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Immunohistochemical study of cyclin A and p16 expression in patients with renal cell carcinoma
(Balkan Union of Oncology (B.U.ON.), 2017)
Purpose: Renal cell carcinoma (RCC) is the most common malignant kidney tumor in adults. Dysregulation of the cell cycle can lead to cancer development. In this study, the mitosis-associated cyclin A and p16, a negative ...
High frequency of p16 and p14 promoter hypermethylation and marked telomere instability in salivary gland tumors
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Objectives: to investigate p16(INK4a) and p14(ARF) tumor suppressor gene methylation status, determine telomere length and assess the importance of these epigenetic and genetic parameters in the development of pleomorphic ...