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dc.creatorLeković, Vojislav
dc.creatorCamargo, PM
dc.creatorWeinlaender, Michael
dc.creatorVasilić, N
dc.creatorAleksić, Zoran
dc.creatorKenney, Barrie
dc.date.accessioned2020-07-02T12:04:19Z
dc.date.available2020-07-02T12:04:19Z
dc.date.issued2003
dc.identifier.issn0303-6979
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/1187
dc.description.abstractObjective: A combination of platelet-rich plasma (PRP), bovine porous bone mineral (BPBM) and guided tissue regeneration (GTR) has been shown to be effective as regenerative treatment for intrabony periodontal defects. The purpose of this study was to evaluate the effectiveness of PRP, BPBM and GTR used in combination as regenerative treatment for grade II molar furcation defects in humans. Material and methods: Using a split-mouth design, a total of 52 grade II mandibular molar furcation defects were treated either with PRP/BPBM/GTR (experimental group, n =26) or with an open flap debridement (control group, n =26). The primary outcomes evaluated in this study included changes in pocket depth, attachment level and re-entry bone levels (horizontal and vertical) between baseline and 6 months postoperatively. Results: The results showed that the experimental group presented with significantly greater pocket reduction (4.07+/-0.33 mm for experimental and 2.49+/-0.38 mm for control sites), gain in clinical attachment (3.29 +/- 0.42 mm for experimental and 1.68+/-0.31 mm for control sites), vertical defect fill (2.56+/- 0.36 mm for experimental and -0.19+/-0.02 for control sites) and horizontal defect fill (2.28+/-0.33 mm for experimental and 0.08+/-0.02 mm for control sites) than the control group. Conclusions: It was concluded that the PRP/BPBM/GTR combined technique is an effective modality of regenerative treatment for mandibular grade II furcation defects. Further studies are necessary to elucidate the role played by each component of the combined therapy in achieving these results.en
dc.publisherWiley, Hoboken
dc.rightsrestrictedAccess
dc.sourceJournal of Clinical Periodontology
dc.subjectperiodontalen
dc.subjectregenerationen
dc.subjectfurcationsen
dc.subjectplatelet-rich plasmaen
dc.subjectguided tissue regenerationen
dc.subjectgraften
dc.titleEffectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humansen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЛековић, Војислав; Кеннеy, Баррие; Василић, Н; Wеинлаендер, Мицхаел; Цамарго, ПМ; Aлексић, Зоран;
dc.citation.volume30
dc.citation.issue8
dc.citation.spage746
dc.citation.epage751
dc.citation.other30(8): 746-751
dc.citation.rankM21
dc.identifier.wos000184336300010
dc.identifier.doi10.1034/j.1600-051X.2003.00368.x
dc.identifier.pmid12887344
dc.identifier.scopus2-s2.0-0142093236
dc.type.versionpublishedVersion


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