This study evaluated the prevalence of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) in peri-implantitis and mucositis sites and the correlation between herpesvirus and clinical parameters. Fifty-six dental implants (mean time of loading, 4.27 +/- 1.6 years) were evaluated (20 peri-implantitis, 18 mucositis, 18 healthy pen-implant sites.) The clinical parameters assessed were: visible plaque index (PI), bleeding on probing (BOP), suppuration (SUP), probing depth (PD). A polymerase chain reaction assay identified HCMV and EBV in subgingival plaque samples. The percent of sites with plaque and BOP was significantly higher around mucositis and peri-implantitis compared with healthy implants (p lt 0.05). The mean PD around the implants was significantly higher in peri-implantitis, followed by mucositis and healthy implants (p lt 0.05). HCMV was detected in 13 (65%) and EBV in 9 (45%) of the 20 peri-implantitis sites. HCMV was found in 1 of the 18 (6%) healthy periodontal si...tes and EBV in 2 (11 %). A statistically significant correlation was found between presence of HCMV and EBV subgingivally and clinical parameters of peri-implantitis and healthy sites. These results confirm the high prevalence of HCMV and EBV in subgingival plaque of peri-implantitis sites and suggest the viruses have a possible active pathogenic role in peri-implantitis.
Keywords:
herpesviruses / EBV / HCMV / peri-implantitis
Source:
International Journal of Oral & Maxillofacial Surgery, 2011, 40, 3, 271-276
TY - JOUR
AU - Janković, Saša
AU - Aleksić, Zoran
AU - Dimitrijević, B.
AU - Leković, Vojislav
AU - Camargo, Paulo
AU - Kenney, Barrie
PY - 2011
UR - https://smile.stomf.bg.ac.rs/handle/123456789/1623
AB - This study evaluated the prevalence of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) in peri-implantitis and mucositis sites and the correlation between herpesvirus and clinical parameters. Fifty-six dental implants (mean time of loading, 4.27 +/- 1.6 years) were evaluated (20 peri-implantitis, 18 mucositis, 18 healthy pen-implant sites.) The clinical parameters assessed were: visible plaque index (PI), bleeding on probing (BOP), suppuration (SUP), probing depth (PD). A polymerase chain reaction assay identified HCMV and EBV in subgingival plaque samples. The percent of sites with plaque and BOP was significantly higher around mucositis and peri-implantitis compared with healthy implants (p lt 0.05). The mean PD around the implants was significantly higher in peri-implantitis, followed by mucositis and healthy implants (p lt 0.05). HCMV was detected in 13 (65%) and EBV in 9 (45%) of the 20 peri-implantitis sites. HCMV was found in 1 of the 18 (6%) healthy periodontal sites and EBV in 2 (11 %). A statistically significant correlation was found between presence of HCMV and EBV subgingivally and clinical parameters of peri-implantitis and healthy sites. These results confirm the high prevalence of HCMV and EBV in subgingival plaque of peri-implantitis sites and suggest the viruses have a possible active pathogenic role in peri-implantitis.
PB - Churchill Livingstone, Edinburgh
T2 - International Journal of Oral & Maxillofacial Surgery
T1 - Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study
VL - 40
IS - 3
SP - 271
EP - 276
DO - 10.1016/j.ijom.2010.11.004
ER -
@article{
author = "Janković, Saša and Aleksić, Zoran and Dimitrijević, B. and Leković, Vojislav and Camargo, Paulo and Kenney, Barrie",
year = "2011",
abstract = "This study evaluated the prevalence of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) in peri-implantitis and mucositis sites and the correlation between herpesvirus and clinical parameters. Fifty-six dental implants (mean time of loading, 4.27 +/- 1.6 years) were evaluated (20 peri-implantitis, 18 mucositis, 18 healthy pen-implant sites.) The clinical parameters assessed were: visible plaque index (PI), bleeding on probing (BOP), suppuration (SUP), probing depth (PD). A polymerase chain reaction assay identified HCMV and EBV in subgingival plaque samples. The percent of sites with plaque and BOP was significantly higher around mucositis and peri-implantitis compared with healthy implants (p lt 0.05). The mean PD around the implants was significantly higher in peri-implantitis, followed by mucositis and healthy implants (p lt 0.05). HCMV was detected in 13 (65%) and EBV in 9 (45%) of the 20 peri-implantitis sites. HCMV was found in 1 of the 18 (6%) healthy periodontal sites and EBV in 2 (11 %). A statistically significant correlation was found between presence of HCMV and EBV subgingivally and clinical parameters of peri-implantitis and healthy sites. These results confirm the high prevalence of HCMV and EBV in subgingival plaque of peri-implantitis sites and suggest the viruses have a possible active pathogenic role in peri-implantitis.",
publisher = "Churchill Livingstone, Edinburgh",
journal = "International Journal of Oral & Maxillofacial Surgery",
title = "Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study",
volume = "40",
number = "3",
pages = "271-276",
doi = "10.1016/j.ijom.2010.11.004"
}
Janković, S., Aleksić, Z., Dimitrijević, B., Leković, V., Camargo, P.,& Kenney, B.. (2011). Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study. in International Journal of Oral & Maxillofacial Surgery
Churchill Livingstone, Edinburgh., 40(3), 271-276.
https://doi.org/10.1016/j.ijom.2010.11.004
Janković S, Aleksić Z, Dimitrijević B, Leković V, Camargo P, Kenney B. Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study. in International Journal of Oral & Maxillofacial Surgery. 2011;40(3):271-276.
doi:10.1016/j.ijom.2010.11.004 .
Janković, Saša, Aleksić, Zoran, Dimitrijević, B., Leković, Vojislav, Camargo, Paulo, Kenney, Barrie, "Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study" in International Journal of Oral & Maxillofacial Surgery, 40, no. 3 (2011):271-276,
https://doi.org/10.1016/j.ijom.2010.11.004 . .
