TY  - JOUR
AU  - Miletić, Vesna
AU  - Marjanović, Jovana
AU  - Veljović, Đorđe
AU  - Stasić, Jovana
AU  - Petrović, Violeta
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2378
AB  - Objective To determine color changes in bulk-fill composite and universal composite restorations with dissimilar dentin replacement materials in extracted teeth after staining in red wine. Materials and Methods Cylindrical, 4 mm deep, class I cavities were prepared in 140 human molars. Bottom 2 mm was restored with Biodentine (Septodont), everX posterior (GC) or experimental HAP inserts. Each dentin replacement material was covered with a 2-mm layer of a universal composite Filtek Z250 or Z550 (3M ESPE) or Gradia Posterior (GC). Groups combining top composite layer and the underlying dentin replacement were designated as "composite_dentin replacement." Filtek Bulk Fill (3M ESPE) and Tetric EvoCeram Bulk Fill (Ivoclar Vivadent) were placed as a single 4-mm layer. Color measurements were performed using Vita Easyshade 4.0 (Vita Zahnfabrik) initially and after 48-hours storage in red wine at 37 degrees C. Results Color differences (Delta E-oo) ranged between 2.1 +/- 0.7 (Z250_HAP) and 7.8 +/- 1.1 (Z550_everX). EverX resulted in higher Delta E-oo of the overlying composite than HAP (P  lt  .001) and Biodentine (P = .006). Generally, Delta E-oo was affected more by decreasing lightness (Delta L ') than changes in chroma (Delta C '). Conclusions EverX resulted in higher Delta E-oo of the restoration than Biodentine and experimental HAP after staining in red wine. No significant differences in Delta E-oo may be expected in different composites with the same underlying dentin replacement material. The same was generally true for bulk-fill and universal composites. Clinical Significance Similar extent of color changes may be expected in bulk-fill and universal composites. Highly translucent everX might exhibit greater color differences irrespective of the capping composite than non-translucent materials. Clinicians have a wider choice of composite materials to cover a particular dentin replacement material, for example, everX or Biodentine, as similar color differences may be expected in various overlying composite brands.
PB  - Wiley, Hoboken
T2  - Journal of Esthetic & Restorative Dentistry
T1  - Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials
VL  - 31
IS  - 5
SP  - 520
EP  - 528
DO  - 10.1111/jerd.12529
ER  - 

@article{
author = "Miletić, Vesna and Marjanović, Jovana and Veljović, Đorđe and Stasić, Jovana and Petrović, Violeta",
year = "2019",
abstract = "Objective To determine color changes in bulk-fill composite and universal composite restorations with dissimilar dentin replacement materials in extracted teeth after staining in red wine. Materials and Methods Cylindrical, 4 mm deep, class I cavities were prepared in 140 human molars. Bottom 2 mm was restored with Biodentine (Septodont), everX posterior (GC) or experimental HAP inserts. Each dentin replacement material was covered with a 2-mm layer of a universal composite Filtek Z250 or Z550 (3M ESPE) or Gradia Posterior (GC). Groups combining top composite layer and the underlying dentin replacement were designated as "composite_dentin replacement." Filtek Bulk Fill (3M ESPE) and Tetric EvoCeram Bulk Fill (Ivoclar Vivadent) were placed as a single 4-mm layer. Color measurements were performed using Vita Easyshade 4.0 (Vita Zahnfabrik) initially and after 48-hours storage in red wine at 37 degrees C. Results Color differences (Delta E-oo) ranged between 2.1 +/- 0.7 (Z250_HAP) and 7.8 +/- 1.1 (Z550_everX). EverX resulted in higher Delta E-oo of the overlying composite than HAP (P  lt  .001) and Biodentine (P = .006). Generally, Delta E-oo was affected more by decreasing lightness (Delta L ') than changes in chroma (Delta C '). Conclusions EverX resulted in higher Delta E-oo of the restoration than Biodentine and experimental HAP after staining in red wine. No significant differences in Delta E-oo may be expected in different composites with the same underlying dentin replacement material. The same was generally true for bulk-fill and universal composites. Clinical Significance Similar extent of color changes may be expected in bulk-fill and universal composites. Highly translucent everX might exhibit greater color differences irrespective of the capping composite than non-translucent materials. Clinicians have a wider choice of composite materials to cover a particular dentin replacement material, for example, everX or Biodentine, as similar color differences may be expected in various overlying composite brands.",
publisher = "Wiley, Hoboken",
journal = "Journal of Esthetic & Restorative Dentistry",
title = "Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials",
volume = "31",
number = "5",
pages = "520-528",
doi = "10.1111/jerd.12529"
}

Miletić, V., Marjanović, J., Veljović, Đ., Stasić, J.,& Petrović, V.. (2019). Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials. in Journal of Esthetic & Restorative Dentistry
Wiley, Hoboken., 31(5), 520-528.
https://doi.org/10.1111/jerd.12529

Miletić V, Marjanović J, Veljović Đ, Stasić J, Petrović V. Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials. in Journal of Esthetic & Restorative Dentistry. 2019;31(5):520-528.
doi:10.1111/jerd.12529 .

Miletić, Vesna, Marjanović, Jovana, Veljović, Đorđe, Stasić, Jovana, Petrović, Violeta, "Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials" in Journal of Esthetic & Restorative Dentistry, 31, no. 5 (2019):520-528,
https://doi.org/10.1111/jerd.12529 . .

TY  - JOUR
AU  - Petrović, Violeta
AU  - Stasić, Jovana
AU  - Komlenić, Vojislav
AU  - Savić-Stanković, Tatjana
AU  - Latković, Marina
AU  - Miletić, Vesna
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2377
AB  - The objective of this study was to measure temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following a simulated procedure of direct pulp capping. Class I cavities with a microperforation at the pulp horn were prepared in extracted human molar teeth. The complete procedure of direct pulp capping and cavity restoration was performed with the root part of extracted teeth fixed in a water bath at 37 degrees C. Mineral trioxide aggregate, bioactive dentin substitute or calcium-hydroxide paste were used as pulp capping materials. Cavities were restored with a light-cured or chemically-cured resin-modified glass ionomer, universal adhesive and a bulk-fill composite, cured with a high-intensity LED unit. Pulp capping materials caused a slight temperature decrease. Lower temperature increase was recorded during light-curing of the glass ionomer liner after direct capping with mineral trioxide aggregate and calcium-hydroxide than that recorded for the bioactive dentin substitute. Adhesive light-curing increased temperature in all groups with higher mean temperatures in groups with chemically-cured as compared to those for the light-cured glass ionomer liner. Direct pulp capping with mineral trioxide aggregate or calcium-hydroxide followed by the light-cured resin-modified glass ionomer liner and a bonded bulk-fill composite restoration induced temperature changes below the potentially adverse threshold of 42.5 degrees C.
PB  - Savez hemijskih inženjera, Beograd
T2  - Hemijska Industrija
T1  - Temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following simulated direct pulp capping
VL  - 73
IS  - 4
SP  - 239
EP  - 248
DO  - 10.2298/HEMIND190504020P
ER  - 

@article{
author = "Petrović, Violeta and Stasić, Jovana and Komlenić, Vojislav and Savić-Stanković, Tatjana and Latković, Marina and Miletić, Vesna",
year = "2019",
abstract = "The objective of this study was to measure temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following a simulated procedure of direct pulp capping. Class I cavities with a microperforation at the pulp horn were prepared in extracted human molar teeth. The complete procedure of direct pulp capping and cavity restoration was performed with the root part of extracted teeth fixed in a water bath at 37 degrees C. Mineral trioxide aggregate, bioactive dentin substitute or calcium-hydroxide paste were used as pulp capping materials. Cavities were restored with a light-cured or chemically-cured resin-modified glass ionomer, universal adhesive and a bulk-fill composite, cured with a high-intensity LED unit. Pulp capping materials caused a slight temperature decrease. Lower temperature increase was recorded during light-curing of the glass ionomer liner after direct capping with mineral trioxide aggregate and calcium-hydroxide than that recorded for the bioactive dentin substitute. Adhesive light-curing increased temperature in all groups with higher mean temperatures in groups with chemically-cured as compared to those for the light-cured glass ionomer liner. Direct pulp capping with mineral trioxide aggregate or calcium-hydroxide followed by the light-cured resin-modified glass ionomer liner and a bonded bulk-fill composite restoration induced temperature changes below the potentially adverse threshold of 42.5 degrees C.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Hemijska Industrija",
title = "Temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following simulated direct pulp capping",
volume = "73",
number = "4",
pages = "239-248",
doi = "10.2298/HEMIND190504020P"
}

Petrović, V., Stasić, J., Komlenić, V., Savić-Stanković, T., Latković, M.,& Miletić, V.. (2019). Temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following simulated direct pulp capping. in Hemijska Industrija
Savez hemijskih inženjera, Beograd., 73(4), 239-248.
https://doi.org/10.2298/HEMIND190504020P

Petrović V, Stasić J, Komlenić V, Savić-Stanković T, Latković M, Miletić V. Temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following simulated direct pulp capping. in Hemijska Industrija. 2019;73(4):239-248.
doi:10.2298/HEMIND190504020P .

Petrović, Violeta, Stasić, Jovana, Komlenić, Vojislav, Savić-Stanković, Tatjana, Latković, Marina, Miletić, Vesna, "Temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following simulated direct pulp capping" in Hemijska Industrija, 73, no. 4 (2019):239-248,
https://doi.org/10.2298/HEMIND190504020P . .

TY  - THES
AU  - Petrović, Violeta
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2723
AB  - Pljuvačka je sekret koji je u neprekidnom i neposrednom kontaktu sa svim oralnim strukturama. Značaj pljuvačke je održavanje oralne homeostaze, odnosno, očuvanje stalnog biohemijskog sastava oralnih tkiva, što ovaj sekret realizuje svojim brojnim organskim i neorganskim sastojcima. Najznačajnije uloge pljuvačke u pomenutom kontekstu jesu: samočišćenje usta od zaostalih čestica hrane, održavanje fizioloških vrednosti pH, održavanje integriteta čvrstih i mekih tkiva, specifična i nespecifična antimikrobna zaštita, antioksidativna zaštita. U zaštiti oralnih tkiva od štetnog delovanja slobodnih radikala značajnu ulogu imaju antioksidansi. U pljuvački su prisutni neenzimski i enzimski antioksidansi. Enzimi pljuvačke koji ispoljavaju antioksidativnu sposobnost su: superoksid dizmutaza, oralna peroksidaza, katalaza i glutation peroksidaza. U neenzimske antioksidanse pljuvačke ubrajaju se: mokraćna kiselina, albumin, vitamin C i glutation. Superoksid dizmutaza (SOD) katalizuje reakciju dizmutacije superoksid anjon radikala (O2) u vodonik peroksid (H2O2) i kiseonik (O2). U toku ove reakcije jedan O2 se oksiduje u O2, a drugi O2 se redukuje u H2O2 ; 2O2 . + 2H+ ⇒ H2O2 + O2. Oralna peroksidaza (OP) je enzim pljuvačke koji se sastoji iz dva peroksidazna enzima: salivarne peroksidaze (80%) i mijeloperoksidaze (20%). Ona je naznačajniji enzimski antioksidans pljuvačke.
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Antioksidansi pljuvačke
UR  - https://hdl.handle.net/21.15107/rcub_smile_2723
ER  - 

@misc{
author = "Petrović, Violeta",
year = "2019",
abstract = "Pljuvačka je sekret koji je u neprekidnom i neposrednom kontaktu sa svim oralnim strukturama. Značaj pljuvačke je održavanje oralne homeostaze, odnosno, očuvanje stalnog biohemijskog sastava oralnih tkiva, što ovaj sekret realizuje svojim brojnim organskim i neorganskim sastojcima. Najznačajnije uloge pljuvačke u pomenutom kontekstu jesu: samočišćenje usta od zaostalih čestica hrane, održavanje fizioloških vrednosti pH, održavanje integriteta čvrstih i mekih tkiva, specifična i nespecifična antimikrobna zaštita, antioksidativna zaštita. U zaštiti oralnih tkiva od štetnog delovanja slobodnih radikala značajnu ulogu imaju antioksidansi. U pljuvački su prisutni neenzimski i enzimski antioksidansi. Enzimi pljuvačke koji ispoljavaju antioksidativnu sposobnost su: superoksid dizmutaza, oralna peroksidaza, katalaza i glutation peroksidaza. U neenzimske antioksidanse pljuvačke ubrajaju se: mokraćna kiselina, albumin, vitamin C i glutation. Superoksid dizmutaza (SOD) katalizuje reakciju dizmutacije superoksid anjon radikala (O2) u vodonik peroksid (H2O2) i kiseonik (O2). U toku ove reakcije jedan O2 se oksiduje u O2, a drugi O2 se redukuje u H2O2 ; 2O2 . + 2H+ ⇒ H2O2 + O2. Oralna peroksidaza (OP) je enzim pljuvačke koji se sastoji iz dva peroksidazna enzima: salivarne peroksidaze (80%) i mijeloperoksidaze (20%). Ona je naznačajniji enzimski antioksidans pljuvačke.",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Antioksidansi pljuvačke",
url = "https://hdl.handle.net/21.15107/rcub_smile_2723"
}

Petrović, V.. (2019). Antioksidansi pljuvačke. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_2723

Petrović V. Antioksidansi pljuvačke. 2019;.
https://hdl.handle.net/21.15107/rcub_smile_2723 .

Petrović, Violeta, "Antioksidansi pljuvačke" (2019),
https://hdl.handle.net/21.15107/rcub_smile_2723 .

TY  - CHAP
AU  - Opačić-Galić, Vanja
AU  - Petrović, Violeta
AU  - Popović-Bajić, Marijana
AU  - Jokanović, Vukoman
AU  - Živković, Slavoljub
AU  - Nikolić, Biljana
AU  - Mitić-Ćulafić, Dragana
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2371
PB  - Springer International Publishing
T2  - Dental Applications of Nanotechnology
T1  - Physical properties and biocompatibility of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite
SP  - 247
EP  - 271
DO  - 10.1007/978-3-319-97634-1_13
ER  - 

@inbook{
author = "Opačić-Galić, Vanja and Petrović, Violeta and Popović-Bajić, Marijana and Jokanović, Vukoman and Živković, Slavoljub and Nikolić, Biljana and Mitić-Ćulafić, Dragana",
year = "2018",
publisher = "Springer International Publishing",
journal = "Dental Applications of Nanotechnology",
booktitle = "Physical properties and biocompatibility of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite",
pages = "247-271",
doi = "10.1007/978-3-319-97634-1_13"
}

Opačić-Galić, V., Petrović, V., Popović-Bajić, M., Jokanović, V., Živković, S., Nikolić, B.,& Mitić-Ćulafić, D.. (2018). Physical properties and biocompatibility of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite. in Dental Applications of Nanotechnology
Springer International Publishing., 247-271.
https://doi.org/10.1007/978-3-319-97634-1_13

Opačić-Galić V, Petrović V, Popović-Bajić M, Jokanović V, Živković S, Nikolić B, Mitić-Ćulafić D. Physical properties and biocompatibility of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite. in Dental Applications of Nanotechnology. 2018;:247-271.
doi:10.1007/978-3-319-97634-1_13 .

Opačić-Galić, Vanja, Petrović, Violeta, Popović-Bajić, Marijana, Jokanović, Vukoman, Živković, Slavoljub, Nikolić, Biljana, Mitić-Ćulafić, Dragana, "Physical properties and biocompatibility of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite" in Dental Applications of Nanotechnology (2018):247-271,
https://doi.org/10.1007/978-3-319-97634-1_13 . .

TY  - JOUR
AU  - Opačić-Galić, Vanja
AU  - Stamenić, Zoran
AU  - Petrović, Violeta
AU  - Jokanović, Vukoman
AU  - Živković, Slavoljub
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2358
AB  - Introduction The aim of this study was to compare compressive strength (Cs) of new nanostructural calcium silicate based cement (nCS) with commercial calcium silicate cement and conventional GIC. Methods Four nanostructural materials were tested: nanostructural calcium silicate based cement (nCS) (Jokanović et al.), MTA Plus (Cerkamed, Poland), Fuji IX (GC Corporation, Japan) and Ketac Universal Aplicap (3M ESPE, USA). Five samples of each material were mixed in accordance with manifecturer's guidelines and positioned in metal moulds (ϕ4mm and 6mm). Compressive strength (Cs) expressed in MPa was determined after 24 hours, 7 days and 28 days respectively. Measurements were performed on universal testing equipment (Tinius Olsen, USA) at a crosshead speed of 1mm/min. For processing the results one-way ANOVA and post-hoc test were used. Results The highest values of compressive strength after 24h was found in conventional GIC Fuji IX (mean 38.56±13.31) and Ketac Universal (mean 40.77±7.96). Calcium silicate cements after 24h showed low values of compressive strength (MTA Plus 5.91±0.28 MPa, nCS 1.35±0.36 MPa). After 7 days, FUJI IX 47.42±9.33 MPa and Ketac Universal 35.25±10.60 MPa showed higher value of compressive strength than MTA Plus (15.09±2.77 MPa) and nCS (11.06±0.88 MPa). After 28 days the Cs value for conventional GIC Fuji IX was 48.03±7.82 MPa and Ketac Universal 36.65±11.13 MPa while for calcium silicate cements it was 16.47±1.89 MPa and nCS 14.39±1.63 MPa. There was statistically significant difference (p lt 0.05) in Cs between conventional GIC and CS cements after 24h, 7 and 28 days. Conclusions Calcium silicate cements initially showed lower values of compressive strength than conventional GIC that increased over time.
AB  - Uvod Cilj ovog rada je bio da se proveri kompresivna čvrstoća (KČ) novog nanostrukturnog kalcijum-silikatnog cementa (nCS) i uporedi sa komercijalnim kalcijum-silikatnim cementom i konvencionalnim GJC u funkciji vremena. Materijal i metod Testirana su četiri materijala - nanostrukturni CS (Jokanović i sar.), MTA Plus (Cerkamed, Poland), Fuji IX (GC Corporation, Japan) and Ketac Universal Aplicap (3M ESPE, USA). Po pet uzoraka za svaki materijal je zamešano po proizvođačkom uputstvu i postavljano u metalne kalupe (ϕ 4 mm i 6 mm visoke). KČ, izražena u megapaskalima, merena je posle 24 sata i posle 7 i 28 dana na univerzalnoj test mašini (Tinius Olsen, USA) sa brzinom utiskivača od 1 mm/min. Dobijeni rezultati su statistički obrađeni one-way ANOVA i post hoc Tukey, s testovima. Resultati Posle 24 sata najveću KČ imao je FUJI IX (38,56 ± 13,31 MPa), zatim Ketac Univerzal (40,77 ± 7,96 MPa). Kalcijum-silikatni cementi su pokazali niže vrednosti KČ 24 sata posle mešanja i to MTA 5,91 ± 0,28, a nCS 1,35 ± 0,36 MPa. Posle sedam dana KČ za FUJI IX je bila 47,72 ± 9,33 MPa, a za Ketac Universal 35,25 ± 10,60 MPa, dok je vrednost za MTA bila 15,09 ± 2,77 MPa, a nCS 11,06 ± 0,88. Posle 28 dana KČ za FUJI IX je bila 48,03 ± 7,82 MPa, a za Ketac 36,65 ± 11,13 MPa. KČ kalcijum-silikatnih cemenata posle 28 dana je bila 16,47 ± 1,89 za MTA, a za nCS 14,39 ± 1,63 MPa, bez statističi značajne razlike između njih. Između konvencionalnih GJC i CS cemenata postoji statistički značajna razlika (p  lt  0,05) posle 24 h, kao i posle 7 i 28 dana. Zaključak Kalcijum-silikatni cementi su inicijalno pokazali niže vrednosti KČ u odnosu na konvencionalne GJC, ali su se one povećavale u funkciji vremena.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Compressive strength of calcium silicate-based cement
T1  - Ispitivanje kompresivne čvrstoće kalcijum-silikatnih cemenata
VL  - 65
IS  - 1
SP  - 7
EP  - 13
DO  - 10.2478/sdj-2018-0001
ER  - 

@article{
author = "Opačić-Galić, Vanja and Stamenić, Zoran and Petrović, Violeta and Jokanović, Vukoman and Živković, Slavoljub",
year = "2018",
abstract = "Introduction The aim of this study was to compare compressive strength (Cs) of new nanostructural calcium silicate based cement (nCS) with commercial calcium silicate cement and conventional GIC. Methods Four nanostructural materials were tested: nanostructural calcium silicate based cement (nCS) (Jokanović et al.), MTA Plus (Cerkamed, Poland), Fuji IX (GC Corporation, Japan) and Ketac Universal Aplicap (3M ESPE, USA). Five samples of each material were mixed in accordance with manifecturer's guidelines and positioned in metal moulds (ϕ4mm and 6mm). Compressive strength (Cs) expressed in MPa was determined after 24 hours, 7 days and 28 days respectively. Measurements were performed on universal testing equipment (Tinius Olsen, USA) at a crosshead speed of 1mm/min. For processing the results one-way ANOVA and post-hoc test were used. Results The highest values of compressive strength after 24h was found in conventional GIC Fuji IX (mean 38.56±13.31) and Ketac Universal (mean 40.77±7.96). Calcium silicate cements after 24h showed low values of compressive strength (MTA Plus 5.91±0.28 MPa, nCS 1.35±0.36 MPa). After 7 days, FUJI IX 47.42±9.33 MPa and Ketac Universal 35.25±10.60 MPa showed higher value of compressive strength than MTA Plus (15.09±2.77 MPa) and nCS (11.06±0.88 MPa). After 28 days the Cs value for conventional GIC Fuji IX was 48.03±7.82 MPa and Ketac Universal 36.65±11.13 MPa while for calcium silicate cements it was 16.47±1.89 MPa and nCS 14.39±1.63 MPa. There was statistically significant difference (p lt 0.05) in Cs between conventional GIC and CS cements after 24h, 7 and 28 days. Conclusions Calcium silicate cements initially showed lower values of compressive strength than conventional GIC that increased over time., Uvod Cilj ovog rada je bio da se proveri kompresivna čvrstoća (KČ) novog nanostrukturnog kalcijum-silikatnog cementa (nCS) i uporedi sa komercijalnim kalcijum-silikatnim cementom i konvencionalnim GJC u funkciji vremena. Materijal i metod Testirana su četiri materijala - nanostrukturni CS (Jokanović i sar.), MTA Plus (Cerkamed, Poland), Fuji IX (GC Corporation, Japan) and Ketac Universal Aplicap (3M ESPE, USA). Po pet uzoraka za svaki materijal je zamešano po proizvođačkom uputstvu i postavljano u metalne kalupe (ϕ 4 mm i 6 mm visoke). KČ, izražena u megapaskalima, merena je posle 24 sata i posle 7 i 28 dana na univerzalnoj test mašini (Tinius Olsen, USA) sa brzinom utiskivača od 1 mm/min. Dobijeni rezultati su statistički obrađeni one-way ANOVA i post hoc Tukey, s testovima. Resultati Posle 24 sata najveću KČ imao je FUJI IX (38,56 ± 13,31 MPa), zatim Ketac Univerzal (40,77 ± 7,96 MPa). Kalcijum-silikatni cementi su pokazali niže vrednosti KČ 24 sata posle mešanja i to MTA 5,91 ± 0,28, a nCS 1,35 ± 0,36 MPa. Posle sedam dana KČ za FUJI IX je bila 47,72 ± 9,33 MPa, a za Ketac Universal 35,25 ± 10,60 MPa, dok je vrednost za MTA bila 15,09 ± 2,77 MPa, a nCS 11,06 ± 0,88. Posle 28 dana KČ za FUJI IX je bila 48,03 ± 7,82 MPa, a za Ketac 36,65 ± 11,13 MPa. KČ kalcijum-silikatnih cemenata posle 28 dana je bila 16,47 ± 1,89 za MTA, a za nCS 14,39 ± 1,63 MPa, bez statističi značajne razlike između njih. Između konvencionalnih GJC i CS cemenata postoji statistički značajna razlika (p  lt  0,05) posle 24 h, kao i posle 7 i 28 dana. Zaključak Kalcijum-silikatni cementi su inicijalno pokazali niže vrednosti KČ u odnosu na konvencionalne GJC, ali su se one povećavale u funkciji vremena.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Compressive strength of calcium silicate-based cement, Ispitivanje kompresivne čvrstoće kalcijum-silikatnih cemenata",
volume = "65",
number = "1",
pages = "7-13",
doi = "10.2478/sdj-2018-0001"
}

Opačić-Galić, V., Stamenić, Z., Petrović, V., Jokanović, V.,& Živković, S.. (2018). Compressive strength of calcium silicate-based cement. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 65(1), 7-13.
https://doi.org/10.2478/sdj-2018-0001

Opačić-Galić V, Stamenić Z, Petrović V, Jokanović V, Živković S. Compressive strength of calcium silicate-based cement. in Stomatološki glasnik Srbije. 2018;65(1):7-13.
doi:10.2478/sdj-2018-0001 .

Opačić-Galić, Vanja, Stamenić, Zoran, Petrović, Violeta, Jokanović, Vukoman, Živković, Slavoljub, "Compressive strength of calcium silicate-based cement" in Stomatološki glasnik Srbije, 65, no. 1 (2018):7-13,
https://doi.org/10.2478/sdj-2018-0001 . .

TY  - JOUR
AU  - Opačić-Galić, Vanja
AU  - Petrović, Violeta
AU  - Jokanović, Vukoman
AU  - Živković, Slavoljub
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2261
AB  - Introduction/Objective: Development of materials which could be used as biological bone substitutes is one of the most valuable and active fields of biomaterial research. The goal of the study was to research the reaction of tissue on calcium silicate- (CS) and hydroxyapatite-based (CS-HA) newly synthesized nanomaterials, after being implanted into the subcutaneous tissue of a rats and direct pulp capping of rabbit teeth. Methods: The tested materials were implanted in 40 Wistar male rats, sacrificed after seven, 15, 30, and 60 days. The direct pulp capping was performed on the teeth of rabbits. Cavities were prepared on the vestibular surface of the incisors. The animals were sacrificed after 10 and 15 days. The control material was mineral trioxide aggregate (MTA). Histological analysis covered the tracking of inflammatory reaction cellular components, presence of gigantic cells, and necrosis of the tissue. Results: Seven days after the implantation, the strongest inflammatory response was given by the MTA (3.3 ± 0.48), while CS and CS-HA scored 3 ± 0.71. After 60 days, the rate of inflammatory reactions dropped, which was the least visible with CS-HA (0.2 ± 0.45). The least visible inflammatory reaction of the rabbits’ pulp tissue was spotted with the CS (1.83 ± 0.75), than with the MTA and CS-HA (2.67 ± 1.53, 3 ± 0.63). Conclusion: The newly synthesized materials caused a slight reaction of the subcutaneous tissue. CS-HA showed the best tissue tolerance. Nanostructural biomaterials caused a slight to moderate inflammatory reaction of the rabbits’ pulp tissue only in the immediate vicinity of the implanted material.
AB  - Uvod/Cilj: Usavršavanje materijala koji bi mogli da se koriste kao biološke zamene kosti jedna je od najznačajnijih i najaktivnijih oblasti istraživanja biomaterijala. Cilj ovog rada je bio da se ispita odgovor tkiva na novosintetisane nanomaterijale na bazi kalcijum-silikatnih sistema (KS) i hidroksiapatita (KS-HA) posle implantacije u potkožno tkivo pacova i direktnog prekrivanja pulpe zuba kunića. Metode: U potkožno tkivo 40 vistar pacova su implantirani testirani materijali, a posle 7, 15, 30 i 60 dana životinje su žrtvovane. Direktno prekrivanje pulpe je realizovano na zubima kunića. Na vestibularnim površinama sekutića preparisani su kaviteti, a eksponirana pulpa je prekrivana testiranim materijalima. Životinje su žrtvovane posle 10 i 15 dana. Kontrolni materijal u oba eksperimenta je bio mineralni trioksidni agregat (MTA). Histološka analiza je obuhvatila praćenje ćelijske komponente zapaljenja, prisustva gigantskih ćelija i nekroze tkiva. Rezultati: Sedam dana posle supkutane implantacije najjači zapaljenski odgovor dao je MTA (3,30 ± 0,48), dok je za KS i KS-HA on ocenjen sa 3,00 ± 0,71. Posle 60 dana došlo je do opadanja znakova zapaljenja, koje je bilo najmanje izraženo oko KS-HA (0,20 ± 0,45). Najmanje izražena zapaljenska reakcija pulpnog tkiva kunića uočena je kod materijala KS (1,83 ± 0,75), zatim kod MTA i KS-HA (2,67 ± 1,53, 3,00 ± 0,63). Zaključak: Novosintetisani materijali su izazvali blagu zapaljensku reakciju potkožnog tkiva pacova, a KS-HA je pokazao najbolju tkivnu toleranciju. Nanostrukturni biomaterijali KS i KS-HA su uzrokovali blagu do umerenu zapaljensku reakciju pupnog tkiva kunića samo u neposrednoj blizini implantiranog materijala.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Histological evaluation of tissue reactions to newly synthetized calcium silicate-and hydroxyapatite-based bioactive materials: In vivo study
T1  - Histološke reakcije tkiva na novosintetisane bioaktivne materijale na bazi kalcijum-silikatnih sistema i hidroksiapatita – In vivo studija
VL  - 145
IS  - 7-8
SP  - 370
EP  - 377
DO  - 10.2298/SARH160719063O
ER  - 

@article{
author = "Opačić-Galić, Vanja and Petrović, Violeta and Jokanović, Vukoman and Živković, Slavoljub",
year = "2017",
abstract = "Introduction/Objective: Development of materials which could be used as biological bone substitutes is one of the most valuable and active fields of biomaterial research. The goal of the study was to research the reaction of tissue on calcium silicate- (CS) and hydroxyapatite-based (CS-HA) newly synthesized nanomaterials, after being implanted into the subcutaneous tissue of a rats and direct pulp capping of rabbit teeth. Methods: The tested materials were implanted in 40 Wistar male rats, sacrificed after seven, 15, 30, and 60 days. The direct pulp capping was performed on the teeth of rabbits. Cavities were prepared on the vestibular surface of the incisors. The animals were sacrificed after 10 and 15 days. The control material was mineral trioxide aggregate (MTA). Histological analysis covered the tracking of inflammatory reaction cellular components, presence of gigantic cells, and necrosis of the tissue. Results: Seven days after the implantation, the strongest inflammatory response was given by the MTA (3.3 ± 0.48), while CS and CS-HA scored 3 ± 0.71. After 60 days, the rate of inflammatory reactions dropped, which was the least visible with CS-HA (0.2 ± 0.45). The least visible inflammatory reaction of the rabbits’ pulp tissue was spotted with the CS (1.83 ± 0.75), than with the MTA and CS-HA (2.67 ± 1.53, 3 ± 0.63). Conclusion: The newly synthesized materials caused a slight reaction of the subcutaneous tissue. CS-HA showed the best tissue tolerance. Nanostructural biomaterials caused a slight to moderate inflammatory reaction of the rabbits’ pulp tissue only in the immediate vicinity of the implanted material., Uvod/Cilj: Usavršavanje materijala koji bi mogli da se koriste kao biološke zamene kosti jedna je od najznačajnijih i najaktivnijih oblasti istraživanja biomaterijala. Cilj ovog rada je bio da se ispita odgovor tkiva na novosintetisane nanomaterijale na bazi kalcijum-silikatnih sistema (KS) i hidroksiapatita (KS-HA) posle implantacije u potkožno tkivo pacova i direktnog prekrivanja pulpe zuba kunića. Metode: U potkožno tkivo 40 vistar pacova su implantirani testirani materijali, a posle 7, 15, 30 i 60 dana životinje su žrtvovane. Direktno prekrivanje pulpe je realizovano na zubima kunića. Na vestibularnim površinama sekutića preparisani su kaviteti, a eksponirana pulpa je prekrivana testiranim materijalima. Životinje su žrtvovane posle 10 i 15 dana. Kontrolni materijal u oba eksperimenta je bio mineralni trioksidni agregat (MTA). Histološka analiza je obuhvatila praćenje ćelijske komponente zapaljenja, prisustva gigantskih ćelija i nekroze tkiva. Rezultati: Sedam dana posle supkutane implantacije najjači zapaljenski odgovor dao je MTA (3,30 ± 0,48), dok je za KS i KS-HA on ocenjen sa 3,00 ± 0,71. Posle 60 dana došlo je do opadanja znakova zapaljenja, koje je bilo najmanje izraženo oko KS-HA (0,20 ± 0,45). Najmanje izražena zapaljenska reakcija pulpnog tkiva kunića uočena je kod materijala KS (1,83 ± 0,75), zatim kod MTA i KS-HA (2,67 ± 1,53, 3,00 ± 0,63). Zaključak: Novosintetisani materijali su izazvali blagu zapaljensku reakciju potkožnog tkiva pacova, a KS-HA je pokazao najbolju tkivnu toleranciju. Nanostrukturni biomaterijali KS i KS-HA su uzrokovali blagu do umerenu zapaljensku reakciju pupnog tkiva kunića samo u neposrednoj blizini implantiranog materijala.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Histological evaluation of tissue reactions to newly synthetized calcium silicate-and hydroxyapatite-based bioactive materials: In vivo study, Histološke reakcije tkiva na novosintetisane bioaktivne materijale na bazi kalcijum-silikatnih sistema i hidroksiapatita – In vivo studija",
volume = "145",
number = "7-8",
pages = "370-377",
doi = "10.2298/SARH160719063O"
}

Opačić-Galić, V., Petrović, V., Jokanović, V.,& Živković, S.. (2017). Histological evaluation of tissue reactions to newly synthetized calcium silicate-and hydroxyapatite-based bioactive materials: In vivo study. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 145(7-8), 370-377.
https://doi.org/10.2298/SARH160719063O

Opačić-Galić V, Petrović V, Jokanović V, Živković S. Histological evaluation of tissue reactions to newly synthetized calcium silicate-and hydroxyapatite-based bioactive materials: In vivo study. in Srpski arhiv za celokupno lekarstvo. 2017;145(7-8):370-377.
doi:10.2298/SARH160719063O .

Opačić-Galić, Vanja, Petrović, Violeta, Jokanović, Vukoman, Živković, Slavoljub, "Histological evaluation of tissue reactions to newly synthetized calcium silicate-and hydroxyapatite-based bioactive materials: In vivo study" in Srpski arhiv za celokupno lekarstvo, 145, no. 7-8 (2017):370-377,
https://doi.org/10.2298/SARH160719063O . .

TY  - JOUR
AU  - Popović-Bajić, Marijana
AU  - Petrović, Violeta
AU  - Opačić-Galić, Vanja
AU  - Danilović, Vesna
AU  - Jokanović, Vukoman
AU  - Prokić, Branislav
AU  - Bolka-Prokić, Bogomir
AU  - Živković, Slavoljub
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2101
AB  - Introduction Direct pulp capping is an important therapeutic method that has goal to provide formation of dentin bridge and healing process of the pulp. The aim of this study was to investigate the effects of new nanostructural materials based on calcium silicate systems and hydroxyapatite on exposed dental pulp in Vietnamese pigs. Material and Methods The study was conducted on 30 teeth of two Vietnamese pigs (Sus scrofa verus). On buccal surfaces of incisors, canines and first premolars, class V cavities were prepared with a small round bur and pulp horn was exposed. In the first experimental group (10 teeth) the perforation was covered with new nanostructural material based on calcium silicate systems (CS). In the second experimental group, the perforation was covered with compound of calcium silicate systems and hydroxyapatite (HA-CS) (10 teeth). In the control group, exposed pulp was covered with Pro Root MTA® (Dentsply Tulsa Dental, Johnson City, TN, USA) (10 teeth). All cavities were restored with glass ionomer cement (GC Fuji VIII, GC Corporation, Tokyo, Japan). Observation period was 28 days. After sacrificing the animals, histological preparations were done to analyze the presence of dentin bridge, inflammatory reaction of the pulp, pulp tissue reorganization and the presence of bacteria. Results Dentin bridge was observed in all teeth (experimental and control groups). Inflammation of the pulp was mild to moderate in all groups. Neoangiogenesis and many odontoblast like cells responsible for dentin bridge formation were detected. Necrosis was not observed in any case, neither the presence of Gram-positive bacteria in the pulp. Conclusion Histological analysis indicated favorable therapeutic effects of new nanostructural materials based on calcium silicate systems and hydroxyapatite for direct pulp capping in teeth of Vietnamese pigs.
AB  - Uvod Direktno prekrivanje pulpe je važan terapijski postupak koji ima zadatak da obezbedi zatvaranje pulpne komore i omogući proces zarastanja. Cilj ovog rada je bio da se ispita efekat novih nanostrukturnih materijala na bazi kalcijum-silikatnih sistema i hidroksiapatita na eksponiranu pulpu zuba vijetnamskih svinja. Materijal i metode rada Istraživanje je sprovedeno na 30 zuba kod dve vijetnamske svinje (Sus scrofa verus). Na vestibularnim površinama sekutića, očnjaka i prvih premolara urađene su preparacije kaviteta V klase, pri čemu je malim okruglim svrdlom napravljena namerna eksploracija komore pulpe. U prvoj eksperimentalnoj grupi (10 zuba) perforacija je prekrivana novim nanostrukturnim materijalom na bazi kalcijum-silikatnih sistema (CS). U drugoj eksperimentalnoj grupi (10 zuba) perforacija je prekrivana smešom kalcijum-silikatnog sistema i hidroksiapatita (HA-CS). U kontrolnoj grupi (10 zuba) perforacija je prekrivana sa MTA® (Dentsply Tulsa Dental, Džonson Siti, Tenesi, SAD). Svi kaviteti su restaurirani glas-jonomer cementom (GC Fuji VIII, GC Corporation, Tokio, Japan). Opservacioni period iznosio je 28 dana. Nakon žrtvovanja životinja napravljeni su histološki preparati na kojima su analizirani postojanje dentinskog mostića, inflamatorna reakcija pulpe, reorganizacija pulpnog tkiva i prisustvo bakterija. Rezultati Na svim zubima eksperimentalnih grupa i kontrolne grupe zabeleženo je stvaranje dentinskog mostića. Zapaljenje pulpe je bilo blago do umereno i u eksperimentalnim i u kontrolnoj grupi. Uočeni su znaci neoangiogeneze i mnoštvo ćelija sličnih odontoblastima koje su odgovorne za stvaranje dentinskog mostića. Nekroza nije zabeležena ni u jednom slučaju, kao ni prisustvo gram-pozitivnih bakterija u pulpi. Zaključak Histološka analiza je ukazala na povoljne terapijske efekte novih nanostrukturnih materijala na bazi kalcijum-silikatnih sistema i hidroksiapatita u direktnom prekrivanju pulpe zuba vijetnamskih svinja.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Direct pulp capping with novel nanostructural materials based on calcium silicate systems and hydroxyapatite
T1  - Direktno prekrivanje pulpe novim nanostrukturnim materijalima na bazi kalcijum-silikatnih sistema i hidroksiapatita
VL  - 63
IS  - 4
SP  - 183
EP  - 192
DO  - 10.1515/sdj-2016-0019
ER  - 

@article{
author = "Popović-Bajić, Marijana and Petrović, Violeta and Opačić-Galić, Vanja and Danilović, Vesna and Jokanović, Vukoman and Prokić, Branislav and Bolka-Prokić, Bogomir and Živković, Slavoljub",
year = "2016",
abstract = "Introduction Direct pulp capping is an important therapeutic method that has goal to provide formation of dentin bridge and healing process of the pulp. The aim of this study was to investigate the effects of new nanostructural materials based on calcium silicate systems and hydroxyapatite on exposed dental pulp in Vietnamese pigs. Material and Methods The study was conducted on 30 teeth of two Vietnamese pigs (Sus scrofa verus). On buccal surfaces of incisors, canines and first premolars, class V cavities were prepared with a small round bur and pulp horn was exposed. In the first experimental group (10 teeth) the perforation was covered with new nanostructural material based on calcium silicate systems (CS). In the second experimental group, the perforation was covered with compound of calcium silicate systems and hydroxyapatite (HA-CS) (10 teeth). In the control group, exposed pulp was covered with Pro Root MTA® (Dentsply Tulsa Dental, Johnson City, TN, USA) (10 teeth). All cavities were restored with glass ionomer cement (GC Fuji VIII, GC Corporation, Tokyo, Japan). Observation period was 28 days. After sacrificing the animals, histological preparations were done to analyze the presence of dentin bridge, inflammatory reaction of the pulp, pulp tissue reorganization and the presence of bacteria. Results Dentin bridge was observed in all teeth (experimental and control groups). Inflammation of the pulp was mild to moderate in all groups. Neoangiogenesis and many odontoblast like cells responsible for dentin bridge formation were detected. Necrosis was not observed in any case, neither the presence of Gram-positive bacteria in the pulp. Conclusion Histological analysis indicated favorable therapeutic effects of new nanostructural materials based on calcium silicate systems and hydroxyapatite for direct pulp capping in teeth of Vietnamese pigs., Uvod Direktno prekrivanje pulpe je važan terapijski postupak koji ima zadatak da obezbedi zatvaranje pulpne komore i omogući proces zarastanja. Cilj ovog rada je bio da se ispita efekat novih nanostrukturnih materijala na bazi kalcijum-silikatnih sistema i hidroksiapatita na eksponiranu pulpu zuba vijetnamskih svinja. Materijal i metode rada Istraživanje je sprovedeno na 30 zuba kod dve vijetnamske svinje (Sus scrofa verus). Na vestibularnim površinama sekutića, očnjaka i prvih premolara urađene su preparacije kaviteta V klase, pri čemu je malim okruglim svrdlom napravljena namerna eksploracija komore pulpe. U prvoj eksperimentalnoj grupi (10 zuba) perforacija je prekrivana novim nanostrukturnim materijalom na bazi kalcijum-silikatnih sistema (CS). U drugoj eksperimentalnoj grupi (10 zuba) perforacija je prekrivana smešom kalcijum-silikatnog sistema i hidroksiapatita (HA-CS). U kontrolnoj grupi (10 zuba) perforacija je prekrivana sa MTA® (Dentsply Tulsa Dental, Džonson Siti, Tenesi, SAD). Svi kaviteti su restaurirani glas-jonomer cementom (GC Fuji VIII, GC Corporation, Tokio, Japan). Opservacioni period iznosio je 28 dana. Nakon žrtvovanja životinja napravljeni su histološki preparati na kojima su analizirani postojanje dentinskog mostića, inflamatorna reakcija pulpe, reorganizacija pulpnog tkiva i prisustvo bakterija. Rezultati Na svim zubima eksperimentalnih grupa i kontrolne grupe zabeleženo je stvaranje dentinskog mostića. Zapaljenje pulpe je bilo blago do umereno i u eksperimentalnim i u kontrolnoj grupi. Uočeni su znaci neoangiogeneze i mnoštvo ćelija sličnih odontoblastima koje su odgovorne za stvaranje dentinskog mostića. Nekroza nije zabeležena ni u jednom slučaju, kao ni prisustvo gram-pozitivnih bakterija u pulpi. Zaključak Histološka analiza je ukazala na povoljne terapijske efekte novih nanostrukturnih materijala na bazi kalcijum-silikatnih sistema i hidroksiapatita u direktnom prekrivanju pulpe zuba vijetnamskih svinja.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Direct pulp capping with novel nanostructural materials based on calcium silicate systems and hydroxyapatite, Direktno prekrivanje pulpe novim nanostrukturnim materijalima na bazi kalcijum-silikatnih sistema i hidroksiapatita",
volume = "63",
number = "4",
pages = "183-192",
doi = "10.1515/sdj-2016-0019"
}

Popović-Bajić, M., Petrović, V., Opačić-Galić, V., Danilović, V., Jokanović, V., Prokić, B., Bolka-Prokić, B.,& Živković, S.. (2016). Direct pulp capping with novel nanostructural materials based on calcium silicate systems and hydroxyapatite. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 63(4), 183-192.
https://doi.org/10.1515/sdj-2016-0019

Popović-Bajić M, Petrović V, Opačić-Galić V, Danilović V, Jokanović V, Prokić B, Bolka-Prokić B, Živković S. Direct pulp capping with novel nanostructural materials based on calcium silicate systems and hydroxyapatite. in Stomatološki glasnik Srbije. 2016;63(4):183-192.
doi:10.1515/sdj-2016-0019 .

Popović-Bajić, Marijana, Petrović, Violeta, Opačić-Galić, Vanja, Danilović, Vesna, Jokanović, Vukoman, Prokić, Branislav, Bolka-Prokić, Bogomir, Živković, Slavoljub, "Direct pulp capping with novel nanostructural materials based on calcium silicate systems and hydroxyapatite" in Stomatološki glasnik Srbije, 63, no. 4 (2016):183-192,
https://doi.org/10.1515/sdj-2016-0019 . .

TY  - JOUR
AU  - Petrović, Violeta
AU  - Opačić-Galić, Vanja
AU  - Dželetović, Bojan
AU  - Jokanović, Vukoman
AU  - Živković, Slavoljub
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2068
AB  - Introduction Calcium silicate cements can be successfully used for the treatment of root perforations due to their exceptional biological and sealing properties. The aim of this study was to test, using dye penetration method, marginal microleakage of newly synthesized nanostructured biomaterials based on calcium silicate system and hydroxyapatite after their application in interradicular perforation of extracted teeth. Material and Methods The study included 34 extracted human molars. Newly synthesized nanostructured materials: one based on calcium silicate system (CS), and the other one based on hydroxyapatite and active calcium silicate system (HA-CS) were tested. Mineral trioxide agreaggate (MTA; Angelus, Londrina, Brazil) was used as control. Marginal microleakage was evaluated using dye penetration test 6 months after the application of materials in experimentally prepared inter-radicular perforations in extracted human molars. Dye penetration was analyzed using light microscope at 30X magnification, a method of quantifying visual information in computer software for image processing (Adobe Photoshop CS5 Extended, version 12.0 x 32). The values were expressed in millimeters, and the results statistically analyzed using one-way ANOVA and Tukey post-hoc test (α=0.05). Results The shortest dye penetration was measured for calcium silicate system (0.44 mm), while slightly higher values were found for MTA (0.54 mm). Dye penetration for hydroxyapatite and active calcium silicate system (2.00 mm) was longer than for the other two materials (p lt 0.05). Conclusion The lowest marginal microleakage was observed in CS and was comparable to MTA. Microleakage in HA-CS was significantly higher than CS and MTA.
AB  - Uvod Primena cemenata od kalcijum-silikata u lečenju perforacija korena zuba zasniva se na njihovim izuzetnim biološkim svojstvima i odgovarajućem rubnom zaptivanju. Cilj ovog rada bio je da se testom prodora boje ispita marginalna mikropropustljivost novosintetisanih nanostrukturnih biomaterijala na bazi kalcijumsilikatnih sistema i hidroksiapatita nakon primene materijala u interradiksne perforacije ekstrahovanih zuba. Materijal i metode rada Ispitivanje je realizovano na 34 ekstrahovana humana molara. Testirani su novosintetisani nanostrukturni materijali: materijal na bazi aktivnih kalcijumsilikatnih sistema (CS) i materijal na bazi hidroksiapatita i aktivnih kalcijumsilikatnih sistema (HA-CS). Kao kontrolni materijal korišćen je komercijalni kalcijumsilikatni cement (MTA Angelus, Londrina, Brazil). Marginalna mikropropustljivost je ispitivana testom prodora boje šest meseci nakon primene materijala u eksperimentalno preparisane interradiksne perforacije na ekstrahovanim humanim molarima. Prodor boje je analiziran svetlosnim mikroskopom na uveličanju od 30 puta metodom kvantifikovanja vizuelnih informacija kompjuterskim programom za obradu slike (Adobe Photoshop CS5 Extended, verzija 12.0x32). Dobijene vrednosti su izražene u milimetrima, a dobijeni rezultati statistički su obrađeni primenom jednofaktorskog testa ANOVA sa Tukijevim (Tukey) post-hoc testom (α=0,05). Rezultati Najmanji prodor boje izmeren je kod materijala CS (0,44 mm), dok su nešto veće vrednosti zabeležene kod MTA (0,54 mm). Prodor boje kod materijala HA-CS (2,00 mm) bio je značajno veći u odnosu na materijale CS i MTA (p lt 0,05). Zaključak Najmanja marginalna mikropropustljivost zabeležena je kod materijala CS i bila je komparabilna sa MTA. Mikropropustljivost materijala HA-CS bila je značajno veća u odnosu na materijal CS i kontrolni materijal MTA.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Marginal microleakage of newly synthesized nanostructured biomaterials based on active calcium silicate systems and hydroxyapatite
T1  - Ispitivanje marginalne mikropropustljivosti novosintetisanih nanostrukturnih biomaterijala na bazi aktivnih kalcijum silikatnih sistema i hidroksiapatita
VL  - 62
IS  - 3
SP  - 109
EP  - 116
DO  - 10.1515/sdj-2015-0011
ER  - 

@article{
author = "Petrović, Violeta and Opačić-Galić, Vanja and Dželetović, Bojan and Jokanović, Vukoman and Živković, Slavoljub",
year = "2015",
abstract = "Introduction Calcium silicate cements can be successfully used for the treatment of root perforations due to their exceptional biological and sealing properties. The aim of this study was to test, using dye penetration method, marginal microleakage of newly synthesized nanostructured biomaterials based on calcium silicate system and hydroxyapatite after their application in interradicular perforation of extracted teeth. Material and Methods The study included 34 extracted human molars. Newly synthesized nanostructured materials: one based on calcium silicate system (CS), and the other one based on hydroxyapatite and active calcium silicate system (HA-CS) were tested. Mineral trioxide agreaggate (MTA; Angelus, Londrina, Brazil) was used as control. Marginal microleakage was evaluated using dye penetration test 6 months after the application of materials in experimentally prepared inter-radicular perforations in extracted human molars. Dye penetration was analyzed using light microscope at 30X magnification, a method of quantifying visual information in computer software for image processing (Adobe Photoshop CS5 Extended, version 12.0 x 32). The values were expressed in millimeters, and the results statistically analyzed using one-way ANOVA and Tukey post-hoc test (α=0.05). Results The shortest dye penetration was measured for calcium silicate system (0.44 mm), while slightly higher values were found for MTA (0.54 mm). Dye penetration for hydroxyapatite and active calcium silicate system (2.00 mm) was longer than for the other two materials (p lt 0.05). Conclusion The lowest marginal microleakage was observed in CS and was comparable to MTA. Microleakage in HA-CS was significantly higher than CS and MTA., Uvod Primena cemenata od kalcijum-silikata u lečenju perforacija korena zuba zasniva se na njihovim izuzetnim biološkim svojstvima i odgovarajućem rubnom zaptivanju. Cilj ovog rada bio je da se testom prodora boje ispita marginalna mikropropustljivost novosintetisanih nanostrukturnih biomaterijala na bazi kalcijumsilikatnih sistema i hidroksiapatita nakon primene materijala u interradiksne perforacije ekstrahovanih zuba. Materijal i metode rada Ispitivanje je realizovano na 34 ekstrahovana humana molara. Testirani su novosintetisani nanostrukturni materijali: materijal na bazi aktivnih kalcijumsilikatnih sistema (CS) i materijal na bazi hidroksiapatita i aktivnih kalcijumsilikatnih sistema (HA-CS). Kao kontrolni materijal korišćen je komercijalni kalcijumsilikatni cement (MTA Angelus, Londrina, Brazil). Marginalna mikropropustljivost je ispitivana testom prodora boje šest meseci nakon primene materijala u eksperimentalno preparisane interradiksne perforacije na ekstrahovanim humanim molarima. Prodor boje je analiziran svetlosnim mikroskopom na uveličanju od 30 puta metodom kvantifikovanja vizuelnih informacija kompjuterskim programom za obradu slike (Adobe Photoshop CS5 Extended, verzija 12.0x32). Dobijene vrednosti su izražene u milimetrima, a dobijeni rezultati statistički su obrađeni primenom jednofaktorskog testa ANOVA sa Tukijevim (Tukey) post-hoc testom (α=0,05). Rezultati Najmanji prodor boje izmeren je kod materijala CS (0,44 mm), dok su nešto veće vrednosti zabeležene kod MTA (0,54 mm). Prodor boje kod materijala HA-CS (2,00 mm) bio je značajno veći u odnosu na materijale CS i MTA (p lt 0,05). Zaključak Najmanja marginalna mikropropustljivost zabeležena je kod materijala CS i bila je komparabilna sa MTA. Mikropropustljivost materijala HA-CS bila je značajno veća u odnosu na materijal CS i kontrolni materijal MTA.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Marginal microleakage of newly synthesized nanostructured biomaterials based on active calcium silicate systems and hydroxyapatite, Ispitivanje marginalne mikropropustljivosti novosintetisanih nanostrukturnih biomaterijala na bazi aktivnih kalcijum silikatnih sistema i hidroksiapatita",
volume = "62",
number = "3",
pages = "109-116",
doi = "10.1515/sdj-2015-0011"
}

Petrović, V., Opačić-Galić, V., Dželetović, B., Jokanović, V.,& Živković, S.. (2015). Marginal microleakage of newly synthesized nanostructured biomaterials based on active calcium silicate systems and hydroxyapatite. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 62(3), 109-116.
https://doi.org/10.1515/sdj-2015-0011

Petrović V, Opačić-Galić V, Dželetović B, Jokanović V, Živković S. Marginal microleakage of newly synthesized nanostructured biomaterials based on active calcium silicate systems and hydroxyapatite. in Stomatološki glasnik Srbije. 2015;62(3):109-116.
doi:10.1515/sdj-2015-0011 .

Petrović, Violeta, Opačić-Galić, Vanja, Dželetović, Bojan, Jokanović, Vukoman, Živković, Slavoljub, "Marginal microleakage of newly synthesized nanostructured biomaterials based on active calcium silicate systems and hydroxyapatite" in Stomatološki glasnik Srbije, 62, no. 3 (2015):109-116,
https://doi.org/10.1515/sdj-2015-0011 . .

TY  - THES
AU  - Petrović, Violeta
PY  - 2015
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=2850
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:11056/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=1024228750
UR  - http://nardus.mpn.gov.rs/123456789/5296
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/989
AB  - In the past two decades, significant improvement in endodontic therapy has been made by introducing new biomaterials. Beside biocompatibility, these materials are bioactive with the ability to induce cell proliferation and differentiation and tissue regeneration. The greatest attention has been given to calcium silicate cements, because of superior biological and good physical properties. Clinical use of these cements is restricted by long setting time and low wash-out resistance. Calcium phosphate cements have also been investigated, but although biocompatible, inferior mechanical properties limit their use as endodontic cements. Recently, two new nanostructural biomaterials, based on calcium silicate systems (CS) and a mixture of hydroxyapatite and calcium silicate systems (HA-CS) have been synthesized. Innovative technology provided synthesis of cements with shorter setting time compared to commercial materials with similar chemical constitution. Also, cements CS and HA-CS have been chemically modified in an attempt to synthesize canal sealers with better fluidity and longer setting time. The purpose of this study was to evaluate physical and biological properties of the new nanostructural biomaterials based on calcium silicate systems (CS) and a mixture of hydroxyapatite and calcium silicate systems (HA-CS). Solubility and porosity of a experimental materials CS and HA-CS were measured after 28 days of immersion in simulated tissue fluid. Solubility and porosity of experimental CS and HA-CS sealers were measured after 24 h of immersion in simulated tissue fluid. Marginal microleakage of materials CS and HA-CS was evaluated by the dye penetration method, six months after material application in furcal perforations of extracted teeth. Bond strength to dentin of materials CS and HA-CS and sealers CS and HA-CS, was measured by the push-out test...
AB  - Tokom prethodne dve decenije, ostvaren je značajan napredak u oblasti endodontske terapije uvođenjem novih biomaterijala, superniornih osobina u odnosu na konvencionalne materijale. Biomaterijale, pored biokompatibilnosti odlikuje i bioaktivnost odnosno sposobnost indukcije ćelijske diferencijacije i proliferacije koja omogućava regeneraciju tkiva. Najznačajniji među novim materijalima su svakako kalcijum silikatni cementi sa izuzetnim biološkim i adekvatnim fizičkim svojstvima. Ipak, kliničku primenu ovih materijala otežava dugo vreme vezivanja i ispiranje sa mesta aplikacije. Kalcijum fosfatni cementi su takođe predmet brojnih istraživanja, ali se i pored biokompatibilnosti, usled loših mehaničkih svojstava, ne mogu samostalno koristiti u svojstvu endodontskih cemenata. U cilju prevazilaženja negativnih svojstava kalcijum silikatnih i kalcijum fosfatnih cemenata, inovativnom tehnologijom sintetisana su dva nanostrukturna biomaterijala na bazi kalcijum silikatnih sistema (CS) i mešavine hidroksiapatita i kalcijumsilikatnih sistema (HA-CS). Unapređenom tehnologijom dobijeni su materijali izražene aktivnosti čestica, sa značajno kraćim vremenom vezivanja u odnosu na komercijalno dostupne materijale sličnog hemijskog sastava. Osnovne formulacije materijala CS i HA-CS, su potom hemijski modifikovane, u cilju dobijanja kanalnih silera, fluidnije konzistencije i dužeg vremena vezivanja. Cilj ovog istraživanja je bio da se ispitaju fizička i biološka svojstva novosintetisanih nanostrukturnih biomaterijala na bazi aktivnih kalcijumsilikatnih sistema (CS) i mešavine hidroksiapatita i kalcijumsilikatnih sistema (HA-CS). Rastvorljivost i poroznost osnovnih formulacija eksperimentalnih materijala CS i HA-CS ispitivana je merenjem promena u masi uzoraka materijala nakon čuvanja uzoraka tokom 28 dana u veštačkom tkivnom fluidu...
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Evaluation of biological and physical properties of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite
T1  - Ispitivanje bioloških i fizičkih svojstava nanostrukturnih biomaterijala na bazi aktivnih kalcijumsilikatnih sistema i hidroksiapatita
UR  - https://hdl.handle.net/21.15107/rcub_nardus_5296
ER  - 

@phdthesis{
author = "Petrović, Violeta",
year = "2015",
abstract = "In the past two decades, significant improvement in endodontic therapy has been made by introducing new biomaterials. Beside biocompatibility, these materials are bioactive with the ability to induce cell proliferation and differentiation and tissue regeneration. The greatest attention has been given to calcium silicate cements, because of superior biological and good physical properties. Clinical use of these cements is restricted by long setting time and low wash-out resistance. Calcium phosphate cements have also been investigated, but although biocompatible, inferior mechanical properties limit their use as endodontic cements. Recently, two new nanostructural biomaterials, based on calcium silicate systems (CS) and a mixture of hydroxyapatite and calcium silicate systems (HA-CS) have been synthesized. Innovative technology provided synthesis of cements with shorter setting time compared to commercial materials with similar chemical constitution. Also, cements CS and HA-CS have been chemically modified in an attempt to synthesize canal sealers with better fluidity and longer setting time. The purpose of this study was to evaluate physical and biological properties of the new nanostructural biomaterials based on calcium silicate systems (CS) and a mixture of hydroxyapatite and calcium silicate systems (HA-CS). Solubility and porosity of a experimental materials CS and HA-CS were measured after 28 days of immersion in simulated tissue fluid. Solubility and porosity of experimental CS and HA-CS sealers were measured after 24 h of immersion in simulated tissue fluid. Marginal microleakage of materials CS and HA-CS was evaluated by the dye penetration method, six months after material application in furcal perforations of extracted teeth. Bond strength to dentin of materials CS and HA-CS and sealers CS and HA-CS, was measured by the push-out test..., Tokom prethodne dve decenije, ostvaren je značajan napredak u oblasti endodontske terapije uvođenjem novih biomaterijala, superniornih osobina u odnosu na konvencionalne materijale. Biomaterijale, pored biokompatibilnosti odlikuje i bioaktivnost odnosno sposobnost indukcije ćelijske diferencijacije i proliferacije koja omogućava regeneraciju tkiva. Najznačajniji među novim materijalima su svakako kalcijum silikatni cementi sa izuzetnim biološkim i adekvatnim fizičkim svojstvima. Ipak, kliničku primenu ovih materijala otežava dugo vreme vezivanja i ispiranje sa mesta aplikacije. Kalcijum fosfatni cementi su takođe predmet brojnih istraživanja, ali se i pored biokompatibilnosti, usled loših mehaničkih svojstava, ne mogu samostalno koristiti u svojstvu endodontskih cemenata. U cilju prevazilaženja negativnih svojstava kalcijum silikatnih i kalcijum fosfatnih cemenata, inovativnom tehnologijom sintetisana su dva nanostrukturna biomaterijala na bazi kalcijum silikatnih sistema (CS) i mešavine hidroksiapatita i kalcijumsilikatnih sistema (HA-CS). Unapređenom tehnologijom dobijeni su materijali izražene aktivnosti čestica, sa značajno kraćim vremenom vezivanja u odnosu na komercijalno dostupne materijale sličnog hemijskog sastava. Osnovne formulacije materijala CS i HA-CS, su potom hemijski modifikovane, u cilju dobijanja kanalnih silera, fluidnije konzistencije i dužeg vremena vezivanja. Cilj ovog istraživanja je bio da se ispitaju fizička i biološka svojstva novosintetisanih nanostrukturnih biomaterijala na bazi aktivnih kalcijumsilikatnih sistema (CS) i mešavine hidroksiapatita i kalcijumsilikatnih sistema (HA-CS). Rastvorljivost i poroznost osnovnih formulacija eksperimentalnih materijala CS i HA-CS ispitivana je merenjem promena u masi uzoraka materijala nakon čuvanja uzoraka tokom 28 dana u veštačkom tkivnom fluidu...",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Evaluation of biological and physical properties of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite, Ispitivanje bioloških i fizičkih svojstava nanostrukturnih biomaterijala na bazi aktivnih kalcijumsilikatnih sistema i hidroksiapatita",
url = "https://hdl.handle.net/21.15107/rcub_nardus_5296"
}

Petrović, V.. (2015). Evaluation of biological and physical properties of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_nardus_5296

Petrović V. Evaluation of biological and physical properties of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite. 2015;.
https://hdl.handle.net/21.15107/rcub_nardus_5296 .

Petrović, Violeta, "Evaluation of biological and physical properties of nanostructural biomaterials based on active calcium silicate systems and hydroxyapatite" (2015),
https://hdl.handle.net/21.15107/rcub_nardus_5296 .

TY  - JOUR
AU  - Jokanović, Vukoman
AU  - Čolović, Božana
AU  - Živković-Sandić, Marija
AU  - Petrović, Violeta
AU  - Živković, Slavoljub
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1867
AB  - Calcium phosphates, together with polymers, are most commonly used materials in bone engineering since their composition is similar to bone. They are used to fulfill various defects caused by injury or bone disease, as well as for the preparation of endodontic mixtures. Because of their great importance in dentistry, these materials are given special attention in the current paper. This paper is a part of the monograph entitled 'Nanomedicine, the Greatest Challenge of the 21st Century', which attracted great interest of technical and professional communities in different areas of medicine. Also for the last two years this book is promoted by the Student Cultural Centre as the only national book chosen in the narrowest election. That fact is very important for young researchers who study tissue engineering, endodontics and implantology.
AB  - Kalcijum- fosfati, zajedno s nekim polimerima, najviše su korišćeni materijali u inženjerstvu koštanog tkiva, budući da su po sastavu bliski prirodnoj kosti. Koriste se za ispune različitih oštećenja nastalih usled povreda ili bolesti koštanog tkiva, kao i za pripremu endodontskih mešavina za primenu u stomatologiji. Zbog izuzetnog značaja u stomatologiji, kalcijumfosfatni materijali zaslužuju posebno mesto, pa će im u okviru ovog rada, ali i radova koji će uslediti, biti posvećena posebna pažnja. Radovi su najvećim delom sastavni deo monografije pod nazivom 'Nanomedicina, najveći izazov 21. veka', koja je pobudila veliko interesovanje stručne i profesionalne javnosti usmerene ka različitim oblastima medicine i koju je već dve godine zaredom Studentski kulturni centar, kao jedinu knjigu domaćeg autora, promovisao kao knjigu najužeg izbora. Verujemo da je ta činjenica posebno važna za mlađe istraživače koji se bave problemima inženjerstva tkiva, endodoncijom i implantologijom.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Calcium phosphate materials in bone tissue engineering
T1  - Kalcijumfosfatni materijali u inženjerstvu koštanog tkiva
VL  - 61
IS  - 2
SP  - 93
EP  - 101
DO  - 10.2298/sgs1402093j
ER  - 

@article{
author = "Jokanović, Vukoman and Čolović, Božana and Živković-Sandić, Marija and Petrović, Violeta and Živković, Slavoljub",
year = "2014",
abstract = "Calcium phosphates, together with polymers, are most commonly used materials in bone engineering since their composition is similar to bone. They are used to fulfill various defects caused by injury or bone disease, as well as for the preparation of endodontic mixtures. Because of their great importance in dentistry, these materials are given special attention in the current paper. This paper is a part of the monograph entitled 'Nanomedicine, the Greatest Challenge of the 21st Century', which attracted great interest of technical and professional communities in different areas of medicine. Also for the last two years this book is promoted by the Student Cultural Centre as the only national book chosen in the narrowest election. That fact is very important for young researchers who study tissue engineering, endodontics and implantology., Kalcijum- fosfati, zajedno s nekim polimerima, najviše su korišćeni materijali u inženjerstvu koštanog tkiva, budući da su po sastavu bliski prirodnoj kosti. Koriste se za ispune različitih oštećenja nastalih usled povreda ili bolesti koštanog tkiva, kao i za pripremu endodontskih mešavina za primenu u stomatologiji. Zbog izuzetnog značaja u stomatologiji, kalcijumfosfatni materijali zaslužuju posebno mesto, pa će im u okviru ovog rada, ali i radova koji će uslediti, biti posvećena posebna pažnja. Radovi su najvećim delom sastavni deo monografije pod nazivom 'Nanomedicina, najveći izazov 21. veka', koja je pobudila veliko interesovanje stručne i profesionalne javnosti usmerene ka različitim oblastima medicine i koju je već dve godine zaredom Studentski kulturni centar, kao jedinu knjigu domaćeg autora, promovisao kao knjigu najužeg izbora. Verujemo da je ta činjenica posebno važna za mlađe istraživače koji se bave problemima inženjerstva tkiva, endodoncijom i implantologijom.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Calcium phosphate materials in bone tissue engineering, Kalcijumfosfatni materijali u inženjerstvu koštanog tkiva",
volume = "61",
number = "2",
pages = "93-101",
doi = "10.2298/sgs1402093j"
}

Jokanović, V., Čolović, B., Živković-Sandić, M., Petrović, V.,& Živković, S.. (2014). Calcium phosphate materials in bone tissue engineering. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 61(2), 93-101.
https://doi.org/10.2298/sgs1402093j

Jokanović V, Čolović B, Živković-Sandić M, Petrović V, Živković S. Calcium phosphate materials in bone tissue engineering. in Stomatološki glasnik Srbije. 2014;61(2):93-101.
doi:10.2298/sgs1402093j .

Jokanović, Vukoman, Čolović, Božana, Živković-Sandić, Marija, Petrović, Violeta, Živković, Slavoljub, "Calcium phosphate materials in bone tissue engineering" in Stomatološki glasnik Srbije, 61, no. 2 (2014):93-101,
https://doi.org/10.2298/sgs1402093j . .

TY  - JOUR
AU  - Petrović, Violeta
AU  - Opačić-Galić, Vanja
AU  - Jokanović, Vukoman
AU  - Jovanović, M.
AU  - Basta-Jovanović, Gordana
AU  - Živković, Slavoljub
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1708
AB  - The aim of the study was to investigate rat connective tissue response to a new calcium silicate system 7, 15, 30 and 60 days after implantation. Twenty Wistar albino male rats received two tubes half-filled with a new calcium silicate system (NCSS) or MTA in subcutaneous tissue. The empty half of the tubes served as controls. Five animals were sacrificed after 7, 15, 30 and 60 days and samples of the subcutaneous tissue around implanted material were submitted to histological analysis. The intensity of inflammation was evaluated based on the number of inflammatory cells present. Statistical analysis was performed using one way ANOVA and Holm Sidak's multiple comparison tests. Mild to moderate inflammatory reaction was observed after 7, 15 and 30 days around a NCSS while mild inflammatory reaction was detected after 60 days of implantation. In the MTA group, mild to moderate inflammatory reaction was found after 7 and 15 days while mild inflammatory reaction was present after 30 and 60 days. There was no statistically significant difference in the intensity of inflammatory reactions between the tested materials and control groups in any experimental period (ANOVA p>0.05). Regarding the intensity of inflammatory reactions at different experimental periods, a statistically significant difference was observed between 7 and 30 days, 7 and 60 days and 15 to 60 days for both materials. For the controls, a statistically significant difference was found between 7 and 60 days and 15 and 60 days of the experiment (Holm Sidak  lt  p 0.001). Subcutaneous tissue of rats showed good tolerance to a new calcium silicate system. Inflammatory reaction was similar to that caused by MTA.
AB  - Cilj ovog rada je bio da se ispita biokompatibilnost novog kalcijum silikatnog sistema nakon in vivo implantacije u potkožno tkivo pacova. Istraživanje je obuhvatilo 20 Wistar albino pacova muškog pola. U svaku životinju implantirane su dve tube do pola ispunjene novim kalcijum silikatnim sistemom (NCSS) odnosno MTA-om. Prazne polovine tuba služile su kao kontrola. Po 5 životinja žrtvovano je nakon 7, 15, 30 i 60 dana, nakon čega su uzorci potkožnog tkiva oko implantiranog materijala pripremljeni za histološku analizu. Intezitet zapaljenske reakcije je procenjivan na osnovu broja prisutnih ćelija zapaljenja. Statistička analiza je urađena ANOVA testom i Holm Sidak-ovim testom višestruke komparacije. U eksperimentalnim periodima 7, 15 i 30 dana u NCSS grupi je uočena blaga do umerena zapaljenska reakcija, a nakon 60 dana samo blaga zapaljenska reakcija. UMTA grupi, nakon 7 i 15 dana uočena je blaga do umerena zapaljenska reakcija, a nakon 30 i 60 dana blaga zapaljenska reakcija. Nije bilo statistički značajne razlike u intezitetu zapaljenske reakcije između testiranih materijala i kontrolne grupe ni u jednom eksperimentalnom periodu (ANOVA p>0.05). Poređenjem inteziteta zapaljenskih reakcija u različitim eksperimentalnim periodima, uočeno je postojanje statistički značajnih razlika kod oba testirana materijala između 7 i 30 dana, 7 i 60 dana kao i između 15 i 60 dana, a kod kontrole između 7 i 60 dana i 15 i 60 dana eksperimenta (Holm Sidak p  lt  0.001). Novi kalcijum silikatni sistem je pokazao biokompatibilno ponašanje. Inflamatorne reakcije potkožnog tkiva bile su slične onima koje je izazvao MTA.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria
T1  - Biocompatibility of a new nanomaterial based on calcium silicate implanted in subcutaneous connective tissue of rats
T1  - Ispitivanje biokompatibilnosti novog nanostrukturalnog materijala na bazi kalcijum silikatnih sistema implantiranjem u potkožno tkivo pacova
VL  - 62
IS  - 5-6
SP  - 697
EP  - 708
DO  - 10.2298/AVB1206697P
ER  - 

@article{
author = "Petrović, Violeta and Opačić-Galić, Vanja and Jokanović, Vukoman and Jovanović, M. and Basta-Jovanović, Gordana and Živković, Slavoljub",
year = "2012",
abstract = "The aim of the study was to investigate rat connective tissue response to a new calcium silicate system 7, 15, 30 and 60 days after implantation. Twenty Wistar albino male rats received two tubes half-filled with a new calcium silicate system (NCSS) or MTA in subcutaneous tissue. The empty half of the tubes served as controls. Five animals were sacrificed after 7, 15, 30 and 60 days and samples of the subcutaneous tissue around implanted material were submitted to histological analysis. The intensity of inflammation was evaluated based on the number of inflammatory cells present. Statistical analysis was performed using one way ANOVA and Holm Sidak's multiple comparison tests. Mild to moderate inflammatory reaction was observed after 7, 15 and 30 days around a NCSS while mild inflammatory reaction was detected after 60 days of implantation. In the MTA group, mild to moderate inflammatory reaction was found after 7 and 15 days while mild inflammatory reaction was present after 30 and 60 days. There was no statistically significant difference in the intensity of inflammatory reactions between the tested materials and control groups in any experimental period (ANOVA p>0.05). Regarding the intensity of inflammatory reactions at different experimental periods, a statistically significant difference was observed between 7 and 30 days, 7 and 60 days and 15 to 60 days for both materials. For the controls, a statistically significant difference was found between 7 and 60 days and 15 and 60 days of the experiment (Holm Sidak  lt  p 0.001). Subcutaneous tissue of rats showed good tolerance to a new calcium silicate system. Inflammatory reaction was similar to that caused by MTA., Cilj ovog rada je bio da se ispita biokompatibilnost novog kalcijum silikatnog sistema nakon in vivo implantacije u potkožno tkivo pacova. Istraživanje je obuhvatilo 20 Wistar albino pacova muškog pola. U svaku životinju implantirane su dve tube do pola ispunjene novim kalcijum silikatnim sistemom (NCSS) odnosno MTA-om. Prazne polovine tuba služile su kao kontrola. Po 5 životinja žrtvovano je nakon 7, 15, 30 i 60 dana, nakon čega su uzorci potkožnog tkiva oko implantiranog materijala pripremljeni za histološku analizu. Intezitet zapaljenske reakcije je procenjivan na osnovu broja prisutnih ćelija zapaljenja. Statistička analiza je urađena ANOVA testom i Holm Sidak-ovim testom višestruke komparacije. U eksperimentalnim periodima 7, 15 i 30 dana u NCSS grupi je uočena blaga do umerena zapaljenska reakcija, a nakon 60 dana samo blaga zapaljenska reakcija. UMTA grupi, nakon 7 i 15 dana uočena je blaga do umerena zapaljenska reakcija, a nakon 30 i 60 dana blaga zapaljenska reakcija. Nije bilo statistički značajne razlike u intezitetu zapaljenske reakcije između testiranih materijala i kontrolne grupe ni u jednom eksperimentalnom periodu (ANOVA p>0.05). Poređenjem inteziteta zapaljenskih reakcija u različitim eksperimentalnim periodima, uočeno je postojanje statistički značajnih razlika kod oba testirana materijala između 7 i 30 dana, 7 i 60 dana kao i između 15 i 60 dana, a kod kontrole između 7 i 60 dana i 15 i 60 dana eksperimenta (Holm Sidak p  lt  0.001). Novi kalcijum silikatni sistem je pokazao biokompatibilno ponašanje. Inflamatorne reakcije potkožnog tkiva bile su slične onima koje je izazvao MTA.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "Biocompatibility of a new nanomaterial based on calcium silicate implanted in subcutaneous connective tissue of rats, Ispitivanje biokompatibilnosti novog nanostrukturalnog materijala na bazi kalcijum silikatnih sistema implantiranjem u potkožno tkivo pacova",
volume = "62",
number = "5-6",
pages = "697-708",
doi = "10.2298/AVB1206697P"
}

Petrović, V., Opačić-Galić, V., Jokanović, V., Jovanović, M., Basta-Jovanović, G.,& Živković, S.. (2012). Biocompatibility of a new nanomaterial based on calcium silicate implanted in subcutaneous connective tissue of rats. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 62(5-6), 697-708.
https://doi.org/10.2298/AVB1206697P

Petrović V, Opačić-Galić V, Jokanović V, Jovanović M, Basta-Jovanović G, Živković S. Biocompatibility of a new nanomaterial based on calcium silicate implanted in subcutaneous connective tissue of rats. in Acta veterinaria. 2012;62(5-6):697-708.
doi:10.2298/AVB1206697P .

Petrović, Violeta, Opačić-Galić, Vanja, Jokanović, Vukoman, Jovanović, M., Basta-Jovanović, Gordana, Živković, Slavoljub, "Biocompatibility of a new nanomaterial based on calcium silicate implanted in subcutaneous connective tissue of rats" in Acta veterinaria, 62, no. 5-6 (2012):697-708,
https://doi.org/10.2298/AVB1206697P . .

TY  - JOUR
AU  - Petrović, Violeta
AU  - Opačić-Galić, Vanja
AU  - Živković, Slavoljub
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1671
AB  - Introduction. Postoperative pain may develop after chemomechanical preparation during endodontic treatment or retreatment. It is associated with acute apical periodontitis caused by bacteria penetrated from the root canal into the periapical tissue. The purpose of this study was to evaluate the incidence of postoperative pain during endodontic treatment after intracanal medication performed with calcium hydroxide (CH) paste or 1% chlorhexidine gel (CHX). Material and Methods. The study included 22 asymptomatic teeth in both male and female patients. Fourteen teeth had the diagnosis of pulp necrosis and the other eight were retreatment cases. The root canals were prepared by crown-down technique using K files and copious irrigation with 0.5% sodium hypochlorite (NaOCl). Intracanal dressing was performed using either calcium hydroxide paste or 1% CHX gel. Each medicament was placed in the root canals of eleven randomly selected teeth. The teeth were restored with temporary filling. Postoperative pain was registered during the seven day period between two appointments. The level of pain was rated as follows: no pain, mild pain, moderate pain and severe pain (flare-up). The obtained data was analyzed using Fisher exact test. The level of significance was α=0.05. Results. Postoperative pain was absent in 77.3% of total number of treated teeth. Severe pain (flare-up) was registered in 2 cases (9%). There was no significant difference in pain incidence between the CH paste and CHX gel group (p=0.610). Conclusion. Endodontic procedure used in this study which considered root canal instrumentation and irrigation followed by intracanal medication with CH and CHX resulted in low incidence of postoperative pain.
AB  - Uvod. Postoperacioni bol je najčešća komplikacija hemomehaničke preparacije kanala korena zuba, a posledica je akutnog zapaljenja u periradikularnom tkivu nastalog usled prodora nadražaja iz kanala korena, najčešće mikroorganizama. Cilj rada je bio da se ispita učestalost bola nakon endodontskog lečenja i ponovnog tretmana asimptomatskih zuba posle medikacije kanala korena pastom kalcijum-hidroksida (CH), odnosno gelom jednoprocentnog hlorheksidina (CHX). Materijal i metode rada. Tokom istraživanja ispitana su 22 asimptomatska zuba. Kod 14 zuba je dijagnostikovana nekroza pulpe, dok je kod osam zuba bilo potrebno uraditi ponovni tretman. Preparacija kanala korena je urađena crown-down tehnikom i K-turpijama uz obilnu irigaciju rastvorom NaOCl od 0,5%. Zubi su nasumično podeljeni u dve grupe od po 11 zuba. U prvoj grupi kanali korena su posle instrumentacije napunjeni CH pastom, a u drugoj grupi je za medikaciju kanala korišćen CHX gel. Nakon toga zubi su privremeno zatvoreni, a pojava bola je praćena do naredne posete posle sedam dana. Intenzitet bola je rangiran po sledećoj skali: bez bola, blag bol, umeren bol i jak (neizdržljiv) bol. Dobijeni podaci su statistički obrađeni primenom Fišerovog testa na nivou značajnosti od α=0,05. Rezultati. U 17 zuba (77,3%) nije bilo postoperacionog bola. Među pacijentima koji su osećali bolove jak bol je zabeležen u dva slučaja (9%). Nisu uočene statistički značajne razlike u učestalosti bola u zavisnosti od korišćenog intrakanalnog medikamenta (p=0,610). Zaključak. Endodontski postupci primenjeni u ovom istraživanju, zasnovani na temeljnoj instrumentaciji uz irigaciju rastvorom NaOCl i interseansnoj medikaciji kanala CH pastom, odnosno CHX gelom, doveli su do male incidencije postoperacionog bola.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Postoperative pain after primary endodontic treatment and retreatment of asymptomatic teeth
T1  - Učestalost bola posle endodontskog lečenja i ponovnog tretmana asimptomatskih zuba
VL  - 58
IS  - 2
SP  - 75
EP  - 81
DO  - 10.2298/SGS1102075P
ER  - 

@article{
author = "Petrović, Violeta and Opačić-Galić, Vanja and Živković, Slavoljub",
year = "2011",
abstract = "Introduction. Postoperative pain may develop after chemomechanical preparation during endodontic treatment or retreatment. It is associated with acute apical periodontitis caused by bacteria penetrated from the root canal into the periapical tissue. The purpose of this study was to evaluate the incidence of postoperative pain during endodontic treatment after intracanal medication performed with calcium hydroxide (CH) paste or 1% chlorhexidine gel (CHX). Material and Methods. The study included 22 asymptomatic teeth in both male and female patients. Fourteen teeth had the diagnosis of pulp necrosis and the other eight were retreatment cases. The root canals were prepared by crown-down technique using K files and copious irrigation with 0.5% sodium hypochlorite (NaOCl). Intracanal dressing was performed using either calcium hydroxide paste or 1% CHX gel. Each medicament was placed in the root canals of eleven randomly selected teeth. The teeth were restored with temporary filling. Postoperative pain was registered during the seven day period between two appointments. The level of pain was rated as follows: no pain, mild pain, moderate pain and severe pain (flare-up). The obtained data was analyzed using Fisher exact test. The level of significance was α=0.05. Results. Postoperative pain was absent in 77.3% of total number of treated teeth. Severe pain (flare-up) was registered in 2 cases (9%). There was no significant difference in pain incidence between the CH paste and CHX gel group (p=0.610). Conclusion. Endodontic procedure used in this study which considered root canal instrumentation and irrigation followed by intracanal medication with CH and CHX resulted in low incidence of postoperative pain., Uvod. Postoperacioni bol je najčešća komplikacija hemomehaničke preparacije kanala korena zuba, a posledica je akutnog zapaljenja u periradikularnom tkivu nastalog usled prodora nadražaja iz kanala korena, najčešće mikroorganizama. Cilj rada je bio da se ispita učestalost bola nakon endodontskog lečenja i ponovnog tretmana asimptomatskih zuba posle medikacije kanala korena pastom kalcijum-hidroksida (CH), odnosno gelom jednoprocentnog hlorheksidina (CHX). Materijal i metode rada. Tokom istraživanja ispitana su 22 asimptomatska zuba. Kod 14 zuba je dijagnostikovana nekroza pulpe, dok je kod osam zuba bilo potrebno uraditi ponovni tretman. Preparacija kanala korena je urađena crown-down tehnikom i K-turpijama uz obilnu irigaciju rastvorom NaOCl od 0,5%. Zubi su nasumično podeljeni u dve grupe od po 11 zuba. U prvoj grupi kanali korena su posle instrumentacije napunjeni CH pastom, a u drugoj grupi je za medikaciju kanala korišćen CHX gel. Nakon toga zubi su privremeno zatvoreni, a pojava bola je praćena do naredne posete posle sedam dana. Intenzitet bola je rangiran po sledećoj skali: bez bola, blag bol, umeren bol i jak (neizdržljiv) bol. Dobijeni podaci su statistički obrađeni primenom Fišerovog testa na nivou značajnosti od α=0,05. Rezultati. U 17 zuba (77,3%) nije bilo postoperacionog bola. Među pacijentima koji su osećali bolove jak bol je zabeležen u dva slučaja (9%). Nisu uočene statistički značajne razlike u učestalosti bola u zavisnosti od korišćenog intrakanalnog medikamenta (p=0,610). Zaključak. Endodontski postupci primenjeni u ovom istraživanju, zasnovani na temeljnoj instrumentaciji uz irigaciju rastvorom NaOCl i interseansnoj medikaciji kanala CH pastom, odnosno CHX gelom, doveli su do male incidencije postoperacionog bola.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Postoperative pain after primary endodontic treatment and retreatment of asymptomatic teeth, Učestalost bola posle endodontskog lečenja i ponovnog tretmana asimptomatskih zuba",
volume = "58",
number = "2",
pages = "75-81",
doi = "10.2298/SGS1102075P"
}

Petrović, V., Opačić-Galić, V.,& Živković, S.. (2011). Postoperative pain after primary endodontic treatment and retreatment of asymptomatic teeth. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 58(2), 75-81.
https://doi.org/10.2298/SGS1102075P

Petrović V, Opačić-Galić V, Živković S. Postoperative pain after primary endodontic treatment and retreatment of asymptomatic teeth. in Stomatološki glasnik Srbije. 2011;58(2):75-81.
doi:10.2298/SGS1102075P .

Petrović, Violeta, Opačić-Galić, Vanja, Živković, Slavoljub, "Postoperative pain after primary endodontic treatment and retreatment of asymptomatic teeth" in Stomatološki glasnik Srbije, 58, no. 2 (2011):75-81,
https://doi.org/10.2298/SGS1102075P . .

TY  - JOUR
AU  - Petrović, Violeta
AU  - Živković, Slavoljub
PY  - 2005
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1261
AB  - The aim of this study was to evaluate efficacy in smear layer removal of 17% EDTA and 10% citric acid, using SEM. Material and method: Twenty human, extracted teeth with a single root canal were examined. Whilst instrumentation with step-back technique and manual K files, root canals were irrigated with 2 ml of 2.5% NaOCl, between each file size. After instrumentatio n, specimens were divided into two groups. The first group was irrigated with a final flush of 17% EDTA, during one minute, and the second group was irrigated with a 10% citric acid. Results: Irrigation with 17% EDTA and 10% citric acid removed smear layer from the root canals walls. There was not statistically significant differences (p>0.05) in cleaning ability between EDTA and citric acid groups.
AB  - Cilj ovog istraživanja je bio da se pomoću SEMa proveri efikasnost 10% rastvora limunske kiseline u uklanjanju razmaznog sloja sa zidova kanala korena zuba. Materijal i metod: Istraživanje je obuhvatilo 20 jednokorenih,ekstrahovanih humanih zuba.Svi uzorci su instrumentirani step-back tehnikom i ručnim K turpijama,a tokom instrumentacije ispirani 2,5 % rastvorom NaOCla. Uzorci su zatim podeljeni u 2 eksperimentalne grupe. Prva grupa uzoraka je tokom finalnog ispiranja tretirana sa 17 % rastvorom EDTA, tokom 1 minuta,a druga grupa 10 % rastvorom limunske kiseline, po istom protokolu. Rezultati:Dobijeni rezultati su pokazali da se primenom 17 % rastvora EDTA i 10 % rastvora limunske kiseline postiže efikasno uklanjanje razmaznog sloja sa zidova kanala korena.Između ispitivanih sredstava nije bilo statistički značajne razlike (p>0.05).
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Smear layer removal with citric acid solution
T1  - Uklanjanje razmaznog sloja rastvorom limunske kiseline
VL  - 52
IS  - 4
SP  - 193
EP  - 199
DO  - 10.2298/SGS0504193P
ER  - 

@article{
author = "Petrović, Violeta and Živković, Slavoljub",
year = "2005",
abstract = "The aim of this study was to evaluate efficacy in smear layer removal of 17% EDTA and 10% citric acid, using SEM. Material and method: Twenty human, extracted teeth with a single root canal were examined. Whilst instrumentation with step-back technique and manual K files, root canals were irrigated with 2 ml of 2.5% NaOCl, between each file size. After instrumentatio n, specimens were divided into two groups. The first group was irrigated with a final flush of 17% EDTA, during one minute, and the second group was irrigated with a 10% citric acid. Results: Irrigation with 17% EDTA and 10% citric acid removed smear layer from the root canals walls. There was not statistically significant differences (p>0.05) in cleaning ability between EDTA and citric acid groups., Cilj ovog istraživanja je bio da se pomoću SEMa proveri efikasnost 10% rastvora limunske kiseline u uklanjanju razmaznog sloja sa zidova kanala korena zuba. Materijal i metod: Istraživanje je obuhvatilo 20 jednokorenih,ekstrahovanih humanih zuba.Svi uzorci su instrumentirani step-back tehnikom i ručnim K turpijama,a tokom instrumentacije ispirani 2,5 % rastvorom NaOCla. Uzorci su zatim podeljeni u 2 eksperimentalne grupe. Prva grupa uzoraka je tokom finalnog ispiranja tretirana sa 17 % rastvorom EDTA, tokom 1 minuta,a druga grupa 10 % rastvorom limunske kiseline, po istom protokolu. Rezultati:Dobijeni rezultati su pokazali da se primenom 17 % rastvora EDTA i 10 % rastvora limunske kiseline postiže efikasno uklanjanje razmaznog sloja sa zidova kanala korena.Između ispitivanih sredstava nije bilo statistički značajne razlike (p>0.05).",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Smear layer removal with citric acid solution, Uklanjanje razmaznog sloja rastvorom limunske kiseline",
volume = "52",
number = "4",
pages = "193-199",
doi = "10.2298/SGS0504193P"
}

Petrović, V.,& Živković, S.. (2005). Smear layer removal with citric acid solution. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 52(4), 193-199.
https://doi.org/10.2298/SGS0504193P

Petrović V, Živković S. Smear layer removal with citric acid solution. in Stomatološki glasnik Srbije. 2005;52(4):193-199.
doi:10.2298/SGS0504193P .

Petrović, Violeta, Živković, Slavoljub, "Smear layer removal with citric acid solution" in Stomatološki glasnik Srbije, 52, no. 4 (2005):193-199,
https://doi.org/10.2298/SGS0504193P . .