Synthesis, processing and characterization of nanostructured materials for application in the field of energy, mechanical engineering, environmental protection and biomedicine

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Synthesis, processing and characterization of nanostructured materials for application in the field of energy, mechanical engineering, environmental protection and biomedicine (en)
Синтеза, процесирање и карактеризација наноструктурних материјала за примену у области енергије, механичког инжењерства, заштите животне стредине и биомедицине (sr)
Sinteza, procesiranje i karakterizacija nanostrukturnih materijala za primenu u oblasti energije, mehaničkog inženjerstva, zaštite životne stredine i biomedicine (sr_RS)
Authors

Publications

Recasting as a booster of Ag-Pd alloy cytotoxicity: induction of cell senescence prior to mass cell death

Čairović, Aleksandra; Stanimirović, Dragan; Krajnović, Tamara T.; Dojčinović, Biljana; Maksimović, Vesna; Cvijović-Alagić, Ivana

(Srpsko biološko društvo, Beograd, i dr., 2019)

TY  - JOUR
AU  - Čairović, Aleksandra
AU  - Stanimirović, Dragan
AU  - Krajnović, Tamara T.
AU  - Dojčinović, Biljana
AU  - Maksimović, Vesna
AU  - Cvijović-Alagić, Ivana
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2386
AB  - The biological quality and chemical composition of alloys used in dental practice change during heat treatment. Often the residues of the previous cast are not disposed of but are reused and recycled until consumed. Thus, manufactured dental restorations have modified biological quality and chemical composition, and compromised biocompatibility. The aim of this study was to investigate the influence of repeated casting on the cytotoxicity of the silver-palladium (Ag-Pd) alloy. Our results showed that repeated casting of the Ag-Pd dental alloy affected its biocompatibility by promoting toxicity against transformed fibroblasts in a contact-independent manner. A strong decrease in cell proliferation, induction of senescence and massive cell death were observed in cultures exposed only to a medium previously incubated with dental alloy samples. The obtained data indicated that toxicity mediated by the accumulation of the Ag, Pd, Cu and Zn cations released from the Ag-Pd material was enhanced by recasting. The induction of cell senescence and subsequent apoptotic and necrotic death were accompanied by amplified intracellular production of reactive oxygen and nitrogen species, suggesting their involvement in the cell destruction process. Therefore, compromised biocompatibility after recasting with the Ag-Pd alloy can be the cause of serious local cell destruction, as observed in clinical practice.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - Recasting as a booster of Ag-Pd alloy cytotoxicity: induction of cell senescence prior to mass cell death
VL  - 71
IS  - 2
SP  - 347
EP  - 356
DO  - 10.2298/ABS190305017C
ER  - 
@article{
author = "Čairović, Aleksandra and Stanimirović, Dragan and Krajnović, Tamara T. and Dojčinović, Biljana and Maksimović, Vesna and Cvijović-Alagić, Ivana",
year = "2019",
abstract = "The biological quality and chemical composition of alloys used in dental practice change during heat treatment. Often the residues of the previous cast are not disposed of but are reused and recycled until consumed. Thus, manufactured dental restorations have modified biological quality and chemical composition, and compromised biocompatibility. The aim of this study was to investigate the influence of repeated casting on the cytotoxicity of the silver-palladium (Ag-Pd) alloy. Our results showed that repeated casting of the Ag-Pd dental alloy affected its biocompatibility by promoting toxicity against transformed fibroblasts in a contact-independent manner. A strong decrease in cell proliferation, induction of senescence and massive cell death were observed in cultures exposed only to a medium previously incubated with dental alloy samples. The obtained data indicated that toxicity mediated by the accumulation of the Ag, Pd, Cu and Zn cations released from the Ag-Pd material was enhanced by recasting. The induction of cell senescence and subsequent apoptotic and necrotic death were accompanied by amplified intracellular production of reactive oxygen and nitrogen species, suggesting their involvement in the cell destruction process. Therefore, compromised biocompatibility after recasting with the Ag-Pd alloy can be the cause of serious local cell destruction, as observed in clinical practice.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Recasting as a booster of Ag-Pd alloy cytotoxicity: induction of cell senescence prior to mass cell death",
volume = "71",
number = "2",
pages = "347-356",
doi = "10.2298/ABS190305017C"
}
Čairović, A., Stanimirović, D., Krajnović, T. T., Dojčinović, B., Maksimović, V.,& Cvijović-Alagić, I.. (2019). Recasting as a booster of Ag-Pd alloy cytotoxicity: induction of cell senescence prior to mass cell death. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 71(2), 347-356.
https://doi.org/10.2298/ABS190305017C
Čairović A, Stanimirović D, Krajnović TT, Dojčinović B, Maksimović V, Cvijović-Alagić I. Recasting as a booster of Ag-Pd alloy cytotoxicity: induction of cell senescence prior to mass cell death. in Archives of Biological Sciences. 2019;71(2):347-356.
doi:10.2298/ABS190305017C .
Čairović, Aleksandra, Stanimirović, Dragan, Krajnović, Tamara T., Dojčinović, Biljana, Maksimović, Vesna, Cvijović-Alagić, Ivana, "Recasting as a booster of Ag-Pd alloy cytotoxicity: induction of cell senescence prior to mass cell death" in Archives of Biological Sciences, 71, no. 2 (2019):347-356,
https://doi.org/10.2298/ABS190305017C . .

Some consequences of repeated casting of Co-Cr dental alloy

Maksimović, Vesna; Stoiljković, Milovan M.; Čairović, Aleksandra

(Srpsko hemijsko društvo, Beograd, 2016)

TY  - JOUR
AU  - Maksimović, Vesna
AU  - Stoiljković, Milovan M.
AU  - Čairović, Aleksandra
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2128
AB  - The effect of multiple recasting of commercial Co-Cr base dental alloy (Dentalite-C) on its structural characteristics and ion release rates in artificial saliva has been investigated. The number of recasting was once, four and eight times. The as-cast microstructure became uniformer as the number of recasting was increased whereby macro-and micro-hardness and electrical conductivity of the castings decreased. Metallic ion release in artificial saliva was monitored in vitro over the period of 22 weeks at the temperature of 37 degrees C and pH 2.3. Only Co and Fe were evidenced in artificial saliva and their release rates are measured. The ion release rates increases with time. The ion release rate of Fe was larger than Co. The ion release rates increases substantially by increasing the number of recasting.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Some consequences of repeated casting of Co-Cr dental alloy
VL  - 81
IS  - 11
SP  - 1307
EP  - 1319
DO  - 10.2298/JSC151204080M
ER  - 
@article{
author = "Maksimović, Vesna and Stoiljković, Milovan M. and Čairović, Aleksandra",
year = "2016",
abstract = "The effect of multiple recasting of commercial Co-Cr base dental alloy (Dentalite-C) on its structural characteristics and ion release rates in artificial saliva has been investigated. The number of recasting was once, four and eight times. The as-cast microstructure became uniformer as the number of recasting was increased whereby macro-and micro-hardness and electrical conductivity of the castings decreased. Metallic ion release in artificial saliva was monitored in vitro over the period of 22 weeks at the temperature of 37 degrees C and pH 2.3. Only Co and Fe were evidenced in artificial saliva and their release rates are measured. The ion release rates increases with time. The ion release rate of Fe was larger than Co. The ion release rates increases substantially by increasing the number of recasting.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Some consequences of repeated casting of Co-Cr dental alloy",
volume = "81",
number = "11",
pages = "1307-1319",
doi = "10.2298/JSC151204080M"
}
Maksimović, V., Stoiljković, M. M.,& Čairović, A.. (2016). Some consequences of repeated casting of Co-Cr dental alloy. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 81(11), 1307-1319.
https://doi.org/10.2298/JSC151204080M
Maksimović V, Stoiljković MM, Čairović A. Some consequences of repeated casting of Co-Cr dental alloy. in Journal of the Serbian Chemical Society. 2016;81(11):1307-1319.
doi:10.2298/JSC151204080M .
Maksimović, Vesna, Stoiljković, Milovan M., Čairović, Aleksandra, "Some consequences of repeated casting of Co-Cr dental alloy" in Journal of the Serbian Chemical Society, 81, no. 11 (2016):1307-1319,
https://doi.org/10.2298/JSC151204080M . .
2
2

The recasting effects on the high gold dental alloy properties

Maksimović, Vesna; Čairović, Aleksandra; Pantić, J.R.; Cvijović-Alagić, Ivana

(Univerzitet u Beogradu - Tehnički fakultet u Boru, Beograd, 2015)

TY  - JOUR
AU  - Maksimović, Vesna
AU  - Čairović, Aleksandra
AU  - Pantić, J.R.
AU  - Cvijović-Alagić, Ivana
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2049
AB  - Noble dental alloys are often reused in dental practice by recasting. The aim of this study was to determine if repeated casting of high gold dental alloys has a detrimental effect on alloy microstructure, type of porosity, structure and microhardness. Results showed that recasting procedure had a strong effect on the change of alloy porosity type. It was also found that alloy microhardness increased with the increase of the number of recasting cycles. At the same time the grain growth and changes of the solid solution phases in the microstructure were observed.
PB  - Univerzitet u Beogradu - Tehnički fakultet u Boru, Beograd
T2  - Journal of Mining & Metallurgy B: Metallurgy
T1  - The recasting effects on the high gold dental alloy properties
VL  - 51
IS  - 1
SP  - 55
EP  - 59
DO  - 10.2298/JMMB130716023M
ER  - 
@article{
author = "Maksimović, Vesna and Čairović, Aleksandra and Pantić, J.R. and Cvijović-Alagić, Ivana",
year = "2015",
abstract = "Noble dental alloys are often reused in dental practice by recasting. The aim of this study was to determine if repeated casting of high gold dental alloys has a detrimental effect on alloy microstructure, type of porosity, structure and microhardness. Results showed that recasting procedure had a strong effect on the change of alloy porosity type. It was also found that alloy microhardness increased with the increase of the number of recasting cycles. At the same time the grain growth and changes of the solid solution phases in the microstructure were observed.",
publisher = "Univerzitet u Beogradu - Tehnički fakultet u Boru, Beograd",
journal = "Journal of Mining & Metallurgy B: Metallurgy",
title = "The recasting effects on the high gold dental alloy properties",
volume = "51",
number = "1",
pages = "55-59",
doi = "10.2298/JMMB130716023M"
}
Maksimović, V., Čairović, A., Pantić, J.R.,& Cvijović-Alagić, I.. (2015). The recasting effects on the high gold dental alloy properties. in Journal of Mining & Metallurgy B: Metallurgy
Univerzitet u Beogradu - Tehnički fakultet u Boru, Beograd., 51(1), 55-59.
https://doi.org/10.2298/JMMB130716023M
Maksimović V, Čairović A, Pantić J, Cvijović-Alagić I. The recasting effects on the high gold dental alloy properties. in Journal of Mining & Metallurgy B: Metallurgy. 2015;51(1):55-59.
doi:10.2298/JMMB130716023M .
Maksimović, Vesna, Čairović, Aleksandra, Pantić, J.R., Cvijović-Alagić, Ivana, "The recasting effects on the high gold dental alloy properties" in Journal of Mining & Metallurgy B: Metallurgy, 51, no. 1 (2015):55-59,
https://doi.org/10.2298/JMMB130716023M . .
2
1

Influence of recasting on biological and microstructural properties of dental alloys

Čairović, Aleksandra

(Univerzitet u Beogradu, Stomatološki fakultet, 2014)

TY  - THES
AU  - Čairović, Aleksandra
PY  - 2014
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=2841
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:11046/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=1024225934
UR  - http://nardus.mpn.gov.rs/123456789/5295
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/973
AB  - Microstructure is the basic factor that determines the properties of any material. The aim of this study is to evaluate the effect of recasting of two commercially available dental alloys, Ni-Cr (Wiron 99) and Co-Cr (Dentalit C), on physiology of cells, as well as comparation those two dental alloys, one containing Ni and the other not. In this study the it was presumed that many times recasted dental alloy has changed microstructure, which influences the physical and mechanical properties and biological quality of the alloy. The specimens of both tested alloys were casted after the first, fourth and eight melting, without adding any amount of new alloy. The microstructural characterization by optical microscopy showed typical dendritic structure of Co-Cr and Ni-Cr alloys after different numbers of recasting. It is well known that the dendritic structure shows differences in chemical composition and that the dendrite branches contain less alloying and trace elements than the interdendritic zone. There were noticed some microstructural changes that were much more obvious by Co-Cr dental alloy. SEM analysis has given more explicit informations about the structure of the examined dental alloys. Based on the binary phase diagram, Ni-Cr alloy shows a wide region of solubillity in solid condition Cr in Ni. In a complex system, as it is in Wiron 99, beside the solid solution of Ni rich phase, there are also phases in the interdendritic zones with irregular shapes, depending of the number of recasting. EDS analysis showed the differences in chemical composition of dendritic and the interdendritic zones, that were very small for Wiron 99. For the Co-Cr alloy it was possible to detect the differences in chemical compositions between two zones, dentritic and interdendritic. As the number of recasting was increased, the structure became more homogenous and the difference in the chemical composition was decreased for Co and Mo, while the rest of the traceing elements Cr, Fe and Si were homogenous in the analyzed zones. X-ray analysis of the specimens of the Ni-Cr dental alloy indicate that there were only reflections of face centered cubic crystal lattice of solid solution of α-Ni phase. It was established that the increase of the number of recasting changes the relative intensity of diffraction maximum. Also, there were changes in the preferred orientation of the crystallites with the increase of the number of recasting...
AB  - Mikrostruktura je osnovni faktor koji određuje svojstva nekog materijala. Cilj ove studije je procena mikrostrukturnih promena nakon višestrukog pretapanja dve komercijalne dentalne legure, Ni-Cr (Wiron 99) i Co-Cr (Dentalit C) i njihov uticaj na fiziološke procese ćelija, kao i komparacija kvaliteta dve ispitivane legure, od kojih jedna sadrži, a druga ne sadrži Ni. U ovom istraživanju pošlo se od pretpostavke da više puta topljenja i livenja dentalna legura ima promenjenu mikrostrukturu, koja utiče na izmenu fizičko-mehaničkih svojstava i biološkog kvaliteta legura. Uzorci obe ispitivane legure izliveni su nakon prvog, četvrtog i osmog topljenja, bez dodavanja nove legure. U cilju mikrostrukturne karakterizacije optičkom mikroskopijom uočena je tipična dendritna struktura uzoraka Co-Cr, kao i Ni-Cr dentalne legure, nakon različitog broja topljenja i livenja. Poznato je da dendritna struktura pokazuje razliku u hemijskom sastavu i da dendritne grane sadrže manje legirajućih i pratećih elemenata nego međudendritni prostor. Uočene su promene u mikrostrukturi koje su znatno izražejnije kod Co-Cr dentalne legure. SEM analiza je dala jasnije podatke o strukturi ispitivanih uzoraka dentalnih legura. Poznato je na osnovu binarnog dijagrama stanja da Ni-Cr sistem pokazuje široku oblast rastvorljivosti u čvrstom stanju Cr u Ni. U složenom sistemu kao što je Wiron 99 pored čvrstog rastvora bogatog Ni uočavaju se i faze u međudendritnom prostoru nepravilnog oblika, koje menjaju svoj raspored u zavisnosti od broja ponavljanih topljenja i livenja. EDS analizom utvrđeno je da se razlika u hemijskom sastavu dendrita i međudendritnog prostora veoma mala za leguru Wiron 99. Kada je u pitanju legura na bazi Co-Cr, bilo je moguće praćenje razlike u hemijskom sastavu između dve zone, dendrit-međudendritni prostor. Sa povećanjem broja ponovljenog topljenja i livenja uočeno je da dolazi do homogenizacije strukture, odnosno do smanjenja razlike u hemijskom sastavu i da je to najuočljivije za elemente Co i Mo, dok ostali praćeni elemente Cr, Fe i Si imaju ravnomernu (homegenu) raspodelu u analiziranim zonama. Rendgenostrukturnom analizom uzoraka Ni-Cr dentalne legure uočene su samo refleksije površinski centrirane kubne kristalne rešetke čvrstog rastvora α-Ni. Utvrđeno je da sa povećanjem broja topljenja i livenja legure, menjaju relativni intenziteti difrakcionih maksimuma. Takođe se menja i preferentna orjentacija kristalita sa povećanjem broja ponovljenog topljenja i livenja...
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Influence of recasting on biological and microstructural properties of dental alloys
T1  - Uticaj termičke obrade na biološka i mikrostrukturna svojstva dentalnih legura
UR  - https://hdl.handle.net/21.15107/rcub_nardus_5295
ER  - 
@phdthesis{
author = "Čairović, Aleksandra",
year = "2014",
abstract = "Microstructure is the basic factor that determines the properties of any material. The aim of this study is to evaluate the effect of recasting of two commercially available dental alloys, Ni-Cr (Wiron 99) and Co-Cr (Dentalit C), on physiology of cells, as well as comparation those two dental alloys, one containing Ni and the other not. In this study the it was presumed that many times recasted dental alloy has changed microstructure, which influences the physical and mechanical properties and biological quality of the alloy. The specimens of both tested alloys were casted after the first, fourth and eight melting, without adding any amount of new alloy. The microstructural characterization by optical microscopy showed typical dendritic structure of Co-Cr and Ni-Cr alloys after different numbers of recasting. It is well known that the dendritic structure shows differences in chemical composition and that the dendrite branches contain less alloying and trace elements than the interdendritic zone. There were noticed some microstructural changes that were much more obvious by Co-Cr dental alloy. SEM analysis has given more explicit informations about the structure of the examined dental alloys. Based on the binary phase diagram, Ni-Cr alloy shows a wide region of solubillity in solid condition Cr in Ni. In a complex system, as it is in Wiron 99, beside the solid solution of Ni rich phase, there are also phases in the interdendritic zones with irregular shapes, depending of the number of recasting. EDS analysis showed the differences in chemical composition of dendritic and the interdendritic zones, that were very small for Wiron 99. For the Co-Cr alloy it was possible to detect the differences in chemical compositions between two zones, dentritic and interdendritic. As the number of recasting was increased, the structure became more homogenous and the difference in the chemical composition was decreased for Co and Mo, while the rest of the traceing elements Cr, Fe and Si were homogenous in the analyzed zones. X-ray analysis of the specimens of the Ni-Cr dental alloy indicate that there were only reflections of face centered cubic crystal lattice of solid solution of α-Ni phase. It was established that the increase of the number of recasting changes the relative intensity of diffraction maximum. Also, there were changes in the preferred orientation of the crystallites with the increase of the number of recasting..., Mikrostruktura je osnovni faktor koji određuje svojstva nekog materijala. Cilj ove studije je procena mikrostrukturnih promena nakon višestrukog pretapanja dve komercijalne dentalne legure, Ni-Cr (Wiron 99) i Co-Cr (Dentalit C) i njihov uticaj na fiziološke procese ćelija, kao i komparacija kvaliteta dve ispitivane legure, od kojih jedna sadrži, a druga ne sadrži Ni. U ovom istraživanju pošlo se od pretpostavke da više puta topljenja i livenja dentalna legura ima promenjenu mikrostrukturu, koja utiče na izmenu fizičko-mehaničkih svojstava i biološkog kvaliteta legura. Uzorci obe ispitivane legure izliveni su nakon prvog, četvrtog i osmog topljenja, bez dodavanja nove legure. U cilju mikrostrukturne karakterizacije optičkom mikroskopijom uočena je tipična dendritna struktura uzoraka Co-Cr, kao i Ni-Cr dentalne legure, nakon različitog broja topljenja i livenja. Poznato je da dendritna struktura pokazuje razliku u hemijskom sastavu i da dendritne grane sadrže manje legirajućih i pratećih elemenata nego međudendritni prostor. Uočene su promene u mikrostrukturi koje su znatno izražejnije kod Co-Cr dentalne legure. SEM analiza je dala jasnije podatke o strukturi ispitivanih uzoraka dentalnih legura. Poznato je na osnovu binarnog dijagrama stanja da Ni-Cr sistem pokazuje široku oblast rastvorljivosti u čvrstom stanju Cr u Ni. U složenom sistemu kao što je Wiron 99 pored čvrstog rastvora bogatog Ni uočavaju se i faze u međudendritnom prostoru nepravilnog oblika, koje menjaju svoj raspored u zavisnosti od broja ponavljanih topljenja i livenja. EDS analizom utvrđeno je da se razlika u hemijskom sastavu dendrita i međudendritnog prostora veoma mala za leguru Wiron 99. Kada je u pitanju legura na bazi Co-Cr, bilo je moguće praćenje razlike u hemijskom sastavu između dve zone, dendrit-međudendritni prostor. Sa povećanjem broja ponovljenog topljenja i livenja uočeno je da dolazi do homogenizacije strukture, odnosno do smanjenja razlike u hemijskom sastavu i da je to najuočljivije za elemente Co i Mo, dok ostali praćeni elemente Cr, Fe i Si imaju ravnomernu (homegenu) raspodelu u analiziranim zonama. Rendgenostrukturnom analizom uzoraka Ni-Cr dentalne legure uočene su samo refleksije površinski centrirane kubne kristalne rešetke čvrstog rastvora α-Ni. Utvrđeno je da sa povećanjem broja topljenja i livenja legure, menjaju relativni intenziteti difrakcionih maksimuma. Takođe se menja i preferentna orjentacija kristalita sa povećanjem broja ponovljenog topljenja i livenja...",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Influence of recasting on biological and microstructural properties of dental alloys, Uticaj termičke obrade na biološka i mikrostrukturna svojstva dentalnih legura",
url = "https://hdl.handle.net/21.15107/rcub_nardus_5295"
}
Čairović, A.. (2014). Influence of recasting on biological and microstructural properties of dental alloys. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_nardus_5295
Čairović A. Influence of recasting on biological and microstructural properties of dental alloys. 2014;.
https://hdl.handle.net/21.15107/rcub_nardus_5295 .
Čairović, Aleksandra, "Influence of recasting on biological and microstructural properties of dental alloys" (2014),
https://hdl.handle.net/21.15107/rcub_nardus_5295 .

In vitro assessment of ni-cr and co-cr dental alloys upon recasting: cellular compatibility

Čairović, Aleksandra; Đorđević, Ivan; Bulatović, Mirna; Mojić, Marija; Momcilović, Miljana; Stošic-Grujicić, Stanislava; Maksimović, Vesna; Maksimović-Ivanić, Danijela; Mijatović, Sanja; Stamenković, Dragoslav

(2013)

TY  - JOUR
AU  - Čairović, Aleksandra
AU  - Đorđević, Ivan
AU  - Bulatović, Mirna
AU  - Mojić, Marija
AU  - Momcilović, Miljana
AU  - Stošic-Grujicić, Stanislava
AU  - Maksimović, Vesna
AU  - Maksimović-Ivanić, Danijela
AU  - Mijatović, Sanja
AU  - Stamenković, Dragoslav
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1826
AB  - The aim of this study was to evaluate the effect of recasting of commercially available Ni-Cr (Wiron 99) and Co-Cr (Dentalit C) dental alloys on physiology of microenvironmental cells. The viability of fibrosarcoma (L929) cells, human embrional fibroblasts (MRC-5) and isolated peripheral blood mononuclear cells (PBMC) was measured by MTT and acidic phosphatase tests. Presence of dying cells was estimated by Annexin/PI staining while the production of intracellular nitric oxide (NO), reactive oxygen (ROS) and nitrogen (RNS) species was determined by DAF-FM diacetate and DHR staining. Recasting of Ni-Cr alloy intensified its cytotoxicity manifested through enhanced free radicals production, induction of cell death and permamently diminished cell proliferation. On the other hand, after initial toxic effect cells adapted to the presence of Co-Cr alloys. Independently of recasting, Co-Cr alloys are more compatible with microenvironment then Ni-Cr alloy. Oppositely, recasting of Ni-Cr alloy promoted its toxicity.
T2  - Digest Journal of Nanomaterials & Biostructures
T1  - In vitro assessment of ni-cr and co-cr dental alloys upon recasting: cellular compatibility
VL  - 8
IS  - 2
SP  - 877
EP  - 886
UR  - https://hdl.handle.net/21.15107/rcub_vinar_5620
ER  - 
@article{
author = "Čairović, Aleksandra and Đorđević, Ivan and Bulatović, Mirna and Mojić, Marija and Momcilović, Miljana and Stošic-Grujicić, Stanislava and Maksimović, Vesna and Maksimović-Ivanić, Danijela and Mijatović, Sanja and Stamenković, Dragoslav",
year = "2013",
abstract = "The aim of this study was to evaluate the effect of recasting of commercially available Ni-Cr (Wiron 99) and Co-Cr (Dentalit C) dental alloys on physiology of microenvironmental cells. The viability of fibrosarcoma (L929) cells, human embrional fibroblasts (MRC-5) and isolated peripheral blood mononuclear cells (PBMC) was measured by MTT and acidic phosphatase tests. Presence of dying cells was estimated by Annexin/PI staining while the production of intracellular nitric oxide (NO), reactive oxygen (ROS) and nitrogen (RNS) species was determined by DAF-FM diacetate and DHR staining. Recasting of Ni-Cr alloy intensified its cytotoxicity manifested through enhanced free radicals production, induction of cell death and permamently diminished cell proliferation. On the other hand, after initial toxic effect cells adapted to the presence of Co-Cr alloys. Independently of recasting, Co-Cr alloys are more compatible with microenvironment then Ni-Cr alloy. Oppositely, recasting of Ni-Cr alloy promoted its toxicity.",
journal = "Digest Journal of Nanomaterials & Biostructures",
title = "In vitro assessment of ni-cr and co-cr dental alloys upon recasting: cellular compatibility",
volume = "8",
number = "2",
pages = "877-886",
url = "https://hdl.handle.net/21.15107/rcub_vinar_5620"
}
Čairović, A., Đorđević, I., Bulatović, M., Mojić, M., Momcilović, M., Stošic-Grujicić, S., Maksimović, V., Maksimović-Ivanić, D., Mijatović, S.,& Stamenković, D.. (2013). In vitro assessment of ni-cr and co-cr dental alloys upon recasting: cellular compatibility. in Digest Journal of Nanomaterials & Biostructures, 8(2), 877-886.
https://hdl.handle.net/21.15107/rcub_vinar_5620
Čairović A, Đorđević I, Bulatović M, Mojić M, Momcilović M, Stošic-Grujicić S, Maksimović V, Maksimović-Ivanić D, Mijatović S, Stamenković D. In vitro assessment of ni-cr and co-cr dental alloys upon recasting: cellular compatibility. in Digest Journal of Nanomaterials & Biostructures. 2013;8(2):877-886.
https://hdl.handle.net/21.15107/rcub_vinar_5620 .
Čairović, Aleksandra, Đorđević, Ivan, Bulatović, Mirna, Mojić, Marija, Momcilović, Miljana, Stošic-Grujicić, Stanislava, Maksimović, Vesna, Maksimović-Ivanić, Danijela, Mijatović, Sanja, Stamenković, Dragoslav, "In vitro assessment of ni-cr and co-cr dental alloys upon recasting: cellular compatibility" in Digest Journal of Nanomaterials & Biostructures, 8, no. 2 (2013):877-886,
https://hdl.handle.net/21.15107/rcub_vinar_5620 .
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