TY  - JOUR
AU  - Ihde, Stefan
AU  - Kopp, Sigmar
AU  - Gundlach, K.
AU  - Konstantinović, Vitomir
PY  - 2009
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1508
AB  - Objectives. The theories of the effects of radiation therapy on craniofacial and dental implants have been challenged by new models. Animal and clinical studies differ on the importance of dose effect and implant location regarding implant survival. Our purpose was to explore the risks of irradiation regarding dose levels, timing of radiation, implant location, and material. Study design. A systematic search of the literature was performed to identify studies reporting animal and human data on the success of implants in irradiated versus nonirradiated bone. Results. Eleven animal studies exploring histomorphometric, biomechanical, and histologic features of implants in irradiated bone were summarized. Sixteen human clinical studies evaluating craniofacial (n = 8) and dental (n = 8) implants in irradiated bone were summarized. No meta-analyses of dental implants in irradiated bone were found. Efficacy studies comparing different implant types in irradiated bone were not found. Conclusion. Studies from both animal subjects and human patients indicate that irradiated bone has a greater risk of implant failure than nonirradiated bone. This increase in risk may be up to 12 times greater; however, studies making these comparisons are of poor to moderate quality, so the magnitude of this difference should be accepted with caution. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 56-65)
PB  - Mosby-Elsevier, New York
T2  - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
T1  - Effects of radiation therapy on craniofacial and dental implants: a review of the literature
VL  - 107
IS  - 1
SP  - 56
EP  - 65
DO  - 10.1016/j.tripleo.2008.06.014
ER  - 

@article{
author = "Ihde, Stefan and Kopp, Sigmar and Gundlach, K. and Konstantinović, Vitomir",
year = "2009",
abstract = "Objectives. The theories of the effects of radiation therapy on craniofacial and dental implants have been challenged by new models. Animal and clinical studies differ on the importance of dose effect and implant location regarding implant survival. Our purpose was to explore the risks of irradiation regarding dose levels, timing of radiation, implant location, and material. Study design. A systematic search of the literature was performed to identify studies reporting animal and human data on the success of implants in irradiated versus nonirradiated bone. Results. Eleven animal studies exploring histomorphometric, biomechanical, and histologic features of implants in irradiated bone were summarized. Sixteen human clinical studies evaluating craniofacial (n = 8) and dental (n = 8) implants in irradiated bone were summarized. No meta-analyses of dental implants in irradiated bone were found. Efficacy studies comparing different implant types in irradiated bone were not found. Conclusion. Studies from both animal subjects and human patients indicate that irradiated bone has a greater risk of implant failure than nonirradiated bone. This increase in risk may be up to 12 times greater; however, studies making these comparisons are of poor to moderate quality, so the magnitude of this difference should be accepted with caution. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 56-65)",
publisher = "Mosby-Elsevier, New York",
journal = "Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology",
title = "Effects of radiation therapy on craniofacial and dental implants: a review of the literature",
volume = "107",
number = "1",
pages = "56-65",
doi = "10.1016/j.tripleo.2008.06.014"
}

Ihde, S., Kopp, S., Gundlach, K.,& Konstantinović, V.. (2009). Effects of radiation therapy on craniofacial and dental implants: a review of the literature. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
Mosby-Elsevier, New York., 107(1), 56-65.
https://doi.org/10.1016/j.tripleo.2008.06.014

Ihde S, Kopp S, Gundlach K, Konstantinović V. Effects of radiation therapy on craniofacial and dental implants: a review of the literature. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology. 2009;107(1):56-65.
doi:10.1016/j.tripleo.2008.06.014 .

Ihde, Stefan, Kopp, Sigmar, Gundlach, K., Konstantinović, Vitomir, "Effects of radiation therapy on craniofacial and dental implants: a review of the literature" in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology, 107, no. 1 (2009):56-65,
https://doi.org/10.1016/j.tripleo.2008.06.014 . .