TY  - JOUR
AU  - Janović, Aleksa
AU  - Milovanović, Petar
AU  - Hahn, Michael
AU  - Rakočević, Zoran
AU  - Amling, Michael
AU  - Busse, Bjoern
AU  - Dimitrijević, Milovan
AU  - Đurić, Marija
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2183
AB  - Background/AimLe Fort lines have traditionally been considered as zones of weakness in the mid-facial skeleton although the structural basis of increased bone fragility at these sites has not yet been investigated. Considering recent findings of occlusal loading-related regional heterogeneity in the mid-facial bone micro-architecture, the aim of this study was to explore whether such heterogeneity in cortical and cancellous bone micro-architecture may contribute to increased fragility at Le Fort fracture sites. Materials and MethodsTwenty-five cortical and thirteen cancellous bone specimens were harvested from a dry skull and analyzed by micro-CT. Specimens were classified into Le Fort or Non-Le Fort groups based on their location in the mid-facial skeleton. ResultsCortical bone along Le Fort lines showed tendencies toward lower thickness (1.50.63 vs 1.75 +/- 0.79; P=.39) and greater porosity (11.48 +/- 5.67 vs 10.28 +/- 5.28; P=.59). A significant difference was detected in the trabecular degree of anisotropy which was higher in cancellous bone from Le Fort fracture sites (2.14 +/- 0.69 vs 1.58 +/- 0.34; P=.02). ConclusionsRegional heterogeneity in cortical bone micro-architecture could not fully explain increased fragility of the mid-facial skeleton at the Le Fort lines. However, regional differences in trabecular bone anisotropy may contribute to increased bone fragility.
PB  - Wiley, Hoboken
T2  - Dental Traumatology
T1  - Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines
VL  - 33
IS  - 4
SP  - 300
EP  - 306
DO  - 10.1111/edt.12333
ER  - 

@article{
author = "Janović, Aleksa and Milovanović, Petar and Hahn, Michael and Rakočević, Zoran and Amling, Michael and Busse, Bjoern and Dimitrijević, Milovan and Đurić, Marija",
year = "2017",
abstract = "Background/AimLe Fort lines have traditionally been considered as zones of weakness in the mid-facial skeleton although the structural basis of increased bone fragility at these sites has not yet been investigated. Considering recent findings of occlusal loading-related regional heterogeneity in the mid-facial bone micro-architecture, the aim of this study was to explore whether such heterogeneity in cortical and cancellous bone micro-architecture may contribute to increased fragility at Le Fort fracture sites. Materials and MethodsTwenty-five cortical and thirteen cancellous bone specimens were harvested from a dry skull and analyzed by micro-CT. Specimens were classified into Le Fort or Non-Le Fort groups based on their location in the mid-facial skeleton. ResultsCortical bone along Le Fort lines showed tendencies toward lower thickness (1.50.63 vs 1.75 +/- 0.79; P=.39) and greater porosity (11.48 +/- 5.67 vs 10.28 +/- 5.28; P=.59). A significant difference was detected in the trabecular degree of anisotropy which was higher in cancellous bone from Le Fort fracture sites (2.14 +/- 0.69 vs 1.58 +/- 0.34; P=.02). ConclusionsRegional heterogeneity in cortical bone micro-architecture could not fully explain increased fragility of the mid-facial skeleton at the Le Fort lines. However, regional differences in trabecular bone anisotropy may contribute to increased bone fragility.",
publisher = "Wiley, Hoboken",
journal = "Dental Traumatology",
title = "Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines",
volume = "33",
number = "4",
pages = "300-306",
doi = "10.1111/edt.12333"
}

Janović, A., Milovanović, P., Hahn, M., Rakočević, Z., Amling, M., Busse, B., Dimitrijević, M.,& Đurić, M.. (2017). Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines. in Dental Traumatology
Wiley, Hoboken., 33(4), 300-306.
https://doi.org/10.1111/edt.12333

Janović A, Milovanović P, Hahn M, Rakočević Z, Amling M, Busse B, Dimitrijević M, Đurić M. Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines. in Dental Traumatology. 2017;33(4):300-306.
doi:10.1111/edt.12333 .

Janović, Aleksa, Milovanović, Petar, Hahn, Michael, Rakočević, Zoran, Amling, Michael, Busse, Bjoern, Dimitrijević, Milovan, Đurić, Marija, "Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines" in Dental Traumatology, 33, no. 4 (2017):300-306,
https://doi.org/10.1111/edt.12333 . .

TY  - JOUR
AU  - Antonijević, Đorđe
AU  - Milovanović, Petar
AU  - Brajković, Denis
AU  - Ilić, Dragan
AU  - Hahn, Michael
AU  - Amling, Michael
AU  - Rakocević, Zlatko
AU  - Đurić, Marija
AU  - Busse, Bjoern
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1994
AB  - The objective of this study was to determine the effects of various irrigation solutions on root canal dentine and gutta-percha surface properties. In addition, the effects of disinfectant chemicals on the wettability and surface morphological properties of the filling materials were evaluated. Ethylenediaminetetraacetic acid (EDTA), citric acid, and ozone were employed as irrigation solutions for dentine and gutta-percha treatment. Thereafter, the samples' microstructure, degree of mineralization, and mechanical properties were assessed by means of quantitative backscattered electron imaging (qBEI) and reference point indentation (RN). A contact angle analyzer was used to measure adhesion on the tested materials. Here, EDTA had the most significant affect on both the mechanical properties and the adhesive behavior of dentine. Citric acid did not affect dentine wettability, whereas the indentation properties and the mineralization were reduced. Similar effects were observed when ozone was used. The dentinal tubules were significantly widened in citric acid compared to the ozone group. EDTA causes considerable micromechanical surface alteration of dentine and gutta-percha, but represents the best option in clinical cases where a high adhesiveness of the filling materials is desired.
PB  - Elsevier Science Bv, Amsterdam
T2  - Applied Surface Science
T1  - Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation
VL  - 355
SP  - 369
EP  - 378
DO  - 10.1016/j.apsusc.2015.07.023
ER  - 

@article{
author = "Antonijević, Đorđe and Milovanović, Petar and Brajković, Denis and Ilić, Dragan and Hahn, Michael and Amling, Michael and Rakocević, Zlatko and Đurić, Marija and Busse, Bjoern",
year = "2015",
abstract = "The objective of this study was to determine the effects of various irrigation solutions on root canal dentine and gutta-percha surface properties. In addition, the effects of disinfectant chemicals on the wettability and surface morphological properties of the filling materials were evaluated. Ethylenediaminetetraacetic acid (EDTA), citric acid, and ozone were employed as irrigation solutions for dentine and gutta-percha treatment. Thereafter, the samples' microstructure, degree of mineralization, and mechanical properties were assessed by means of quantitative backscattered electron imaging (qBEI) and reference point indentation (RN). A contact angle analyzer was used to measure adhesion on the tested materials. Here, EDTA had the most significant affect on both the mechanical properties and the adhesive behavior of dentine. Citric acid did not affect dentine wettability, whereas the indentation properties and the mineralization were reduced. Similar effects were observed when ozone was used. The dentinal tubules were significantly widened in citric acid compared to the ozone group. EDTA causes considerable micromechanical surface alteration of dentine and gutta-percha, but represents the best option in clinical cases where a high adhesiveness of the filling materials is desired.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Applied Surface Science",
title = "Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation",
volume = "355",
pages = "369-378",
doi = "10.1016/j.apsusc.2015.07.023"
}

Antonijević, Đ., Milovanović, P., Brajković, D., Ilić, D., Hahn, M., Amling, M., Rakocević, Z., Đurić, M.,& Busse, B.. (2015). Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation. in Applied Surface Science
Elsevier Science Bv, Amsterdam., 355, 369-378.
https://doi.org/10.1016/j.apsusc.2015.07.023

Antonijević Đ, Milovanović P, Brajković D, Ilić D, Hahn M, Amling M, Rakocević Z, Đurić M, Busse B. Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation. in Applied Surface Science. 2015;355:369-378.
doi:10.1016/j.apsusc.2015.07.023 .

Antonijević, Đorđe, Milovanović, Petar, Brajković, Denis, Ilić, Dragan, Hahn, Michael, Amling, Michael, Rakocević, Zlatko, Đurić, Marija, Busse, Bjoern, "Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation" in Applied Surface Science, 355 (2015):369-378,
https://doi.org/10.1016/j.apsusc.2015.07.023 . .

TY  - JOUR
AU  - Janović, Aleksa
AU  - Milovanović, Petar
AU  - Saveljić, Igor
AU  - Nikolić, Dalibor
AU  - Hahn, Michael
AU  - Rakočević, Zoran
AU  - Filipović, Nenad
AU  - Amling, Michael
AU  - Busse, Bjoern
AU  - Đurić, Marija
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1881
AB  - Although the concept of the occlusal load transfer through the facial skeleton along the buttresses has been extensively studied, there has been no study to link microarchitecture of the mid-facial bones to the occlusal load distribution. The aim of this study was to analyze micro-structural properties of the mid-facial bones in relation to occlusal stress. The study was performed by combining the three-dimensional finite element analysis (3D FEA) and micro-computed tomography analysis (micro-CT). Clenching was simulated on the computer model of the adult male human skull which was also used as a source of bone specimens. After the PEA was run, stress was measured at the specific sites in cortical shell and trabecular bone of the model along and between the buttresses. From the corresponding sites on the skull, twenty-five cortical and thirteen cancellous bone specimens were harvested. The specimens were classified into high stress or low stress group based on the stress levels measured via the FEA. Micro-architecture of each specimen was assessed by micro-CT. In the high stress group, cortical bone showed a tendency toward greater thickness and density, lower porosity, and greater pore separation. Stress-related differences in microstructure between the groups were more pronounced in trabecular bone, which showed significantly greater bone volume fraction (BV/TV) and trabecular thickness (Tb.Th) in the high stress group. Our results suggest that the mid-facial bones in the adult dentate male skull exhibit regional variations in cortical and trabecular bone micro-architecture that could be a consequence of different occlusal
PB  - Elsevier Science Inc, New York
T2  - Bone
T1  - Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading
VL  - 68
SP  - 108
EP  - 114
DO  - 10.1016/j.bone.2014.07.032
ER  - 

@article{
author = "Janović, Aleksa and Milovanović, Petar and Saveljić, Igor and Nikolić, Dalibor and Hahn, Michael and Rakočević, Zoran and Filipović, Nenad and Amling, Michael and Busse, Bjoern and Đurić, Marija",
year = "2014",
abstract = "Although the concept of the occlusal load transfer through the facial skeleton along the buttresses has been extensively studied, there has been no study to link microarchitecture of the mid-facial bones to the occlusal load distribution. The aim of this study was to analyze micro-structural properties of the mid-facial bones in relation to occlusal stress. The study was performed by combining the three-dimensional finite element analysis (3D FEA) and micro-computed tomography analysis (micro-CT). Clenching was simulated on the computer model of the adult male human skull which was also used as a source of bone specimens. After the PEA was run, stress was measured at the specific sites in cortical shell and trabecular bone of the model along and between the buttresses. From the corresponding sites on the skull, twenty-five cortical and thirteen cancellous bone specimens were harvested. The specimens were classified into high stress or low stress group based on the stress levels measured via the FEA. Micro-architecture of each specimen was assessed by micro-CT. In the high stress group, cortical bone showed a tendency toward greater thickness and density, lower porosity, and greater pore separation. Stress-related differences in microstructure between the groups were more pronounced in trabecular bone, which showed significantly greater bone volume fraction (BV/TV) and trabecular thickness (Tb.Th) in the high stress group. Our results suggest that the mid-facial bones in the adult dentate male skull exhibit regional variations in cortical and trabecular bone micro-architecture that could be a consequence of different occlusal",
publisher = "Elsevier Science Inc, New York",
journal = "Bone",
title = "Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading",
volume = "68",
pages = "108-114",
doi = "10.1016/j.bone.2014.07.032"
}

Janović, A., Milovanović, P., Saveljić, I., Nikolić, D., Hahn, M., Rakočević, Z., Filipović, N., Amling, M., Busse, B.,& Đurić, M.. (2014). Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading. in Bone
Elsevier Science Inc, New York., 68, 108-114.
https://doi.org/10.1016/j.bone.2014.07.032

Janović A, Milovanović P, Saveljić I, Nikolić D, Hahn M, Rakočević Z, Filipović N, Amling M, Busse B, Đurić M. Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading. in Bone. 2014;68:108-114.
doi:10.1016/j.bone.2014.07.032 .

Janović, Aleksa, Milovanović, Petar, Saveljić, Igor, Nikolić, Dalibor, Hahn, Michael, Rakočević, Zoran, Filipović, Nenad, Amling, Michael, Busse, Bjoern, Đurić, Marija, "Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading" in Bone, 68 (2014):108-114,
https://doi.org/10.1016/j.bone.2014.07.032 . .