TY  - JOUR
AU  - Jung, Ronald
AU  - Koković, Vladimir
AU  - Jurišić, Milan
AU  - Yaman, Duygu
AU  - Subramani, Karthikeyan
AU  - Weber, Franz E.
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1610
AB  - Objectives: The aim of the present study was to compare a newly developed biodegradable polylactide/polyglycolide/N-methyl-2-pyrrolidone (PLGA/NMP) membrane with a standard resorbable collagen membrane (RCM) in combination with and without the use of a bone substitute material (deproteinized bovine bone mineral [DBBM]) looking at the proposed tenting effect and bone regeneration. Materials and methods: In five adult German sheepdogs, the mandibular premolars P2, P3, P4, and the molar M1 were bilaterally extracted creating two bony defects on each site. A total of 20 dental implants were inserted and allocated to four different treatment modalities within each dog: PLGA/NMP membrane only (Test 1), PLGA/NMP membrane with DBBM (Test 2), RCM only (negative control), and RCM with DBBM (positive control). A histomorphometric analysis was performed 12 weeks after implantation. For statistical analysis, a Friedman test and subsequently a Wilcoxon signed ranks test were applied. Results: In four out of five PLGA/NMP membrane-treated defects, the membranes had broken into pieces without the support of DBBM. This led to a worse outcome than in the RCM group. In combination with DBBM, both membranes revealed similar amounts of area of bone regeneration and bone-to-implant contact without significant differences. On the level of the third implant thread, the PLGA/NMP membrane induced more horizontal bone formation beyond the graft than the RCM. Conclusion: The newly developed PLGA/NMP membrane performs equally well as the RCM when applied in combination with DBBM. Without bone substitute material, the PLGA/NMP membrane performed worse than the RCM in challenging defects, and therefore, a combination with a bone substitute material is recommended.
PB  - Wiley, Hoboken
T2  - Clinical Oral Implants Research
T1  - Guided bone regeneration with a synthetic biodegradable membrane: a comparative study in dogs
VL  - 22
IS  - 8
SP  - 802
EP  - 807
DO  - 10.1111/j.1600-0501.2010.02068.x
ER  - 

@article{
author = "Jung, Ronald and Koković, Vladimir and Jurišić, Milan and Yaman, Duygu and Subramani, Karthikeyan and Weber, Franz E.",
year = "2011",
abstract = "Objectives: The aim of the present study was to compare a newly developed biodegradable polylactide/polyglycolide/N-methyl-2-pyrrolidone (PLGA/NMP) membrane with a standard resorbable collagen membrane (RCM) in combination with and without the use of a bone substitute material (deproteinized bovine bone mineral [DBBM]) looking at the proposed tenting effect and bone regeneration. Materials and methods: In five adult German sheepdogs, the mandibular premolars P2, P3, P4, and the molar M1 were bilaterally extracted creating two bony defects on each site. A total of 20 dental implants were inserted and allocated to four different treatment modalities within each dog: PLGA/NMP membrane only (Test 1), PLGA/NMP membrane with DBBM (Test 2), RCM only (negative control), and RCM with DBBM (positive control). A histomorphometric analysis was performed 12 weeks after implantation. For statistical analysis, a Friedman test and subsequently a Wilcoxon signed ranks test were applied. Results: In four out of five PLGA/NMP membrane-treated defects, the membranes had broken into pieces without the support of DBBM. This led to a worse outcome than in the RCM group. In combination with DBBM, both membranes revealed similar amounts of area of bone regeneration and bone-to-implant contact without significant differences. On the level of the third implant thread, the PLGA/NMP membrane induced more horizontal bone formation beyond the graft than the RCM. Conclusion: The newly developed PLGA/NMP membrane performs equally well as the RCM when applied in combination with DBBM. Without bone substitute material, the PLGA/NMP membrane performed worse than the RCM in challenging defects, and therefore, a combination with a bone substitute material is recommended.",
publisher = "Wiley, Hoboken",
journal = "Clinical Oral Implants Research",
title = "Guided bone regeneration with a synthetic biodegradable membrane: a comparative study in dogs",
volume = "22",
number = "8",
pages = "802-807",
doi = "10.1111/j.1600-0501.2010.02068.x"
}

Jung, R., Koković, V., Jurišić, M., Yaman, D., Subramani, K.,& Weber, F. E.. (2011). Guided bone regeneration with a synthetic biodegradable membrane: a comparative study in dogs. in Clinical Oral Implants Research
Wiley, Hoboken., 22(8), 802-807.
https://doi.org/10.1111/j.1600-0501.2010.02068.x

Jung R, Koković V, Jurišić M, Yaman D, Subramani K, Weber FE. Guided bone regeneration with a synthetic biodegradable membrane: a comparative study in dogs. in Clinical Oral Implants Research. 2011;22(8):802-807.
doi:10.1111/j.1600-0501.2010.02068.x .

Jung, Ronald, Koković, Vladimir, Jurišić, Milan, Yaman, Duygu, Subramani, Karthikeyan, Weber, Franz E., "Guided bone regeneration with a synthetic biodegradable membrane: a comparative study in dogs" in Clinical Oral Implants Research, 22, no. 8 (2011):802-807,
https://doi.org/10.1111/j.1600-0501.2010.02068.x . .

TY  - JOUR
AU  - Rudolf, Rebeka
AU  - Anžel, Ivan
AU  - Gusel, L.
AU  - Stamenković, D.
AU  - Todorović, A.
AU  - Čolić, Miodrag
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1579
AB  - Microstructures of two high noble experimental Au-Pt alloys were compared before and after conditioning for biocompatibility, in order to identify phases and microelements responsible for the alloys' corrosive behaviour. Microstructural characterization was carried-out by optical and scanning electron microscopy, in addition to energy dispersive X-ray analysis. X-ray diffraction was applied to determine the phases' composition and their contribution in the alloys. Additionally, simultaneous thermal analysis was used to identify the temperatures of phase transformations. An overall assessment before conditioning showed that Au-Pt I is a two-phase alloy containing a dominant Au-rich alpha(1) phase and a minor Pt-rich alpha(2) phase, while the Au-Pt II alloy contains in addition three minor phases: AuZn3, Pt3Zn and Au1.4Zn0.52. The highest content of Zn (up to 6.76 wt.%) was detected in the Pt3Zn phase. After RPMI cell culture medium conditioning, the Pt3Zn and AuZn3 phases disappeared, suggesting that they are predominantly responsible for Zn loss and the lower corrosive stability of the Au-Pt II alloy.
PB  - Korean Inst Metals Materials, Seoul
T2  - Metals & Materials International
T1  - Microstructural analyses of two high noble gold-platinum alloys before and after conditioning in a cell culture medium
VL  - 16
IS  - 6
SP  - 931
EP  - 940
DO  - 10.1007/s12540-010-1211-4
ER  - 

@article{
author = "Rudolf, Rebeka and Anžel, Ivan and Gusel, L. and Stamenković, D. and Todorović, A. and Čolić, Miodrag",
year = "2010",
abstract = "Microstructures of two high noble experimental Au-Pt alloys were compared before and after conditioning for biocompatibility, in order to identify phases and microelements responsible for the alloys' corrosive behaviour. Microstructural characterization was carried-out by optical and scanning electron microscopy, in addition to energy dispersive X-ray analysis. X-ray diffraction was applied to determine the phases' composition and their contribution in the alloys. Additionally, simultaneous thermal analysis was used to identify the temperatures of phase transformations. An overall assessment before conditioning showed that Au-Pt I is a two-phase alloy containing a dominant Au-rich alpha(1) phase and a minor Pt-rich alpha(2) phase, while the Au-Pt II alloy contains in addition three minor phases: AuZn3, Pt3Zn and Au1.4Zn0.52. The highest content of Zn (up to 6.76 wt.%) was detected in the Pt3Zn phase. After RPMI cell culture medium conditioning, the Pt3Zn and AuZn3 phases disappeared, suggesting that they are predominantly responsible for Zn loss and the lower corrosive stability of the Au-Pt II alloy.",
publisher = "Korean Inst Metals Materials, Seoul",
journal = "Metals & Materials International",
title = "Microstructural analyses of two high noble gold-platinum alloys before and after conditioning in a cell culture medium",
volume = "16",
number = "6",
pages = "931-940",
doi = "10.1007/s12540-010-1211-4"
}

Rudolf, R., Anžel, I., Gusel, L., Stamenković, D., Todorović, A.,& Čolić, M.. (2010). Microstructural analyses of two high noble gold-platinum alloys before and after conditioning in a cell culture medium. in Metals & Materials International
Korean Inst Metals Materials, Seoul., 16(6), 931-940.
https://doi.org/10.1007/s12540-010-1211-4

Rudolf R, Anžel I, Gusel L, Stamenković D, Todorović A, Čolić M. Microstructural analyses of two high noble gold-platinum alloys before and after conditioning in a cell culture medium. in Metals & Materials International. 2010;16(6):931-940.
doi:10.1007/s12540-010-1211-4 .

Rudolf, Rebeka, Anžel, Ivan, Gusel, L., Stamenković, D., Todorović, A., Čolić, Miodrag, "Microstructural analyses of two high noble gold-platinum alloys before and after conditioning in a cell culture medium" in Metals & Materials International, 16, no. 6 (2010):931-940,
https://doi.org/10.1007/s12540-010-1211-4 . .