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dc.creatorBrković, Božidar
dc.creatorTodorović, L
dc.creatorStojić, D.
dc.date.accessioned2020-07-02T12:08:08Z
dc.date.available2020-07-02T12:08:08Z
dc.date.issued2005
dc.identifier.issn0901-5027
dc.identifier.urihttp://smile.stomf.bg.ac.rs/handle/123456789/1246
dc.description.abstractThe admixture of clonidine or epinephrine to lidocaine for inferior alveolar nerve block was studied with regard to onset, duration, intensity of anaesthesia, postoperative analgesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), ST segment depression 1 mm and cardiac arrhythmias. Forty healthy patients (ASA I) received 2 ml 2% lidocaine with clonidine (15 mg/ml; n = 20) or epinephrine (12.5 mg/ml; n = 20) in a doubleblind fashion for lower third molar surgery. Duration and intensity were not different between groups, while onset was significantly different by subjective evaluation. The need for postoperative pain medication was significantly lower in the clonidine group. There was a significant decrease in SBP and MAP in both groups 35 min after administration of anaesthesia compared with basal values, while DBP was significantly lower only in the clonidine group. There was no significant difference in SBP, DBP and MAP between groups. HR was significantly increased in the epinephrine group 5 min after administration of anaesthesia and during surgery compared with the clonidine group and with basal values. The presented data suggest that clonidine could be a useful and safe alternative to epinephrine for intraoral block anaesthesia.en
dc.publisherChurchill Livingstone, Edinburgh
dc.rightsrestrictedAccess
dc.sourceInternational Journal of Oral & Maxillofacial Surgery
dc.subjectlidocaineen
dc.subjectclonidineen
dc.subjectepinephrineen
dc.subjectintraoral block anaesthesiaen
dc.titleComparison of clonidine and epinephrine in lidocaine anaesthesia for lower third molar surgeryen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractТодоровић, Л; Брковић, Божидар; Стојић, Д;
dc.citation.volume34
dc.citation.issue4
dc.citation.spage401
dc.citation.epage406
dc.citation.other34(4): 401-406
dc.citation.rankM22
dc.identifier.wos000229449100012
dc.identifier.doi10.1016/j.ijom.2004.06.014
dc.identifier.pmid16053850
dc.identifier.scopus2-s2.0-18244362799
dc.identifier.rcubconv_2691
dc.type.versionpublishedVersion


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