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dc.creatorVukadinović, Miroslav
dc.creatorJezdić, Zoran
dc.creatorPetrović, Milan
dc.creatorMedenica, Ljiljana M.
dc.creatorLens, Marko
dc.date.accessioned2020-07-02T12:14:45Z
dc.date.available2020-07-02T12:14:45Z
dc.date.issued2007
dc.identifier.issn0278-2391
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/1347
dc.description.abstractBackground: The most common type of lip carcinoma is squamous cell carcinoma (SCC), accounting for approximately 90% of all oral malignancies. Currently, surgery and/or radiotherapy are considered the standards of care for SCC of the lip. Materials and Methods: We retrospectively analyzed medical records of patients diagnosed with SCC of the lip at the Clinic for Maxillofacial surgery at University of Belgrade (Belgrade, Serbia) during a period between 1991 and 2000. Results: A total of 223 patients with SCC of the lip were diagnosed and treated during a 10-year period. The overall male-to-female ratio was 5 to 0. The most frequently affected site was the lower lip (92.8%,). Mean diameter of the tumor was 30.1 mm (range, 5 to 80 full Neck lymph node metastases at presentation was detected in 26.5% of patients, who subsequently underwent neck dissection. We observed a linear trend in the association between the size of the tumor and the clinical stage of the neck (chi(2) = 15.1; df = 1; P lt .0001). Different surgical techniques were used for reconstruction of the lip defect after tumor removal. After a median follow-up of 56 months (range, 15 to 78 months), local recurrence occurred in 10.8% of patients while regional metastases developed in 4.5% of patients. Mortality from SCC of the lip was only 2.2%. Conclusion: SCC of the lip generally has a favorable outcome. Recently, there have been no major advances in lip reconstruction but rather continued improvement on accepted techniques. Early detection is essential for the successful treatment of SCC of the lip, which requires a multidisciplinary approach.en
dc.publisherW B Saunders Co-Elsevier Inc, Philadelphia
dc.rightsrestrictedAccess
dc.sourceJournal of Oral & Maxillofacial Surgery
dc.titleSurgical management of squamous cell carcinoma of the lip: Analysis of a 10-year experience in 223 patientsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractВукадиновић, Мирослав; Ленс, Марко; Меденица, Љиљана М.; Петровић, Милан; Јездић, Зоран;
dc.citation.volume65
dc.citation.issue4
dc.citation.spage675
dc.citation.epage679
dc.citation.other65(4): 675-679
dc.citation.rankM22
dc.identifier.wos000245385500014
dc.identifier.doi10.1016/j.joms.2006.03.054
dc.identifier.pmid17368363
dc.identifier.scopus2-s2.0-33947281431
dc.identifier.rcubconv_2732
dc.type.versionpublishedVersion


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