TY  - JOUR
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Evica
AU  - Mandinić, Zoran
AU  - Curcić, Marijana
AU  - Cupic-Miladinović, Dejana
AU  - Antonijević, Biljana
AU  - Matović, Vesna
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2414
AB  - Background/Aim. Fluoride has beneficial effect on dental caries prevention and enables high hardness of enamel. However, fluoride intake above optimal levels can have adverse effects on teeth and bones, especially in young children during the period of intense growth and teeth development. The aim of this study was to assess fluoride intake from water and toothpaste among 3-year-old children in Belgrade, Serbia, in the municipalities of Vracar and Novi Beograd. Methods. A questionnaire for the parents (n = 40) was used to provide information on the water consumption (tap and/or bottled water) and the brand of toothpaste used by children as well as the frequency of tooth brushing and the amount of toothpaste during brushing. Fluoride concentrations in water and toothpaste samples were determined electrochemically by using fluoride-selective electrode. Fluoride intake was estimated through a mathematical model commonly used by the U.S. Environmental Protection Agency. Results. The obtained results indicate no significant difference in daily fluoride intake through drinking water and tooth-paste in 3-year-old children in Vracar (n = 19) compared to Novi Beograd (n = 21) (p > 0.05). However, all estimated fluoride levels (0.089-0.625 mg/day) are significantly lower than the optimal daily intake level for caries protection (0.7 mg/day for children up to 4 years, FNB-USA National Institute of Medicine) and two to six times lower than tolerable upper fluoride level for the children of same age (1.3 mg/day, FNB-USA National Institute of Medicine). Furthermore, calculated daily fluoride intake per kilogram body weight confirm very low fluoride intake by water and toothpaste in children of investigated municipalities in Belgrade, being significantly below the recommended an adequate intake (0.05 mg/kg/day, EFSA). Conclusion. This preliminary study has shown that daily fluoride intake in 3-year-olds is lower than tolerable upper fluoride level, even not sufficient for the prevention of dental caries.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia
VL  - 76
IS  - 6
SP  - 607
EP  - 614
DO  - 10.2298/VSP170721136D
ER  - 

@article{
author = "Đukić-Ćosić, Danijela and Antonijević, Evica and Mandinić, Zoran and Curcić, Marijana and Cupic-Miladinović, Dejana and Antonijević, Biljana and Matović, Vesna",
year = "2019",
abstract = "Background/Aim. Fluoride has beneficial effect on dental caries prevention and enables high hardness of enamel. However, fluoride intake above optimal levels can have adverse effects on teeth and bones, especially in young children during the period of intense growth and teeth development. The aim of this study was to assess fluoride intake from water and toothpaste among 3-year-old children in Belgrade, Serbia, in the municipalities of Vracar and Novi Beograd. Methods. A questionnaire for the parents (n = 40) was used to provide information on the water consumption (tap and/or bottled water) and the brand of toothpaste used by children as well as the frequency of tooth brushing and the amount of toothpaste during brushing. Fluoride concentrations in water and toothpaste samples were determined electrochemically by using fluoride-selective electrode. Fluoride intake was estimated through a mathematical model commonly used by the U.S. Environmental Protection Agency. Results. The obtained results indicate no significant difference in daily fluoride intake through drinking water and tooth-paste in 3-year-old children in Vracar (n = 19) compared to Novi Beograd (n = 21) (p > 0.05). However, all estimated fluoride levels (0.089-0.625 mg/day) are significantly lower than the optimal daily intake level for caries protection (0.7 mg/day for children up to 4 years, FNB-USA National Institute of Medicine) and two to six times lower than tolerable upper fluoride level for the children of same age (1.3 mg/day, FNB-USA National Institute of Medicine). Furthermore, calculated daily fluoride intake per kilogram body weight confirm very low fluoride intake by water and toothpaste in children of investigated municipalities in Belgrade, being significantly below the recommended an adequate intake (0.05 mg/kg/day, EFSA). Conclusion. This preliminary study has shown that daily fluoride intake in 3-year-olds is lower than tolerable upper fluoride level, even not sufficient for the prevention of dental caries.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia",
volume = "76",
number = "6",
pages = "607-614",
doi = "10.2298/VSP170721136D"
}

Đukić-Ćosić, D., Antonijević, E., Mandinić, Z., Curcić, M., Cupic-Miladinović, D., Antonijević, B.,& Matović, V.. (2019). Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(6), 607-614.
https://doi.org/10.2298/VSP170721136D

Đukić-Ćosić D, Antonijević E, Mandinić Z, Curcić M, Cupic-Miladinović D, Antonijević B, Matović V. Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia. in Vojnosanitetski pregled. 2019;76(6):607-614.
doi:10.2298/VSP170721136D .

Đukić-Ćosić, Danijela, Antonijević, Evica, Mandinić, Zoran, Curcić, Marijana, Cupic-Miladinović, Dejana, Antonijević, Biljana, Matović, Vesna, "Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia" in Vojnosanitetski pregled, 76, no. 6 (2019):607-614,
https://doi.org/10.2298/VSP170721136D . .

TY  - JOUR
AU  - Antonijević, Evica
AU  - Mandinić, Zoran
AU  - Curcić, Marijana
AU  - Đukić-Ćosić, Danijela
AU  - Milicević, Nemanja
AU  - Ivanović, Mirjana
AU  - Carević, Momir
AU  - Antonijević, Biljana
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2170
AB  - This study explores relation between dental fluorosis occurrence in schoolchildren, residents of Ritopek, a small local community near Belgrade, and fluoride exposure via drinking water. Additionally, fluoride levels were determined in children's urine and hair samples, and efforts were made to correlate them with dental fluorosis. Dental fluorosis and caries prevalence were examined in a total of 52 schoolchildren aged 7-15 years (29 boys and 23 girls). Fluoride levels in three types of samples were analyzed using composite fluoride ion-selective electrode. Results showed high prevalence of dental fluorosis (34.6 %) and low prevalence of dental caries (23.1 %, mean DMFT 0.96) among children exposed to wide range of water fluoride levels (0.11-4.14 mg/L, n = 27). About 11 % of water samples exceeded 1.5 mg/L, a drinking-water quality guideline value for fluoride given by the World Health Organization (2006). Fluoride levels in urine and hair samples ranged between 0.07-2.59 (n = 48) and 1.07-19.83 mg/L (n = 33), respectively. Severity of dental fluorosis was positively and linearly correlated with fluoride levels in drinking water (r = 0.79). Fluoride levels in urine and hair were strongly and positively correlated with levels in drinking water (r = 0.92 and 0.94, respectively). Fluoride levels in hair samples appeared to be a potentially promising biomarker of fluoride intake via drinking water on one hand, and severity of dental fluorosis on the other hand. Based on community fluorosis index value of 0.58, dental fluorosis revealed in Ritopek can be considered as "borderline" public health issue.
PB  - Springer, Dordrecht
T2  - Environmental Geochemistry & Health
T1  - 'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren
VL  - 38
IS  - 3
SP  - 885
EP  - 896
DO  - 10.1007/s10653-015-9769-x
ER  - 

@article{
author = "Antonijević, Evica and Mandinić, Zoran and Curcić, Marijana and Đukić-Ćosić, Danijela and Milicević, Nemanja and Ivanović, Mirjana and Carević, Momir and Antonijević, Biljana",
year = "2016",
abstract = "This study explores relation between dental fluorosis occurrence in schoolchildren, residents of Ritopek, a small local community near Belgrade, and fluoride exposure via drinking water. Additionally, fluoride levels were determined in children's urine and hair samples, and efforts were made to correlate them with dental fluorosis. Dental fluorosis and caries prevalence were examined in a total of 52 schoolchildren aged 7-15 years (29 boys and 23 girls). Fluoride levels in three types of samples were analyzed using composite fluoride ion-selective electrode. Results showed high prevalence of dental fluorosis (34.6 %) and low prevalence of dental caries (23.1 %, mean DMFT 0.96) among children exposed to wide range of water fluoride levels (0.11-4.14 mg/L, n = 27). About 11 % of water samples exceeded 1.5 mg/L, a drinking-water quality guideline value for fluoride given by the World Health Organization (2006). Fluoride levels in urine and hair samples ranged between 0.07-2.59 (n = 48) and 1.07-19.83 mg/L (n = 33), respectively. Severity of dental fluorosis was positively and linearly correlated with fluoride levels in drinking water (r = 0.79). Fluoride levels in urine and hair were strongly and positively correlated with levels in drinking water (r = 0.92 and 0.94, respectively). Fluoride levels in hair samples appeared to be a potentially promising biomarker of fluoride intake via drinking water on one hand, and severity of dental fluorosis on the other hand. Based on community fluorosis index value of 0.58, dental fluorosis revealed in Ritopek can be considered as "borderline" public health issue.",
publisher = "Springer, Dordrecht",
journal = "Environmental Geochemistry & Health",
title = "'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren",
volume = "38",
number = "3",
pages = "885-896",
doi = "10.1007/s10653-015-9769-x"
}

Antonijević, E., Mandinić, Z., Curcić, M., Đukić-Ćosić, D., Milicević, N., Ivanović, M., Carević, M.,& Antonijević, B.. (2016). 'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren. in Environmental Geochemistry & Health
Springer, Dordrecht., 38(3), 885-896.
https://doi.org/10.1007/s10653-015-9769-x

Antonijević E, Mandinić Z, Curcić M, Đukić-Ćosić D, Milicević N, Ivanović M, Carević M, Antonijević B. 'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren. in Environmental Geochemistry & Health. 2016;38(3):885-896.
doi:10.1007/s10653-015-9769-x .

Antonijević, Evica, Mandinić, Zoran, Curcić, Marijana, Đukić-Ćosić, Danijela, Milicević, Nemanja, Ivanović, Mirjana, Carević, Momir, Antonijević, Biljana, "'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren" in Environmental Geochemistry & Health, 38, no. 3 (2016):885-896,
https://doi.org/10.1007/s10653-015-9769-x . .

TY  - JOUR
AU  - Mandinić, Zoran
AU  - Curcić, Marijana
AU  - Antonijević, Biljana
AU  - Carević, Momir
AU  - Mandić, Jelena
AU  - Đukić-Ćosić, Danijela
AU  - Lekić, Charles P.
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1605
AB  - In this study we determined the fluoride content in drinking water and hair of 12-year-old schoolchildren from different Serbian municipalities, i.e. Valley, Veliko Gradiste, Kacarevo and Vranjska Banja. The analyses were performed using composite fluoride ion-selective electrode. Average fluoride levels were 0.10, 0.15, 0.79 and 11 ppm in well water, 0.07, 0.10, 0.17 and 0.15 ppm in tap water, 19.3, 21.5, 25.4, and 32.5 ppm in hair samples, in Valjevo, Veliko Gradiste, Kacarevo and Vranjska Banja, respectively. Correlation analysis indicated statistically significant positive relationship between fluoride in wells water and fluoride in hair, for all municipalities: correlation coefficients were 0.54 (p lt 0.05), 0.89, 0.97 and 0.99 (p lt 0.001), in Vranjska Banja, Valjevo, Veliko Gradiste, and Kacarevo, respectively. Positive correlation was obtained also between fluoride in tap water and hair samples in all regions under the study, with statistical significance only in Valjevo municipality, p lt 0.05. Dental examination of schoolchildren confirmed dental fluorosis only in the region of Vranjska Banja. Moreover, in endemic fluorotic region of Vranjska Banja, positive and statistically significant correlations were confirmed between fluoride in well water and dental fluorosis level (r = 0.61; p lt 0.01) and additionally between fluoride in hair and dental fluorosis level (0.62; p lt 0.01). The primary findings from this study have shown that fluoride content in hair is highly correlated with fluoride content in drinking water and dental fluorosis level, indicating that hair may be regarded as biomaterial of high informative potential in evaluating prolonged exposure to fluorides and to individuate children at risk of fluorosis regardless of the phase of teeth eruption.
PB  - Elsevier, Amsterdam
T2  - Science of the Total Environment
T1  - Fluoride in drinking water and dental fluorosis
VL  - 408
IS  - 17
SP  - 3507
EP  - 3512
DO  - 10.1016/j.scitotenv.2010.04.029
ER  - 

@article{
author = "Mandinić, Zoran and Curcić, Marijana and Antonijević, Biljana and Carević, Momir and Mandić, Jelena and Đukić-Ćosić, Danijela and Lekić, Charles P.",
year = "2010",
abstract = "In this study we determined the fluoride content in drinking water and hair of 12-year-old schoolchildren from different Serbian municipalities, i.e. Valley, Veliko Gradiste, Kacarevo and Vranjska Banja. The analyses were performed using composite fluoride ion-selective electrode. Average fluoride levels were 0.10, 0.15, 0.79 and 11 ppm in well water, 0.07, 0.10, 0.17 and 0.15 ppm in tap water, 19.3, 21.5, 25.4, and 32.5 ppm in hair samples, in Valjevo, Veliko Gradiste, Kacarevo and Vranjska Banja, respectively. Correlation analysis indicated statistically significant positive relationship between fluoride in wells water and fluoride in hair, for all municipalities: correlation coefficients were 0.54 (p lt 0.05), 0.89, 0.97 and 0.99 (p lt 0.001), in Vranjska Banja, Valjevo, Veliko Gradiste, and Kacarevo, respectively. Positive correlation was obtained also between fluoride in tap water and hair samples in all regions under the study, with statistical significance only in Valjevo municipality, p lt 0.05. Dental examination of schoolchildren confirmed dental fluorosis only in the region of Vranjska Banja. Moreover, in endemic fluorotic region of Vranjska Banja, positive and statistically significant correlations were confirmed between fluoride in well water and dental fluorosis level (r = 0.61; p lt 0.01) and additionally between fluoride in hair and dental fluorosis level (0.62; p lt 0.01). The primary findings from this study have shown that fluoride content in hair is highly correlated with fluoride content in drinking water and dental fluorosis level, indicating that hair may be regarded as biomaterial of high informative potential in evaluating prolonged exposure to fluorides and to individuate children at risk of fluorosis regardless of the phase of teeth eruption.",
publisher = "Elsevier, Amsterdam",
journal = "Science of the Total Environment",
title = "Fluoride in drinking water and dental fluorosis",
volume = "408",
number = "17",
pages = "3507-3512",
doi = "10.1016/j.scitotenv.2010.04.029"
}

Mandinić, Z., Curcić, M., Antonijević, B., Carević, M., Mandić, J., Đukić-Ćosić, D.,& Lekić, C. P.. (2010). Fluoride in drinking water and dental fluorosis. in Science of the Total Environment
Elsevier, Amsterdam., 408(17), 3507-3512.
https://doi.org/10.1016/j.scitotenv.2010.04.029

Mandinić Z, Curcić M, Antonijević B, Carević M, Mandić J, Đukić-Ćosić D, Lekić CP. Fluoride in drinking water and dental fluorosis. in Science of the Total Environment. 2010;408(17):3507-3512.
doi:10.1016/j.scitotenv.2010.04.029 .

Mandinić, Zoran, Curcić, Marijana, Antonijević, Biljana, Carević, Momir, Mandić, Jelena, Đukić-Ćosić, Danijela, Lekić, Charles P., "Fluoride in drinking water and dental fluorosis" in Science of the Total Environment, 408, no. 17 (2010):3507-3512,
https://doi.org/10.1016/j.scitotenv.2010.04.029 . .

TY  - CONF
AU  - Mandinić, Zoran
AU  - Curcić, Marijana
AU  - Antonijević, Biljana
AU  - Carević, Momir
PY  - 2009
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1488
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Relationship between dental fluorosis and fluoride content in hair of schoolchildren from fluorotic and non-fluorotic regions in Serbia
VL  - 189
SP  - S236
EP  - S236
DO  - 10.1016/j.toxlet.2009.06.443
ER  - 

@conference{
author = "Mandinić, Zoran and Curcić, Marijana and Antonijević, Biljana and Carević, Momir",
year = "2009",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Relationship between dental fluorosis and fluoride content in hair of schoolchildren from fluorotic and non-fluorotic regions in Serbia",
volume = "189",
pages = "S236-S236",
doi = "10.1016/j.toxlet.2009.06.443"
}

Mandinić, Z., Curcić, M., Antonijević, B.,& Carević, M.. (2009). Relationship between dental fluorosis and fluoride content in hair of schoolchildren from fluorotic and non-fluorotic regions in Serbia. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 189, S236-S236.
https://doi.org/10.1016/j.toxlet.2009.06.443

Mandinić Z, Curcić M, Antonijević B, Carević M. Relationship between dental fluorosis and fluoride content in hair of schoolchildren from fluorotic and non-fluorotic regions in Serbia. in Toxicology Letters. 2009;189:S236-S236.
doi:10.1016/j.toxlet.2009.06.443 .

Mandinić, Zoran, Curcić, Marijana, Antonijević, Biljana, Carević, Momir, "Relationship between dental fluorosis and fluoride content in hair of schoolchildren from fluorotic and non-fluorotic regions in Serbia" in Toxicology Letters, 189 (2009):S236-S236,
https://doi.org/10.1016/j.toxlet.2009.06.443 . .

TY  - CONF
AU  - Mandinić, Zoran
AU  - Curcić, Marijana
AU  - Antonijević, Biljana
AU  - Nedeljković, Mirjana
AU  - Carević, Momir
PY  - 2007
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1331
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Fluoride levels in hair samples - Biomarker of exposure
VL  - 172
SP  - S119
EP  - S119
DO  - 10.1016/j.toxlet.2007.05.316
ER  - 

@conference{
author = "Mandinić, Zoran and Curcić, Marijana and Antonijević, Biljana and Nedeljković, Mirjana and Carević, Momir",
year = "2007",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Fluoride levels in hair samples - Biomarker of exposure",
volume = "172",
pages = "S119-S119",
doi = "10.1016/j.toxlet.2007.05.316"
}

Mandinić, Z., Curcić, M., Antonijević, B., Nedeljković, M.,& Carević, M.. (2007). Fluoride levels in hair samples - Biomarker of exposure. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 172, S119-S119.
https://doi.org/10.1016/j.toxlet.2007.05.316

Mandinić Z, Curcić M, Antonijević B, Nedeljković M, Carević M. Fluoride levels in hair samples - Biomarker of exposure. in Toxicology Letters. 2007;172:S119-S119.
doi:10.1016/j.toxlet.2007.05.316 .

Mandinić, Zoran, Curcić, Marijana, Antonijević, Biljana, Nedeljković, Mirjana, Carević, Momir, "Fluoride levels in hair samples - Biomarker of exposure" in Toxicology Letters, 172 (2007):S119-S119,
https://doi.org/10.1016/j.toxlet.2007.05.316 . .