Ministry of Science of the Republic of Serbia, grant number 145012

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Ministry of Science of the Republic of Serbia, grant number 145012

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Publications

Porotic Lesions in Immature Skeletons from Stara Torina, Late Medieval Serbia

Marija, Đurić; Petar, Milovanović; Janović, Aleksa; Drašković, Marko; Đukić, Ksenija; Milenković, Petar

(WILEY, 2008)

TY  - JOUR
AU  - Marija, Đurić
AU  - Petar, Milovanović
AU  - Janović, Aleksa
AU  - Drašković, Marko
AU  - Đukić, Ksenija
AU  - Milenković, Petar
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/3302
AB  - Porotic lesions of immature skeletons have been attracting scientific attention for more than a century. These changes have been documented worldwide and are considered to be one of the indicators of health and/or nutritional status of past human populations. These lesions have frequently been referred to as a nutritional stress indicator, a manifestation of iron-deficiency anaemia, and a condition caused by chronic infections. In this study, 327 immature skeletons from the medieval graveyard of Stara Torina (Serbia) were examined for macroscopic signs of four types of porotic lesions: cribra orbitalia, femoral cribra, humeral cribra, and porotic hyperostosis. Femoral cribra was observed in 83.25% of femora, humeral cribra in 58.46% of cases, cribra orbitalia in 46.12% of orbits, while porotic hyperostosis was recorded in only 2.94% of skulls. The majority of skeletons affected by cribra presented symmetrical lesions. Association between all types of cribra was recorded in 33.33% of skeletons. Historical data supported the hypothesis that the investigated population was exposed to frequent infections, especially parasitic ones, which led to the development of porotic bone lesions via several mechanisms: parasite-induced blood loss and diarrhoea (both iron and magnesium malabsorption) or anaemia as a hepcidin-mediated body adaptive response to infection.
PB  - WILEY
T2  - International Journal of Osteoarchaeology
T1  - Porotic Lesions in Immature Skeletons from Stara Torina, Late Medieval Serbia
VL  - 18
IS  - 5
SP  - 458
EP  - 475
DO  - https://doi.org/10.1002/oa.955
ER  - 
@article{
author = "Marija, Đurić and Petar, Milovanović and Janović, Aleksa and Drašković, Marko and Đukić, Ksenija and Milenković, Petar",
year = "2008",
abstract = "Porotic lesions of immature skeletons have been attracting scientific attention for more than a century. These changes have been documented worldwide and are considered to be one of the indicators of health and/or nutritional status of past human populations. These lesions have frequently been referred to as a nutritional stress indicator, a manifestation of iron-deficiency anaemia, and a condition caused by chronic infections. In this study, 327 immature skeletons from the medieval graveyard of Stara Torina (Serbia) were examined for macroscopic signs of four types of porotic lesions: cribra orbitalia, femoral cribra, humeral cribra, and porotic hyperostosis. Femoral cribra was observed in 83.25% of femora, humeral cribra in 58.46% of cases, cribra orbitalia in 46.12% of orbits, while porotic hyperostosis was recorded in only 2.94% of skulls. The majority of skeletons affected by cribra presented symmetrical lesions. Association between all types of cribra was recorded in 33.33% of skeletons. Historical data supported the hypothesis that the investigated population was exposed to frequent infections, especially parasitic ones, which led to the development of porotic bone lesions via several mechanisms: parasite-induced blood loss and diarrhoea (both iron and magnesium malabsorption) or anaemia as a hepcidin-mediated body adaptive response to infection.",
publisher = "WILEY",
journal = "International Journal of Osteoarchaeology",
title = "Porotic Lesions in Immature Skeletons from Stara Torina, Late Medieval Serbia",
volume = "18",
number = "5",
pages = "458-475",
doi = "https://doi.org/10.1002/oa.955"
}
Marija, Đ., Petar, M., Janović, A., Drašković, M., Đukić, K.,& Milenković, P.. (2008). Porotic Lesions in Immature Skeletons from Stara Torina, Late Medieval Serbia. in International Journal of Osteoarchaeology
WILEY., 18(5), 458-475.
https://doi.org/https://doi.org/10.1002/oa.955
Marija Đ, Petar M, Janović A, Drašković M, Đukić K, Milenković P. Porotic Lesions in Immature Skeletons from Stara Torina, Late Medieval Serbia. in International Journal of Osteoarchaeology. 2008;18(5):458-475.
doi:https://doi.org/10.1002/oa.955 .
Marija, Đurić, Petar, Milovanović, Janović, Aleksa, Drašković, Marko, Đukić, Ksenija, Milenković, Petar, "Porotic Lesions in Immature Skeletons from Stara Torina, Late Medieval Serbia" in International Journal of Osteoarchaeology, 18, no. 5 (2008):458-475,
https://doi.org/https://doi.org/10.1002/oa.955 . .
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