TY  - JOUR
AU  - Kanjevac, Tatjana
AU  - Milovanović, Marija
AU  - Milošević-Đorđević, Olivera
AU  - Tešić, Živoslav
AU  - Ivanović, Mirjana
AU  - Lukić, Aleksandra
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1968
AB  - Stem cells from human exfoliated deciduous teeth (SHED) can be used as a cell-based therapy in regenerative medicine and in immunomodulation. Pulp from human deciduous teeth can be stored as a source of SHED. Glass ionomer cements (GICs) are commonly used in restorative dentistry and in cavity lining. GICs have lower biocompatibility and are cytotoxic for dental pulp cells. In this study, seven commonly used GICs were tested for their cytotoxic effects on SHED, for their potential to arrest mitosis in cells and induce chromosome aberrations, and were compared with the effects of composite. Fuji II, Fuji VIII, Fuji IX, Fuji plus and Vitrebond had significantly higher cytotoxic effects on SHED than composite. Only SHEDs that have been treated with Fuji I, Fuji IX, Fuji plus and composite recovered the potential for proliferation, but no chromosome aberrations were found after treatment with GICs. The cytotoxic effects of GICs on SHEDs were in strong correlation with combined concentrations of released fluoride, aluminum and strontium ions. Fuji I exhibited the lowest activity towards SHEDs; it did not interrupt mitosis and did not induce chromosome aberrations, and was accompanied by the lowest levels of released F, Al and Sr ions.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - Cytotoxicity of glass ionomer cement on human exfoliated deciduous teeth stem cells correlates with released fluoride, strontium and aluminum ion concentrations
VL  - 67
IS  - 2
SP  - 619
EP  - 630
DO  - 10.2298/ABS141021022K
ER  - 

@article{
author = "Kanjevac, Tatjana and Milovanović, Marija and Milošević-Đorđević, Olivera and Tešić, Živoslav and Ivanović, Mirjana and Lukić, Aleksandra",
year = "2015",
abstract = "Stem cells from human exfoliated deciduous teeth (SHED) can be used as a cell-based therapy in regenerative medicine and in immunomodulation. Pulp from human deciduous teeth can be stored as a source of SHED. Glass ionomer cements (GICs) are commonly used in restorative dentistry and in cavity lining. GICs have lower biocompatibility and are cytotoxic for dental pulp cells. In this study, seven commonly used GICs were tested for their cytotoxic effects on SHED, for their potential to arrest mitosis in cells and induce chromosome aberrations, and were compared with the effects of composite. Fuji II, Fuji VIII, Fuji IX, Fuji plus and Vitrebond had significantly higher cytotoxic effects on SHED than composite. Only SHEDs that have been treated with Fuji I, Fuji IX, Fuji plus and composite recovered the potential for proliferation, but no chromosome aberrations were found after treatment with GICs. The cytotoxic effects of GICs on SHEDs were in strong correlation with combined concentrations of released fluoride, aluminum and strontium ions. Fuji I exhibited the lowest activity towards SHEDs; it did not interrupt mitosis and did not induce chromosome aberrations, and was accompanied by the lowest levels of released F, Al and Sr ions.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Cytotoxicity of glass ionomer cement on human exfoliated deciduous teeth stem cells correlates with released fluoride, strontium and aluminum ion concentrations",
volume = "67",
number = "2",
pages = "619-630",
doi = "10.2298/ABS141021022K"
}

Kanjevac, T., Milovanović, M., Milošević-Đorđević, O., Tešić, Ž., Ivanović, M.,& Lukić, A.. (2015). Cytotoxicity of glass ionomer cement on human exfoliated deciduous teeth stem cells correlates with released fluoride, strontium and aluminum ion concentrations. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 67(2), 619-630.
https://doi.org/10.2298/ABS141021022K

Kanjevac T, Milovanović M, Milošević-Đorđević O, Tešić Ž, Ivanović M, Lukić A. Cytotoxicity of glass ionomer cement on human exfoliated deciduous teeth stem cells correlates with released fluoride, strontium and aluminum ion concentrations. in Archives of Biological Sciences. 2015;67(2):619-630.
doi:10.2298/ABS141021022K .

Kanjevac, Tatjana, Milovanović, Marija, Milošević-Đorđević, Olivera, Tešić, Živoslav, Ivanović, Mirjana, Lukić, Aleksandra, "Cytotoxicity of glass ionomer cement on human exfoliated deciduous teeth stem cells correlates with released fluoride, strontium and aluminum ion concentrations" in Archives of Biological Sciences, 67, no. 2 (2015):619-630,
https://doi.org/10.2298/ABS141021022K . .

TY  - JOUR
AU  - Lončar, D.
AU  - Janković, Saša
AU  - Milovanović, D.
AU  - Milošević-Đorđević, Olivera
AU  - Stojadinović, M.
AU  - Lončar, S.
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1636
AB  - Congenital anomalies are the cause of 20.0-25.0% of cases of perinatal death, while 3.0% of children are born with malformations of varying size. We examined the predictive values and defined the credibility ratio of the combined test results. Sensitivity of the test is 94.0%, and specificity is 99.0%. The positive likelihood ratio [likelihood ratio test (LR+)] is 94.00; a negative likelihood ratio [likelihood ratio test (LR-)] is 0.06. The pretest probability that pregnant women carry a fetus with chromosomal abnormality is 1:250. Posttest odds after the combined test to discover this abnormality are 0.3760, and probability of the same case is 0.2732 if it happens that the test result is positive. The result of our study confirms the justification of combined test usage in routine clinical practice, since the posttest odds rate in the case of a positive screening increases several times over (almost 90 times); the probability of detecting a chromosomal abnormality was about 70 times.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - Non-invasive screening: The probability of events
VL  - 63
IS  - 3
SP  - 609
EP  - 615
DO  - 10.2298/ABS1103609L
ER  - 

@article{
author = "Lončar, D. and Janković, Saša and Milovanović, D. and Milošević-Đorđević, Olivera and Stojadinović, M. and Lončar, S.",
year = "2011",
abstract = "Congenital anomalies are the cause of 20.0-25.0% of cases of perinatal death, while 3.0% of children are born with malformations of varying size. We examined the predictive values and defined the credibility ratio of the combined test results. Sensitivity of the test is 94.0%, and specificity is 99.0%. The positive likelihood ratio [likelihood ratio test (LR+)] is 94.00; a negative likelihood ratio [likelihood ratio test (LR-)] is 0.06. The pretest probability that pregnant women carry a fetus with chromosomal abnormality is 1:250. Posttest odds after the combined test to discover this abnormality are 0.3760, and probability of the same case is 0.2732 if it happens that the test result is positive. The result of our study confirms the justification of combined test usage in routine clinical practice, since the posttest odds rate in the case of a positive screening increases several times over (almost 90 times); the probability of detecting a chromosomal abnormality was about 70 times.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Non-invasive screening: The probability of events",
volume = "63",
number = "3",
pages = "609-615",
doi = "10.2298/ABS1103609L"
}

Lončar, D., Janković, S., Milovanović, D., Milošević-Đorđević, O., Stojadinović, M.,& Lončar, S.. (2011). Non-invasive screening: The probability of events. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 63(3), 609-615.
https://doi.org/10.2298/ABS1103609L

Lončar D, Janković S, Milovanović D, Milošević-Đorđević O, Stojadinović M, Lončar S. Non-invasive screening: The probability of events. in Archives of Biological Sciences. 2011;63(3):609-615.
doi:10.2298/ABS1103609L .

Lončar, D., Janković, Saša, Milovanović, D., Milošević-Đorđević, Olivera, Stojadinović, M., Lončar, S., "Non-invasive screening: The probability of events" in Archives of Biological Sciences, 63, no. 3 (2011):609-615,
https://doi.org/10.2298/ABS1103609L . .