This experimental study was carried out on 35 Albino Wister rats Artificially created bone defects were grafted with bioactive ceramic materials or control material. Histological analysis was preformed 8 weeks and 6 months after the implantation. The results revealed that bone regeneration occurred in defects treated with bioactive ceramic materials while in the defects treated with the control material signs of tissue rejection were present. As stated before, it could be concluded that bioactive ceramics can be recommended as bone substitutes in orthopedic surgery and dentistry.
Eksperimentalna studija sprovedena je na 35 Albino Wistar pacova kod kojih su, veštački napravljeni defekti u butnoj kosti, popunjavani bioaktivnim keramičkim materijalima i kontrolnim materijalom. Histološka procena zarastanja defekta vršena je 8 nedelja i 6 meseci nakon implantacije. Rezultati histološke analize ukazali su da je u defektima koji su tretirani biokeramičkim materijalima ostvarena koštana regeneracija, dok je u grupi koja je tretirana roze voskom, kao kontrolnim materijalom, bila prisutna reakcija odbacivanja. Na osnovu dobijenih rezultata može se zaključiti da se ispitivani biokeramički materijali mogu koristiti za popunjavanje koštanih defekta u ortopedskoj hirurgiji i stomatologiji.
Ključne reči:
hydroxylapatite (Hap) / Hap-M type 2 / bone regeneration / histology
Izvor:
Acta veterinaria, 2005, 55, 5-6, 461-470
Izdavač:
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
TY - JOUR
AU - Kršljak, Elena
AU - Danilović, Vesna
AU - Teodorović, Nevenka
PY - 2005
UR - https://smile.stomf.bg.ac.rs/handle/123456789/1239
AB - This experimental study was carried out on 35 Albino Wister rats Artificially created bone defects were grafted with bioactive ceramic materials or control material. Histological analysis was preformed 8 weeks and 6 months after the implantation. The results revealed that bone regeneration occurred in defects treated with bioactive ceramic materials while in the defects treated with the control material signs of tissue rejection were present. As stated before, it could be concluded that bioactive ceramics can be recommended as bone substitutes in orthopedic surgery and dentistry.
AB - Eksperimentalna studija sprovedena je na 35 Albino Wistar pacova kod kojih su, veštački napravljeni defekti u butnoj kosti, popunjavani bioaktivnim keramičkim materijalima i kontrolnim materijalom. Histološka procena zarastanja defekta vršena je 8 nedelja i 6 meseci nakon implantacije. Rezultati histološke analize ukazali su da je u defektima koji su tretirani biokeramičkim materijalima ostvarena koštana regeneracija, dok je u grupi koja je tretirana roze voskom, kao kontrolnim materijalom, bila prisutna reakcija odbacivanja. Na osnovu dobijenih rezultata može se zaključiti da se ispitivani biokeramički materijali mogu koristiti za popunjavanje koštanih defekta u ortopedskoj hirurgiji i stomatologiji.
PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2 - Acta veterinaria
T1 - Histological evaluation of bone response to bioactive ceramics as graft material in rats
T1 - Histološka procena odgovora koštanog tkiva na ugradnju bioaktivnih keramičkih materijala kod pacova
VL - 55
IS - 5-6
SP - 461
EP - 470
DO - 10.2298/AVB0506461K
ER -
@article{
author = "Kršljak, Elena and Danilović, Vesna and Teodorović, Nevenka",
year = "2005",
abstract = "This experimental study was carried out on 35 Albino Wister rats Artificially created bone defects were grafted with bioactive ceramic materials or control material. Histological analysis was preformed 8 weeks and 6 months after the implantation. The results revealed that bone regeneration occurred in defects treated with bioactive ceramic materials while in the defects treated with the control material signs of tissue rejection were present. As stated before, it could be concluded that bioactive ceramics can be recommended as bone substitutes in orthopedic surgery and dentistry., Eksperimentalna studija sprovedena je na 35 Albino Wistar pacova kod kojih su, veštački napravljeni defekti u butnoj kosti, popunjavani bioaktivnim keramičkim materijalima i kontrolnim materijalom. Histološka procena zarastanja defekta vršena je 8 nedelja i 6 meseci nakon implantacije. Rezultati histološke analize ukazali su da je u defektima koji su tretirani biokeramičkim materijalima ostvarena koštana regeneracija, dok je u grupi koja je tretirana roze voskom, kao kontrolnim materijalom, bila prisutna reakcija odbacivanja. Na osnovu dobijenih rezultata može se zaključiti da se ispitivani biokeramički materijali mogu koristiti za popunjavanje koštanih defekta u ortopedskoj hirurgiji i stomatologiji.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "Histological evaluation of bone response to bioactive ceramics as graft material in rats, Histološka procena odgovora koštanog tkiva na ugradnju bioaktivnih keramičkih materijala kod pacova",
volume = "55",
number = "5-6",
pages = "461-470",
doi = "10.2298/AVB0506461K"
}
Kršljak, E., Danilović, V.,& Teodorović, N.. (2005). Histological evaluation of bone response to bioactive ceramics as graft material in rats. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 55(5-6), 461-470.
https://doi.org/10.2298/AVB0506461K
Kršljak E, Danilović V, Teodorović N. Histological evaluation of bone response to bioactive ceramics as graft material in rats. in Acta veterinaria. 2005;55(5-6):461-470.
doi:10.2298/AVB0506461K .
Kršljak, Elena, Danilović, Vesna, Teodorović, Nevenka, "Histological evaluation of bone response to bioactive ceramics as graft material in rats" in Acta veterinaria, 55, no. 5-6 (2005):461-470,
https://doi.org/10.2298/AVB0506461K . .
