Приказ основних података о документу

dc.creatorJekić, Biljana
dc.creatorBunjevački, Vera
dc.creatorDobričić, Valerija
dc.creatorNovaković, Ivana
dc.creatorMilašin, Jelena
dc.creatorPopović, Branka
dc.creatorDamnjanović, Tatjana
dc.creatorMaksimović, Nela
dc.creatorPerović, V.
dc.creatorLuković, Ljiljana
dc.date.accessioned2020-07-02T12:33:38Z
dc.date.available2020-07-02T12:33:38Z
dc.date.issued2011
dc.identifier.issn0354-4664
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/1635
dc.description.abstractMyelodysplastic syndromes (MDS) are rare in children and only a few studies have analyzed their molecular mechanisms. The NPM1 gene encodes for nucleophosmin (NPM) which regulates hematopoiesis. Mutations in exon 12 of the NPM1 cause the nucleophosmin cytoplasmic dislocation and disrupt its functions. We have analyzed mutations of the NPM1 gene in archival bone marrow samples from 17 children with MDS and detected, in one patient, transition C to T in codon 293. To the best of our knowledge, this is the first analysis of NPM1 mutations in childhood MDS and the very first missense mutation of the NPM1 gene reported so far.en
dc.publisherSrpsko biološko društvo, Beograd, i dr.
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceArchives of Biological Sciences
dc.subjectMyelodysplastic syndromesen
dc.subjectnucleophosminen
dc.subjectNPM1 mutationen
dc.subjectchildrenen
dc.titleNPM1 gene mutations in children with Myelodysplastic syndromesen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractДобричић, Валерија; Перовић, В.; Поповић, Бранка; Буњевачки, Вера; Дамњановић, Татјана; Луковић, Љиљана; Милашин, Јелена; Новаковић, Ивана; Јекић, Биљана; Максимовић, Нела;
dc.citation.volume63
dc.citation.issue3
dc.citation.spage649
dc.citation.epage653
dc.citation.other63(3): 649-653
dc.citation.rankM23
dc.identifier.wos000294400500017
dc.identifier.doi10.2298/ABS1103649J
dc.identifier.scopus2-s2.0-79961178698
dc.identifier.fulltexthttps://smile.stomf.bg.ac.rs/bitstream/id/389/1630.pdf
dc.type.versionpublishedVersion


Документи

Thumbnail

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу