Burning mouth syndrome (BMS) is an intraoral burning sensation for which no medical or dental cause can be found. Recent studies suggest that primary neuropathic dysfunction might be involved in the pathogenesis of BMS. Calcitonin gene-related peptide (CGRP) plays an important role in the development of pain and serves as a biological marker of trigeminovascular activation. The aim of this study was to determine the levels of CGRP in the saliva of BMS patients and estimate the trigeminovascular activation in BMS. CGRP levels were measured, by RIA method in 78 BMS patients and 16 healthy subjects. The levels of CGRP were non-significantly decreased in BMS patients in comparison to healthy subjects. These results suggest that trigeminal nerve degeneration may be the underlying cause of BMS.
TY - JOUR
AU - Zidverc-Trajković, Jasna
AU - Stanimirović, Dragan
AU - Obrenović, Radmila
AU - Tajti, Janos
AU - Vecsei, Laszlo
AU - Gardi, Janos
AU - Nemeth, Jozsef
AU - Mijajlović, Milija
AU - Šternić, Nadežda
AU - Janković, Ljiljana
PY - 2009
UR - https://smile.stomf.bg.ac.rs/handle/123456789/1513
AB - Burning mouth syndrome (BMS) is an intraoral burning sensation for which no medical or dental cause can be found. Recent studies suggest that primary neuropathic dysfunction might be involved in the pathogenesis of BMS. Calcitonin gene-related peptide (CGRP) plays an important role in the development of pain and serves as a biological marker of trigeminovascular activation. The aim of this study was to determine the levels of CGRP in the saliva of BMS patients and estimate the trigeminovascular activation in BMS. CGRP levels were measured, by RIA method in 78 BMS patients and 16 healthy subjects. The levels of CGRP were non-significantly decreased in BMS patients in comparison to healthy subjects. These results suggest that trigeminal nerve degeneration may be the underlying cause of BMS.
PB - Wiley, Hoboken
T2 - Journal of Oral Pathology & Medicine
T1 - Calcitonin gene-related peptide levels in saliva of patients with burning mouth syndrome
VL - 38
IS - 1
SP - 29
EP - 33
DO - 10.1111/j.1600-0714.2008.00721.x
ER -
@article{
author = "Zidverc-Trajković, Jasna and Stanimirović, Dragan and Obrenović, Radmila and Tajti, Janos and Vecsei, Laszlo and Gardi, Janos and Nemeth, Jozsef and Mijajlović, Milija and Šternić, Nadežda and Janković, Ljiljana",
year = "2009",
abstract = "Burning mouth syndrome (BMS) is an intraoral burning sensation for which no medical or dental cause can be found. Recent studies suggest that primary neuropathic dysfunction might be involved in the pathogenesis of BMS. Calcitonin gene-related peptide (CGRP) plays an important role in the development of pain and serves as a biological marker of trigeminovascular activation. The aim of this study was to determine the levels of CGRP in the saliva of BMS patients and estimate the trigeminovascular activation in BMS. CGRP levels were measured, by RIA method in 78 BMS patients and 16 healthy subjects. The levels of CGRP were non-significantly decreased in BMS patients in comparison to healthy subjects. These results suggest that trigeminal nerve degeneration may be the underlying cause of BMS.",
publisher = "Wiley, Hoboken",
journal = "Journal of Oral Pathology & Medicine",
title = "Calcitonin gene-related peptide levels in saliva of patients with burning mouth syndrome",
volume = "38",
number = "1",
pages = "29-33",
doi = "10.1111/j.1600-0714.2008.00721.x"
}
Zidverc-Trajković, J., Stanimirović, D., Obrenović, R., Tajti, J., Vecsei, L., Gardi, J., Nemeth, J., Mijajlović, M., Šternić, N.,& Janković, L.. (2009). Calcitonin gene-related peptide levels in saliva of patients with burning mouth syndrome. in Journal of Oral Pathology & Medicine
Wiley, Hoboken., 38(1), 29-33.
https://doi.org/10.1111/j.1600-0714.2008.00721.x
Zidverc-Trajković J, Stanimirović D, Obrenović R, Tajti J, Vecsei L, Gardi J, Nemeth J, Mijajlović M, Šternić N, Janković L. Calcitonin gene-related peptide levels in saliva of patients with burning mouth syndrome. in Journal of Oral Pathology & Medicine. 2009;38(1):29-33.
doi:10.1111/j.1600-0714.2008.00721.x .
Zidverc-Trajković, Jasna, Stanimirović, Dragan, Obrenović, Radmila, Tajti, Janos, Vecsei, Laszlo, Gardi, Janos, Nemeth, Jozsef, Mijajlović, Milija, Šternić, Nadežda, Janković, Ljiljana, "Calcitonin gene-related peptide levels in saliva of patients with burning mouth syndrome" in Journal of Oral Pathology & Medicine, 38, no. 1 (2009):29-33,
https://doi.org/10.1111/j.1600-0714.2008.00721.x . .
