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Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome
dc.creator | Jekić, B. | |
dc.creator | Novaković, I. | |
dc.creator | Luković, L | |
dc.creator | Kuzmanović, M | |
dc.creator | Popović, Branka | |
dc.creator | Milašin, Jelena | |
dc.creator | Bunjevacki, G | |
dc.creator | Damnjanović, Tatjana | |
dc.creator | Cvjetičanin, S | |
dc.creator | Bunjevački, Vera | |
dc.date.accessioned | 2020-07-02T12:12:36Z | |
dc.date.available | 2020-07-02T12:12:36Z | |
dc.date.issued | 2006 | |
dc.identifier.issn | 0165-4608 | |
dc.identifier.uri | https://smile.stomf.bg.ac.rs/handle/123456789/1314 | |
dc.description.abstract | Myelodysplastic syndromes (MDS) are rare disorders in children. Molecular mechanisims underlying MDS in children are not yet completely understood. Considering the role of FMS and TP53 gene mutations in adult MDS patients, we analyzed nnutations of these genes in a cohort of 35 children with MDS. Single-strand conformation polymorphism polymerase chain reaction analysis performed on FMS codon 969 and TP53 exons 5-9 showed no mutations in the analyzed sequences. Our results Suggest that molecular mechanisms of MDS evolution in children are different from those in adults. | en |
dc.publisher | Elsevier Science Inc, New York | |
dc.rights | restrictedAccess | |
dc.source | Cancer Genetics & Cytogenetics | |
dc.title | Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Буњевачки, Вера; Новаковић, И; Јекић, Б; Луковић, Л; Кузмановић, М; Цвјетичанин, С; Дамњановић, Татјана; Буњевацки, Г; Милашин, Јелена; Поповић, Бранка; | |
dc.citation.volume | 166 | |
dc.citation.issue | 2 | |
dc.citation.spage | 163 | |
dc.citation.epage | 165 | |
dc.citation.other | 166(2): 163-165 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000237174400011 | |
dc.identifier.doi | 10.1016/j.cancergencyto.2005.11.003 | |
dc.identifier.pmid | 16631474 | |
dc.identifier.scopus | 2-s2.0-33646073109 | |
dc.type.version | publishedVersion |