Surgery
Karger, Basel., 28(4), 258-262.
https://doi.org/10.1159/000328666

Lukić S, Nikolić A, Alempijević T, Popović D, Sokić-Milutinović A, Ugljesić M, Knežević S, Miličić B, Dinić D, Radojković D. Angiotensin-Converting Enzyme Gene Insertion/Deletion Polymorphism in Patients with Chronic Pancreatitis and Pancreatic Cancer. in Digestive Surgery. 2011;28(4):258-262.
doi:10.1159/000328666 .

Lukić, Snezana, Nikolić, Aleksandra, Alempijević, Tamara, Popović, Dragan, Sokić-Milutinović, Aleksandra, Ugljesić, Milenko, Knežević, Srbislav, Miličić, Biljana, Dinić, Dragica, Radojković, Dragica, "Angiotensin-Converting Enzyme Gene Insertion/Deletion Polymorphism in Patients with Chronic Pancreatitis and Pancreatic Cancer" in Digestive Surgery, 28, no. 4 (2011):258-262,
https://doi.org/10.1159/000328666 . .