TY  - JOUR
AU  - Brković, Božidar
AU  - Prasad, Hari S.
AU  - Rohrer, Michael D.
AU  - Konandreas, George
AU  - Agrogiannis, George
AU  - Antunović, Dragana
AU  - Sandor, George K.B.
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1749
AB  - The aim of this study was to investigate the healing of human extraction sockets filled with beta-tricalcium phosphate and type I collagen (beta-TCP/Clg) cones with or without a barrier membrane. Twenty patients were divided in two groups: (A) beta-TCP/Clg non-membrane and (B) beta-TCP/Clg + barrier membrane. Clinical examination and biopsies from the grafted sites were collected 9 months later. Bone samples were analyzed using histomorphometry and immunohistochemistry. The horizontal dimension of the alveolar ridge was significantly reduced 9 months after socket preservation in the non-membrane group. There was bone formation with no significant differences between the two groups in the areas occupied by new bone (A = 42.4%; B = 45.3%), marrow (A = 42.7%; B = 35.7%), or residual graft (A = 9.7%; B = 12.5%). Immunohistochemistry revealed osteonectin expression in both groups. Both groups demonstrated sufficient amounts of vital bone and socket morphology to support dental implant placement after the 9-month healing period. A future trial to evaluate the alveolar outcomes at an earlier 6-month time point rather than the 9 months used in this study would be of interest.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation
VL  - 16
IS  - 2
SP  - 581
EP  - 590
DO  - 10.1007/s00784-011-0531-1
ER  - 

@article{
author = "Brković, Božidar and Prasad, Hari S. and Rohrer, Michael D. and Konandreas, George and Agrogiannis, George and Antunović, Dragana and Sandor, George K.B.",
year = "2012",
abstract = "The aim of this study was to investigate the healing of human extraction sockets filled with beta-tricalcium phosphate and type I collagen (beta-TCP/Clg) cones with or without a barrier membrane. Twenty patients were divided in two groups: (A) beta-TCP/Clg non-membrane and (B) beta-TCP/Clg + barrier membrane. Clinical examination and biopsies from the grafted sites were collected 9 months later. Bone samples were analyzed using histomorphometry and immunohistochemistry. The horizontal dimension of the alveolar ridge was significantly reduced 9 months after socket preservation in the non-membrane group. There was bone formation with no significant differences between the two groups in the areas occupied by new bone (A = 42.4%; B = 45.3%), marrow (A = 42.7%; B = 35.7%), or residual graft (A = 9.7%; B = 12.5%). Immunohistochemistry revealed osteonectin expression in both groups. Both groups demonstrated sufficient amounts of vital bone and socket morphology to support dental implant placement after the 9-month healing period. A future trial to evaluate the alveolar outcomes at an earlier 6-month time point rather than the 9 months used in this study would be of interest.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation",
volume = "16",
number = "2",
pages = "581-590",
doi = "10.1007/s00784-011-0531-1"
}

Brković, B., Prasad, H. S., Rohrer, M. D., Konandreas, G., Agrogiannis, G., Antunović, D.,& Sandor, G. K.B.. (2012). Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 16(2), 581-590.
https://doi.org/10.1007/s00784-011-0531-1

Brković B, Prasad HS, Rohrer MD, Konandreas G, Agrogiannis G, Antunović D, Sandor GK. Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation. in Clinical Oral Investigations. 2012;16(2):581-590.
doi:10.1007/s00784-011-0531-1 .

Brković, Božidar, Prasad, Hari S., Rohrer, Michael D., Konandreas, George, Agrogiannis, George, Antunović, Dragana, Sandor, George K.B., "Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation" in Clinical Oral Investigations, 16, no. 2 (2012):581-590,
https://doi.org/10.1007/s00784-011-0531-1 . .

TY  - JOUR
AU  - Brković, Božidar
AU  - Prasad, Hari S.
AU  - Konandreas, George
AU  - Radulović, Milan
AU  - Antunović, Dragana
AU  - Sandor, George K.B.
AU  - Rohrer, Michael D.
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1390
AB  - Alveolar atrophy following tooth extraction remains a challenge for future dental implant placement. Immediate implant placement and postextraction alveolar preservation are 2 methods that are used to prevent significant postextraction bone loss. In this article, we report the management of a maxillary tooth extraction socket using an alveolar preservation technique involving placement of a cone of beta-tricalcium phosphate (beta-TCP) combined with type I collagen without the use of barrier membranes or flap surgery. Clinical examination revealed solid new bone formation 9 months after the procedure. At the time of implant placement, histomorphometric analysis of the biopsied bone showed that it contained 62.6% mineralized bone, 21.1% bone marrow and 16.3% residual beta-TCP graft. The healed bone was able to support subsequent dental implant placement and loading.
PB  - Canadian Dental Association
T2  - Journal of the Canadian Dental Association
T1  - Simple preservation of a maxillary extraction socket using beta-tricalcium phosphate with type I collagen: Preliminary clinical and histomorphometric observations
VL  - 74
IS  - 6
SP  - 523
EP  - 528
UR  - https://hdl.handle.net/21.15107/rcub_smile_1390
ER  - 

@article{
author = "Brković, Božidar and Prasad, Hari S. and Konandreas, George and Radulović, Milan and Antunović, Dragana and Sandor, George K.B. and Rohrer, Michael D.",
year = "2008",
abstract = "Alveolar atrophy following tooth extraction remains a challenge for future dental implant placement. Immediate implant placement and postextraction alveolar preservation are 2 methods that are used to prevent significant postextraction bone loss. In this article, we report the management of a maxillary tooth extraction socket using an alveolar preservation technique involving placement of a cone of beta-tricalcium phosphate (beta-TCP) combined with type I collagen without the use of barrier membranes or flap surgery. Clinical examination revealed solid new bone formation 9 months after the procedure. At the time of implant placement, histomorphometric analysis of the biopsied bone showed that it contained 62.6% mineralized bone, 21.1% bone marrow and 16.3% residual beta-TCP graft. The healed bone was able to support subsequent dental implant placement and loading.",
publisher = "Canadian Dental Association",
journal = "Journal of the Canadian Dental Association",
title = "Simple preservation of a maxillary extraction socket using beta-tricalcium phosphate with type I collagen: Preliminary clinical and histomorphometric observations",
volume = "74",
number = "6",
pages = "523-528",
url = "https://hdl.handle.net/21.15107/rcub_smile_1390"
}

Brković, B., Prasad, H. S., Konandreas, G., Radulović, M., Antunović, D., Sandor, G. K.B.,& Rohrer, M. D.. (2008). Simple preservation of a maxillary extraction socket using beta-tricalcium phosphate with type I collagen: Preliminary clinical and histomorphometric observations. in Journal of the Canadian Dental Association
Canadian Dental Association., 74(6), 523-528.
https://hdl.handle.net/21.15107/rcub_smile_1390

Brković B, Prasad HS, Konandreas G, Radulović M, Antunović D, Sandor GK, Rohrer MD. Simple preservation of a maxillary extraction socket using beta-tricalcium phosphate with type I collagen: Preliminary clinical and histomorphometric observations. in Journal of the Canadian Dental Association. 2008;74(6):523-528.
https://hdl.handle.net/21.15107/rcub_smile_1390 .

Brković, Božidar, Prasad, Hari S., Konandreas, George, Radulović, Milan, Antunović, Dragana, Sandor, George K.B., Rohrer, Michael D., "Simple preservation of a maxillary extraction socket using beta-tricalcium phosphate with type I collagen: Preliminary clinical and histomorphometric observations" in Journal of the Canadian Dental Association, 74, no. 6 (2008):523-528,
https://hdl.handle.net/21.15107/rcub_smile_1390 .