Приказ основних података о документу
Biocompatibility assessment of glas ionomer cement: Test of cytotoxicity
Ispitivanje biokompatibilnosti glas-jonomer cementa - test citotoksičnosti
dc.creator | Marković, Dejan | |
dc.date.accessioned | 2020-07-02T12:01:48Z | |
dc.date.available | 2020-07-02T12:01:48Z | |
dc.date.issued | 2002 | |
dc.identifier.issn | 0039-1743 | |
dc.identifier.uri | https://smile.stomf.bg.ac.rs/handle/123456789/1147 | |
dc.description.abstract | Evaluation o f cytotoxicity is a first step in assessment of dental materials biocompatibility. Necessity for unique criteria in researches resulted in international standard methodology (ISO). The aim of this study was to assess the cytotoxicity of four restorative materials (three glas ionomer cements and one composite material) and to define adventages and disadventages of common ISO methodology for evaluation of this aspect of dental materials biocompatibility. Research was designed according to ISO/TC 106/1995 and ISO/ 10993-5/1994 methodology. Materials used in this investigation were Fuji IILC (GC), Vitiemer (3M), Ionosit fill (DMG-Hamburg), Luxat (DMG-Hamburg). Evaluation of cytotoxicity was carried out on standardized Human Diploid Cell Lung WI-38. Obtained results showed expressive cytotoxic effect of all investigated materials without statisticaly significant difference. Estimation of material biocompatibility and assessment of obtained results can be made only after establishment of correlation with test results. Common ISO methodology is simple for conductance and reproduction, and use of cell cultures in researches is painless, cost effective and without moral or ethical dilemma. | en |
dc.description.abstract | Ispitivanje cititoksičnosti prvi je korak u ocenjivanu biokompatibilnosti stomatoloških materijala. Potreba za ujednačavanjem kriterijuma za ovakva istraživanja rezultirala je postavljanjem internacionalnih standarda uobličenih u ISO metodologiju. Cilj ovih istraživanja bio je da se ispita cititoksičnost četiri restaurativna materijala (tri glas-jonomer cementa, i jednog kompomera) i da se definišu prednosti i nedostatci aktuelne ISO metodologije za ispitivanje ovog aspekta biokompatibilnosti stomatoloških materijala. Istraživanje je dizajnirano prema ISO/TC 106/1995 i ISO 10993-5 1994. Ispitivanjem su obuhvaćeni Fuji LC II, Vitremer (3M), Ionosit fil (DMG- Hamburg), Luxat (DMG- Hamburg). Ispitivanje citotoksičnosti sprovedene je na standardizovanoj humanoj diploidnoj ćelijskoj liniji WI-38. Rezultati istraživanja pokazali su izražen citotoksičan efekat svih ispitivanih materijala bez statistički značajne razlike. Ocena biokompatibilnosti ovih materijala kao i vrednovanje dobijenih rezultata mogu se doneti tek nakon uspostavljanja korelacije sa rezultatima testova primene. Preporučena ISO metodologija jednostavna je za izvođenje i reprodukovanje, a korišćenje ćelijske kulture u istraživanju je najbezbolnije, najjeftinije i pri tom oslobođeno moralnih i etičkih dilema. | sr |
dc.publisher | Srpsko lekarsko društvo - Stomatološka sekcija, Beograd | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-sa/4.0/ | |
dc.source | Stomatološki glasnik Srbije | |
dc.subject | glas-ionomer cement | en |
dc.subject | biocompatibility | en |
dc.subject | cytotoxicity | en |
dc.subject | glas-jonomer cement | sr |
dc.subject | biokompatibilnost | sr |
dc.subject | čilo toksičnost | sr |
dc.title | Biocompatibility assessment of glas ionomer cement: Test of cytotoxicity | en |
dc.title | Ispitivanje biokompatibilnosti glas-jonomer cementa - test citotoksičnosti | sr |
dc.type | article | |
dc.rights.license | BY-SA | |
dcterms.abstract | Марковић, Дејан; Испитивање биокомпатибилности глас-јономер цемента - тест цитотоксичности; Испитивање биокомпатибилности глас-јономер цемента - тест цитотоксичности; | |
dc.citation.volume | 49 | |
dc.citation.issue | 3-4 | |
dc.citation.spage | 75 | |
dc.citation.epage | 80 | |
dc.citation.other | 49(3-4): 75-80 | |
dc.identifier.doi | 10.2298/SGS0204075M | |
dc.identifier.fulltext | https://smile.stomf.bg.ac.rs/bitstream/id/61/1142.pdf | |
dc.type.version | publishedVersion |