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The concentration of TNF-alpha correlate with number of inflammatory cells and degree of vascularization in radicular cysts

Authorized Users Only
2008
Authors
Jurišić, Vladimir
Terzić, T.
Čolić, Snježana
Jurišić, Milan
Article (Published version)
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Abstract
OBJECTIVE: To correlate values of tumor necrosis factor-alpha (TNF-alpha) depending on the count of inflammatory cells with degree of vascularization in cystic fluid of radicular cysts. MATERIAL AND METHODS: We investigated TNF-alpha concentration in 43 radicular cysts obtained from patients undergoing surgery, under local anaesthesia, and after aspiration of cystic fluid from non-ruptured cysts by enzyme-linked immunosorbent assay assay in respect of different clinical parameters as well as by histomorphometric analyses. RESULTS: Significantly higher concentration of TNF-alpha is associated with smaller radicular cysts, higher protein concentration in cystic fluid as well as with higher presence of inflammatory cells, and increased degree of vascularization in pericystic tissues and cyst wall thickness. CONCLUSIONS: We believe that determination of TNF-alpha in cystic fluid simultaneously with other parameters can be an additional parameter for clinical diagnosis of inflammed cysts.
Keywords:
TNF-alpha / radicular cysts / immunohistochemistry / inflammatory cells / vascularisation / inflammation
Source:
Oral Diseases, 2008, 14, 7, 600-605
Publisher:
  • Wiley, Hoboken

DOI: 10.1111/j.1601-0825.2007.01426.x

ISSN: 1354-523X

PubMed: 18221459

WoS: 000259684700004

Scopus: 2-s2.0-53149083403
[ Google Scholar ]
41
40
URI
https://smile.stomf.bg.ac.rs/handle/123456789/1445
Collections
  • Radovi istraživača
Institution/Community
Stomatološki fakultet
TY  - JOUR
AU  - Jurišić, Vladimir
AU  - Terzić, T.
AU  - Čolić, Snježana
AU  - Jurišić, Milan
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1445
AB  - OBJECTIVE: To correlate values of tumor necrosis factor-alpha (TNF-alpha) depending on the count of inflammatory cells with degree of vascularization in cystic fluid of radicular cysts. MATERIAL AND METHODS: We investigated TNF-alpha concentration in 43 radicular cysts obtained from patients undergoing surgery, under local anaesthesia, and after aspiration of cystic fluid from non-ruptured cysts by enzyme-linked immunosorbent assay assay in respect of different clinical parameters as well as by histomorphometric analyses. RESULTS: Significantly higher concentration of TNF-alpha is associated with smaller radicular cysts, higher protein concentration in cystic fluid as well as with higher presence of inflammatory cells, and increased degree of vascularization in pericystic tissues and cyst wall thickness. CONCLUSIONS: We believe that determination of TNF-alpha in cystic fluid simultaneously with other parameters can be an additional parameter for clinical diagnosis of inflammed cysts.
PB  - Wiley, Hoboken
T2  - Oral Diseases
T1  - The concentration of TNF-alpha correlate with number of inflammatory cells and degree of vascularization in radicular cysts
VL  - 14
IS  - 7
SP  - 600
EP  - 605
DO  - 10.1111/j.1601-0825.2007.01426.x
ER  - 
@article{
author = "Jurišić, Vladimir and Terzić, T. and Čolić, Snježana and Jurišić, Milan",
year = "2008",
abstract = "OBJECTIVE: To correlate values of tumor necrosis factor-alpha (TNF-alpha) depending on the count of inflammatory cells with degree of vascularization in cystic fluid of radicular cysts. MATERIAL AND METHODS: We investigated TNF-alpha concentration in 43 radicular cysts obtained from patients undergoing surgery, under local anaesthesia, and after aspiration of cystic fluid from non-ruptured cysts by enzyme-linked immunosorbent assay assay in respect of different clinical parameters as well as by histomorphometric analyses. RESULTS: Significantly higher concentration of TNF-alpha is associated with smaller radicular cysts, higher protein concentration in cystic fluid as well as with higher presence of inflammatory cells, and increased degree of vascularization in pericystic tissues and cyst wall thickness. CONCLUSIONS: We believe that determination of TNF-alpha in cystic fluid simultaneously with other parameters can be an additional parameter for clinical diagnosis of inflammed cysts.",
publisher = "Wiley, Hoboken",
journal = "Oral Diseases",
title = "The concentration of TNF-alpha correlate with number of inflammatory cells and degree of vascularization in radicular cysts",
volume = "14",
number = "7",
pages = "600-605",
doi = "10.1111/j.1601-0825.2007.01426.x"
}
Jurišić, V., Terzić, T., Čolić, S.,& Jurišić, M.. (2008). The concentration of TNF-alpha correlate with number of inflammatory cells and degree of vascularization in radicular cysts. in Oral Diseases
Wiley, Hoboken., 14(7), 600-605.
https://doi.org/10.1111/j.1601-0825.2007.01426.x
Jurišić V, Terzić T, Čolić S, Jurišić M. The concentration of TNF-alpha correlate with number of inflammatory cells and degree of vascularization in radicular cysts. in Oral Diseases. 2008;14(7):600-605.
doi:10.1111/j.1601-0825.2007.01426.x .
Jurišić, Vladimir, Terzić, T., Čolić, Snježana, Jurišić, Milan, "The concentration of TNF-alpha correlate with number of inflammatory cells and degree of vascularization in radicular cysts" in Oral Diseases, 14, no. 7 (2008):600-605,
https://doi.org/10.1111/j.1601-0825.2007.01426.x . .

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