TY  - JOUR
AU  - Kršljak, Elena
AU  - Gošić, Katarina
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1411
AB  - Introduction: It is known fact from the literature data that acute and chronic stress influence serum cortisol level. As with serum cortisol, the level of cortisol in saliva is also a reliable marker of stress. Material and method: this study was performed on 25 individuals, females, age 40-50 years. The participants were exposed to long term stress, held two jobs of 8 working hours, six days a weak, domestic work was not included. All of them were high educated, and none of them were on other medication therapy Aim: The Aim of this study was to evaluate possible differences in cortisol levels in stimulated and non stimulated saliva and serum and determine their association with long term stress. Results: Obtained results showed that cortisol level in saliva do not depend on saliva flow rate and increases in the afternoon period in individuals exposed to chronic stress. Correlation (r) between salivary cortisol and plasma cortisol is r= 0.91. Non-invasive sampling procedure suggests that saliva may be used for cortisol measurements in situations where blood sampling is difficult to perform.
AB  - Uvod: U literaturi je poznato da akutni i hronični stres menjaju nivo kortizola u krvi. Kao i u plazmi, nivo kortizola u salivi je pouzdan stres marker. Cilj: Cilj ovog rada je bio da se odredi moguća koncentracija razlika kortizola u stimulisanoj i ne stimulisanoj salivi i plazmi kod osoba izloženih hroničnom stresu i utvrdi njihova međusobna zavisnost. Subjekti i metode: U ispitivanje je uključeno 25 ispitanica ženskog pola, starosti 40 godina izloženih hroničnom stresu tokom poslednjih pet godina. Uzimani su uzorci nestimulisane i stimulisane pljuvačke i uzorci plazme u sredini radne nedelje i na polovini radnog vremena, a koncentracija kortizola je određivana ELISA - imunoeseo testom - Eclia. Rezultati: Dobijeni rezultati pokazuju da se nivo kortizola ne menja u odnosu na protok salive i da se povećava tokom popodneva kod osoba izloženih hroničnom stresu. Korelacija (r) između nivoa kortizola u salivi i plazmi iznosi r = 0,91. Ne invazivna procedura omogućava da se saliva može koristiti za određivanje nivoa kortizola u situacijama kada je otežano uzimanje uzorka krvi.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Determination of cortisol levels in plasma and saliva in women exposed to chronic stress
T1  - Utvrđivanje vrednosti kortizola u serumu i salivi kod žena izloženih hroničnom stresu
VL  - 55
IS  - 3
SP  - 163
EP  - 169
DO  - 10.2298/SGS0803163K
ER  - 

@article{
author = "Kršljak, Elena and Gošić, Katarina",
year = "2008",
abstract = "Introduction: It is known fact from the literature data that acute and chronic stress influence serum cortisol level. As with serum cortisol, the level of cortisol in saliva is also a reliable marker of stress. Material and method: this study was performed on 25 individuals, females, age 40-50 years. The participants were exposed to long term stress, held two jobs of 8 working hours, six days a weak, domestic work was not included. All of them were high educated, and none of them were on other medication therapy Aim: The Aim of this study was to evaluate possible differences in cortisol levels in stimulated and non stimulated saliva and serum and determine their association with long term stress. Results: Obtained results showed that cortisol level in saliva do not depend on saliva flow rate and increases in the afternoon period in individuals exposed to chronic stress. Correlation (r) between salivary cortisol and plasma cortisol is r= 0.91. Non-invasive sampling procedure suggests that saliva may be used for cortisol measurements in situations where blood sampling is difficult to perform., Uvod: U literaturi je poznato da akutni i hronični stres menjaju nivo kortizola u krvi. Kao i u plazmi, nivo kortizola u salivi je pouzdan stres marker. Cilj: Cilj ovog rada je bio da se odredi moguća koncentracija razlika kortizola u stimulisanoj i ne stimulisanoj salivi i plazmi kod osoba izloženih hroničnom stresu i utvrdi njihova međusobna zavisnost. Subjekti i metode: U ispitivanje je uključeno 25 ispitanica ženskog pola, starosti 40 godina izloženih hroničnom stresu tokom poslednjih pet godina. Uzimani su uzorci nestimulisane i stimulisane pljuvačke i uzorci plazme u sredini radne nedelje i na polovini radnog vremena, a koncentracija kortizola je određivana ELISA - imunoeseo testom - Eclia. Rezultati: Dobijeni rezultati pokazuju da se nivo kortizola ne menja u odnosu na protok salive i da se povećava tokom popodneva kod osoba izloženih hroničnom stresu. Korelacija (r) između nivoa kortizola u salivi i plazmi iznosi r = 0,91. Ne invazivna procedura omogućava da se saliva može koristiti za određivanje nivoa kortizola u situacijama kada je otežano uzimanje uzorka krvi.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Determination of cortisol levels in plasma and saliva in women exposed to chronic stress, Utvrđivanje vrednosti kortizola u serumu i salivi kod žena izloženih hroničnom stresu",
volume = "55",
number = "3",
pages = "163-169",
doi = "10.2298/SGS0803163K"
}

Kršljak, E.,& Gošić, K.. (2008). Determination of cortisol levels in plasma and saliva in women exposed to chronic stress. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 55(3), 163-169.
https://doi.org/10.2298/SGS0803163K

Kršljak E, Gošić K. Determination of cortisol levels in plasma and saliva in women exposed to chronic stress. in Stomatološki glasnik Srbije. 2008;55(3):163-169.
doi:10.2298/SGS0803163K .

Kršljak, Elena, Gošić, Katarina, "Determination of cortisol levels in plasma and saliva in women exposed to chronic stress" in Stomatološki glasnik Srbije, 55, no. 3 (2008):163-169,
https://doi.org/10.2298/SGS0803163K . .