TY  - JOUR
AU  - Jovanović, Lena
AU  - Miljević, Llija
AU  - Petrović, Bojan
AU  - Marković, Dejan
AU  - Kojić, Vesna
AU  - Bajkin, Branislav
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1854
AB  - Dental materials should be biocompatible, in order to prevent any adverse effects on the surrounding tissue caused by direct contact. The ideal root end filling material must have certain characteristics, including biocompatibility, satisfying marginal sealing quality, ability to permit or induce repair of alveolar bone, promote periapical healing and antimicrobial activity. In this study, the cytotoxicity of different materials (amalgam, MTA and Biodentine) was evaluated on a permanent fibroblast cell lines (MRC-5 and L929). The cytotoxicity of all three types of materials was investigated using standard biocompatibility tests: DET, MIT and agar diffusion test. MU test showed that after 24 and 48 hours in both cell cultures, Biodentine had the largest percentage of citotoxicity. The lowest percentage of cytotoxicity showed MTA in both groups. After 72 h in both cell lines, the highest percentage of cytotoxicity had amalgam. The lowest percentage of cytotoxicity showed MTA in both groups. Observing the results of Agar diffusion test, there was no any discoloration detected, neither lysis of cells under the disc. Biocompatibility tests showed high level of cell compatibility of all three tested materials.
PB  - Amer Scientific Publishers, Valencia
T2  - Journal of Biomaterials & Tissue Engineering
T1  - Biocompatibility of Three Root End Filling Materials
VL  - 4
IS  - 3
SP  - 253
EP  - 257
DO  - 10.1166/jbt.2014.1165
ER  - 

@article{
author = "Jovanović, Lena and Miljević, Llija and Petrović, Bojan and Marković, Dejan and Kojić, Vesna and Bajkin, Branislav",
year = "2014",
abstract = "Dental materials should be biocompatible, in order to prevent any adverse effects on the surrounding tissue caused by direct contact. The ideal root end filling material must have certain characteristics, including biocompatibility, satisfying marginal sealing quality, ability to permit or induce repair of alveolar bone, promote periapical healing and antimicrobial activity. In this study, the cytotoxicity of different materials (amalgam, MTA and Biodentine) was evaluated on a permanent fibroblast cell lines (MRC-5 and L929). The cytotoxicity of all three types of materials was investigated using standard biocompatibility tests: DET, MIT and agar diffusion test. MU test showed that after 24 and 48 hours in both cell cultures, Biodentine had the largest percentage of citotoxicity. The lowest percentage of cytotoxicity showed MTA in both groups. After 72 h in both cell lines, the highest percentage of cytotoxicity had amalgam. The lowest percentage of cytotoxicity showed MTA in both groups. Observing the results of Agar diffusion test, there was no any discoloration detected, neither lysis of cells under the disc. Biocompatibility tests showed high level of cell compatibility of all three tested materials.",
publisher = "Amer Scientific Publishers, Valencia",
journal = "Journal of Biomaterials & Tissue Engineering",
title = "Biocompatibility of Three Root End Filling Materials",
volume = "4",
number = "3",
pages = "253-257",
doi = "10.1166/jbt.2014.1165"
}

Jovanović, L., Miljević, L., Petrović, B., Marković, D., Kojić, V.,& Bajkin, B.. (2014). Biocompatibility of Three Root End Filling Materials. in Journal of Biomaterials & Tissue Engineering
Amer Scientific Publishers, Valencia., 4(3), 253-257.
https://doi.org/10.1166/jbt.2014.1165

Jovanović L, Miljević L, Petrović B, Marković D, Kojić V, Bajkin B. Biocompatibility of Three Root End Filling Materials. in Journal of Biomaterials & Tissue Engineering. 2014;4(3):253-257.
doi:10.1166/jbt.2014.1165 .

Jovanović, Lena, Miljević, Llija, Petrović, Bojan, Marković, Dejan, Kojić, Vesna, Bajkin, Branislav, "Biocompatibility of Three Root End Filling Materials" in Journal of Biomaterials & Tissue Engineering, 4, no. 3 (2014):253-257,
https://doi.org/10.1166/jbt.2014.1165 . .