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Polymorphisms in methylenetetrahydrofolate reductase, glutathione transferase, tumor necrosis factor alpha and its receptors in oral epithelial tumors. / Ispitivanje polimorfizama gena za metilentetrahidrofolat reduktazu, glutation transferazu, faktor nekroze tumora alfa i njegove receptore u epitelnim tumorima usne duplje
(Univerzitet u Beogradu, Stomatološki fakultet, 2016)
Background: Keratocystic Odontogenic Tumour (KCOT) and Oral Squamous Cell Carcinoma (OSCC) are classified as oral epithelial tumours. Although, the first one has benign and the second one malignant characteristics, they ...
Combined GSTM1 and GSTT1 null genotypes are strong risk factors for atherogenesis in a Serbian population
(Soc Brasil Genetica, Ribeirao Pret, 2018)
Oxidative stress (OS) plays an important role in atherogenesis and since glutathione S-transferases (GSTs) provide protection against OS, we have tested the hypothesis that deletion polymorphisms in two GSTs (GSTM1 and ...
Genetic polymorphisms of paraoxonase 1 and susceptibility to atherogenesis / Genetički polimorfizmi paraoksonaze 1 i podložnost aterogenezi
(Srpsko lekarsko društvo, Beograd, 2013)
Introduction. Paraoxonase 1 (PON1) is a multifunctional enzyme associated with high-density lipoprotein particles (HDL). It is a cellular antioxidant that hydrolyses oxidized macromolecules, especially low-density lipoproteins ...
Endothelial nitric oxide synthase polymorphisms/haplotypes are strong modulators of oral cancer risk in Serbian population
(Nihon University, School of Dentistry, Japan, 2020)
Oral carcinoma is the sixth most common malignancy worldwide, with survival rates of approximately 50%. The major type of oral cancer, present in 90% of the cases, is oral squamous cell carcinoma (OSCC). The genetic ...