Lekić, Charles P.

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  • Lekić, Charles P. (2)
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Fluoride in drinking water and dental fluorosis

Mandinić, Zoran; Curcić, Marijana; Antonijević, Biljana; Carević, Momir; Mandić, Jelena; Đukić-Ćosić, Danijela; Lekić, Charles P.

(Elsevier, Amsterdam, 2010)

TY  - JOUR
AU  - Mandinić, Zoran
AU  - Curcić, Marijana
AU  - Antonijević, Biljana
AU  - Carević, Momir
AU  - Mandić, Jelena
AU  - Đukić-Ćosić, Danijela
AU  - Lekić, Charles P.
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1605
AB  - In this study we determined the fluoride content in drinking water and hair of 12-year-old schoolchildren from different Serbian municipalities, i.e. Valley, Veliko Gradiste, Kacarevo and Vranjska Banja. The analyses were performed using composite fluoride ion-selective electrode. Average fluoride levels were 0.10, 0.15, 0.79 and 11 ppm in well water, 0.07, 0.10, 0.17 and 0.15 ppm in tap water, 19.3, 21.5, 25.4, and 32.5 ppm in hair samples, in Valjevo, Veliko Gradiste, Kacarevo and Vranjska Banja, respectively. Correlation analysis indicated statistically significant positive relationship between fluoride in wells water and fluoride in hair, for all municipalities: correlation coefficients were 0.54 (p lt 0.05), 0.89, 0.97 and 0.99 (p lt 0.001), in Vranjska Banja, Valjevo, Veliko Gradiste, and Kacarevo, respectively. Positive correlation was obtained also between fluoride in tap water and hair samples in all regions under the study, with statistical significance only in Valjevo municipality, p lt 0.05. Dental examination of schoolchildren confirmed dental fluorosis only in the region of Vranjska Banja. Moreover, in endemic fluorotic region of Vranjska Banja, positive and statistically significant correlations were confirmed between fluoride in well water and dental fluorosis level (r = 0.61; p lt 0.01) and additionally between fluoride in hair and dental fluorosis level (0.62; p lt 0.01). The primary findings from this study have shown that fluoride content in hair is highly correlated with fluoride content in drinking water and dental fluorosis level, indicating that hair may be regarded as biomaterial of high informative potential in evaluating prolonged exposure to fluorides and to individuate children at risk of fluorosis regardless of the phase of teeth eruption.
PB  - Elsevier, Amsterdam
T2  - Science of the Total Environment
T1  - Fluoride in drinking water and dental fluorosis
VL  - 408
IS  - 17
SP  - 3507
EP  - 3512
DO  - 10.1016/j.scitotenv.2010.04.029
ER  - 
@article{
author = "Mandinić, Zoran and Curcić, Marijana and Antonijević, Biljana and Carević, Momir and Mandić, Jelena and Đukić-Ćosić, Danijela and Lekić, Charles P.",
year = "2010",
abstract = "In this study we determined the fluoride content in drinking water and hair of 12-year-old schoolchildren from different Serbian municipalities, i.e. Valley, Veliko Gradiste, Kacarevo and Vranjska Banja. The analyses were performed using composite fluoride ion-selective electrode. Average fluoride levels were 0.10, 0.15, 0.79 and 11 ppm in well water, 0.07, 0.10, 0.17 and 0.15 ppm in tap water, 19.3, 21.5, 25.4, and 32.5 ppm in hair samples, in Valjevo, Veliko Gradiste, Kacarevo and Vranjska Banja, respectively. Correlation analysis indicated statistically significant positive relationship between fluoride in wells water and fluoride in hair, for all municipalities: correlation coefficients were 0.54 (p lt 0.05), 0.89, 0.97 and 0.99 (p lt 0.001), in Vranjska Banja, Valjevo, Veliko Gradiste, and Kacarevo, respectively. Positive correlation was obtained also between fluoride in tap water and hair samples in all regions under the study, with statistical significance only in Valjevo municipality, p lt 0.05. Dental examination of schoolchildren confirmed dental fluorosis only in the region of Vranjska Banja. Moreover, in endemic fluorotic region of Vranjska Banja, positive and statistically significant correlations were confirmed between fluoride in well water and dental fluorosis level (r = 0.61; p lt 0.01) and additionally between fluoride in hair and dental fluorosis level (0.62; p lt 0.01). The primary findings from this study have shown that fluoride content in hair is highly correlated with fluoride content in drinking water and dental fluorosis level, indicating that hair may be regarded as biomaterial of high informative potential in evaluating prolonged exposure to fluorides and to individuate children at risk of fluorosis regardless of the phase of teeth eruption.",
publisher = "Elsevier, Amsterdam",
journal = "Science of the Total Environment",
title = "Fluoride in drinking water and dental fluorosis",
volume = "408",
number = "17",
pages = "3507-3512",
doi = "10.1016/j.scitotenv.2010.04.029"
}
Mandinić, Z., Curcić, M., Antonijević, B., Carević, M., Mandić, J., Đukić-Ćosić, D.,& Lekić, C. P.. (2010). Fluoride in drinking water and dental fluorosis. in Science of the Total Environment
Elsevier, Amsterdam., 408(17), 3507-3512.
https://doi.org/10.1016/j.scitotenv.2010.04.029
Mandinić Z, Curcić M, Antonijević B, Carević M, Mandić J, Đukić-Ćosić D, Lekić CP. Fluoride in drinking water and dental fluorosis. in Science of the Total Environment. 2010;408(17):3507-3512.
doi:10.1016/j.scitotenv.2010.04.029 .
Mandinić, Zoran, Curcić, Marijana, Antonijević, Biljana, Carević, Momir, Mandić, Jelena, Đukić-Ćosić, Danijela, Lekić, Charles P., "Fluoride in drinking water and dental fluorosis" in Science of the Total Environment, 408, no. 17 (2010):3507-3512,
https://doi.org/10.1016/j.scitotenv.2010.04.029 . .
1
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Relationship between fluoride intake in Serbian children living in two areas with different natural levels of fluorides and occurrence of dental fluorosis

Mandinić, Zoran; Curdc, Marijana; Antonijević, Biljana; Lekić, Charles P.; Carević, Momir

(Pergamon-Elsevier Science Ltd, Oxford, 2009)

TY  - JOUR
AU  - Mandinić, Zoran
AU  - Curdc, Marijana
AU  - Antonijević, Biljana
AU  - Lekić, Charles P.
AU  - Carević, Momir
PY  - 2009
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1507
AB  - The amount of fluoride present naturally in drinking water is highly variable, being dependent upon the individual geological environment from which the water is obtained. Chronic exposure to exceeding fluoride doses induces set of toxic effects, i.e. fluorosis. The aim of this study was to examine fluoride content in water and in the most frequently used vegetables, potato and bean, grown in two different Serbian regions. Le. control region (Valjevo) and high naturally occurring fluoride region (Vranjska Banja), and moreover, to correlate estimated daily intake with dental fluorosis occurrence as an adverse effect of fluoride exposure of schoolchildren in Serbia. Study confirmed significant difference in fluoride content in water, potato and bean, consumed by 12-year-old children in two investigated municipalities. Results of the study indicated positive and statistically significant correlation between daily intake of fluoride and dental fluorosis level in the fluorotic municipality of Vranjska Banja (r = 0.61: p = 0.000017). Obtained relationship could be evaluated by means of binary logistic regression analysis, whereas probability for fluorosis occurrence could be predicted using the following equation: fluorosis occurence (%) (34.852 x C-water - 12.644 x C-potato - 9.362 x C-bean - 7.673) x 100 (Chi-square (3) = 33.033; p  lt  0.001).
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Food & Chemical Toxicology
T1  - Relationship between fluoride intake in Serbian children living in two areas with different natural levels of fluorides and occurrence of dental fluorosis
VL  - 47
IS  - 6
SP  - 1080
EP  - 1084
DO  - 10.1016/j.fct.2009.01.038
ER  - 
@article{
author = "Mandinić, Zoran and Curdc, Marijana and Antonijević, Biljana and Lekić, Charles P. and Carević, Momir",
year = "2009",
abstract = "The amount of fluoride present naturally in drinking water is highly variable, being dependent upon the individual geological environment from which the water is obtained. Chronic exposure to exceeding fluoride doses induces set of toxic effects, i.e. fluorosis. The aim of this study was to examine fluoride content in water and in the most frequently used vegetables, potato and bean, grown in two different Serbian regions. Le. control region (Valjevo) and high naturally occurring fluoride region (Vranjska Banja), and moreover, to correlate estimated daily intake with dental fluorosis occurrence as an adverse effect of fluoride exposure of schoolchildren in Serbia. Study confirmed significant difference in fluoride content in water, potato and bean, consumed by 12-year-old children in two investigated municipalities. Results of the study indicated positive and statistically significant correlation between daily intake of fluoride and dental fluorosis level in the fluorotic municipality of Vranjska Banja (r = 0.61: p = 0.000017). Obtained relationship could be evaluated by means of binary logistic regression analysis, whereas probability for fluorosis occurrence could be predicted using the following equation: fluorosis occurence (%) (34.852 x C-water - 12.644 x C-potato - 9.362 x C-bean - 7.673) x 100 (Chi-square (3) = 33.033; p  lt  0.001).",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Food & Chemical Toxicology",
title = "Relationship between fluoride intake in Serbian children living in two areas with different natural levels of fluorides and occurrence of dental fluorosis",
volume = "47",
number = "6",
pages = "1080-1084",
doi = "10.1016/j.fct.2009.01.038"
}
Mandinić, Z., Curdc, M., Antonijević, B., Lekić, C. P.,& Carević, M.. (2009). Relationship between fluoride intake in Serbian children living in two areas with different natural levels of fluorides and occurrence of dental fluorosis. in Food & Chemical Toxicology
Pergamon-Elsevier Science Ltd, Oxford., 47(6), 1080-1084.
https://doi.org/10.1016/j.fct.2009.01.038
Mandinić Z, Curdc M, Antonijević B, Lekić CP, Carević M. Relationship between fluoride intake in Serbian children living in two areas with different natural levels of fluorides and occurrence of dental fluorosis. in Food & Chemical Toxicology. 2009;47(6):1080-1084.
doi:10.1016/j.fct.2009.01.038 .
Mandinić, Zoran, Curdc, Marijana, Antonijević, Biljana, Lekić, Charles P., Carević, Momir, "Relationship between fluoride intake in Serbian children living in two areas with different natural levels of fluorides and occurrence of dental fluorosis" in Food & Chemical Toxicology, 47, no. 6 (2009):1080-1084,
https://doi.org/10.1016/j.fct.2009.01.038 . .
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