TY  - JOUR
AU  - Brković, Božidar
AU  - Prasad, Hari S.
AU  - Rohrer, Michael D.
AU  - Konandreas, George
AU  - Agrogiannis, George
AU  - Antunović, Dragana
AU  - Sandor, George K.B.
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1749
AB  - The aim of this study was to investigate the healing of human extraction sockets filled with beta-tricalcium phosphate and type I collagen (beta-TCP/Clg) cones with or without a barrier membrane. Twenty patients were divided in two groups: (A) beta-TCP/Clg non-membrane and (B) beta-TCP/Clg + barrier membrane. Clinical examination and biopsies from the grafted sites were collected 9 months later. Bone samples were analyzed using histomorphometry and immunohistochemistry. The horizontal dimension of the alveolar ridge was significantly reduced 9 months after socket preservation in the non-membrane group. There was bone formation with no significant differences between the two groups in the areas occupied by new bone (A = 42.4%; B = 45.3%), marrow (A = 42.7%; B = 35.7%), or residual graft (A = 9.7%; B = 12.5%). Immunohistochemistry revealed osteonectin expression in both groups. Both groups demonstrated sufficient amounts of vital bone and socket morphology to support dental implant placement after the 9-month healing period. A future trial to evaluate the alveolar outcomes at an earlier 6-month time point rather than the 9 months used in this study would be of interest.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation
VL  - 16
IS  - 2
SP  - 581
EP  - 590
DO  - 10.1007/s00784-011-0531-1
ER  - 

@article{
author = "Brković, Božidar and Prasad, Hari S. and Rohrer, Michael D. and Konandreas, George and Agrogiannis, George and Antunović, Dragana and Sandor, George K.B.",
year = "2012",
abstract = "The aim of this study was to investigate the healing of human extraction sockets filled with beta-tricalcium phosphate and type I collagen (beta-TCP/Clg) cones with or without a barrier membrane. Twenty patients were divided in two groups: (A) beta-TCP/Clg non-membrane and (B) beta-TCP/Clg + barrier membrane. Clinical examination and biopsies from the grafted sites were collected 9 months later. Bone samples were analyzed using histomorphometry and immunohistochemistry. The horizontal dimension of the alveolar ridge was significantly reduced 9 months after socket preservation in the non-membrane group. There was bone formation with no significant differences between the two groups in the areas occupied by new bone (A = 42.4%; B = 45.3%), marrow (A = 42.7%; B = 35.7%), or residual graft (A = 9.7%; B = 12.5%). Immunohistochemistry revealed osteonectin expression in both groups. Both groups demonstrated sufficient amounts of vital bone and socket morphology to support dental implant placement after the 9-month healing period. A future trial to evaluate the alveolar outcomes at an earlier 6-month time point rather than the 9 months used in this study would be of interest.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation",
volume = "16",
number = "2",
pages = "581-590",
doi = "10.1007/s00784-011-0531-1"
}

Brković, B., Prasad, H. S., Rohrer, M. D., Konandreas, G., Agrogiannis, G., Antunović, D.,& Sandor, G. K.B.. (2012). Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 16(2), 581-590.
https://doi.org/10.1007/s00784-011-0531-1

Brković B, Prasad HS, Rohrer MD, Konandreas G, Agrogiannis G, Antunović D, Sandor GK. Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation. in Clinical Oral Investigations. 2012;16(2):581-590.
doi:10.1007/s00784-011-0531-1 .

Brković, Božidar, Prasad, Hari S., Rohrer, Michael D., Konandreas, George, Agrogiannis, George, Antunović, Dragana, Sandor, George K.B., "Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation" in Clinical Oral Investigations, 16, no. 2 (2012):581-590,
https://doi.org/10.1007/s00784-011-0531-1 . .