Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation
Само за регистроване кориснике
2012
Аутори
Brković, BožidarPrasad, Hari S.
Rohrer, Michael D.
Konandreas, George
Agrogiannis, George
Antunović, Dragana
Sandor, George K.B.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The aim of this study was to investigate the healing of human extraction sockets filled with beta-tricalcium phosphate and type I collagen (beta-TCP/Clg) cones with or without a barrier membrane. Twenty patients were divided in two groups: (A) beta-TCP/Clg non-membrane and (B) beta-TCP/Clg + barrier membrane. Clinical examination and biopsies from the grafted sites were collected 9 months later. Bone samples were analyzed using histomorphometry and immunohistochemistry. The horizontal dimension of the alveolar ridge was significantly reduced 9 months after socket preservation in the non-membrane group. There was bone formation with no significant differences between the two groups in the areas occupied by new bone (A = 42.4%; B = 45.3%), marrow (A = 42.7%; B = 35.7%), or residual graft (A = 9.7%; B = 12.5%). Immunohistochemistry revealed osteonectin expression in both groups. Both groups demonstrated sufficient amounts of vital bone and socket morphology to support dental implant place...ment after the 9-month healing period. A future trial to evaluate the alveolar outcomes at an earlier 6-month time point rather than the 9 months used in this study would be of interest.
Кључне речи:
Socket preservation / Beta-tricalcium phosphate / Collagen type I / Barrier membrane / Histomorphometry / ImmunohistochemistryИзвор:
Clinical Oral Investigations, 2012, 16, 2, 581-590Издавач:
- Springer Heidelberg, Heidelberg
Финансирање / пројекти:
- Septodont, France [2207-2006]
DOI: 10.1007/s00784-011-0531-1
ISSN: 1432-6981
PubMed: 21369794
WoS: 000301786700030
Scopus: 2-s2.0-84858703437
Колекције
Институција/група
Stomatološki fakultetTY - JOUR AU - Brković, Božidar AU - Prasad, Hari S. AU - Rohrer, Michael D. AU - Konandreas, George AU - Agrogiannis, George AU - Antunović, Dragana AU - Sandor, George K.B. PY - 2012 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1749 AB - The aim of this study was to investigate the healing of human extraction sockets filled with beta-tricalcium phosphate and type I collagen (beta-TCP/Clg) cones with or without a barrier membrane. Twenty patients were divided in two groups: (A) beta-TCP/Clg non-membrane and (B) beta-TCP/Clg + barrier membrane. Clinical examination and biopsies from the grafted sites were collected 9 months later. Bone samples were analyzed using histomorphometry and immunohistochemistry. The horizontal dimension of the alveolar ridge was significantly reduced 9 months after socket preservation in the non-membrane group. There was bone formation with no significant differences between the two groups in the areas occupied by new bone (A = 42.4%; B = 45.3%), marrow (A = 42.7%; B = 35.7%), or residual graft (A = 9.7%; B = 12.5%). Immunohistochemistry revealed osteonectin expression in both groups. Both groups demonstrated sufficient amounts of vital bone and socket morphology to support dental implant placement after the 9-month healing period. A future trial to evaluate the alveolar outcomes at an earlier 6-month time point rather than the 9 months used in this study would be of interest. PB - Springer Heidelberg, Heidelberg T2 - Clinical Oral Investigations T1 - Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation VL - 16 IS - 2 SP - 581 EP - 590 DO - 10.1007/s00784-011-0531-1 ER -
@article{ author = "Brković, Božidar and Prasad, Hari S. and Rohrer, Michael D. and Konandreas, George and Agrogiannis, George and Antunović, Dragana and Sandor, George K.B.", year = "2012", abstract = "The aim of this study was to investigate the healing of human extraction sockets filled with beta-tricalcium phosphate and type I collagen (beta-TCP/Clg) cones with or without a barrier membrane. Twenty patients were divided in two groups: (A) beta-TCP/Clg non-membrane and (B) beta-TCP/Clg + barrier membrane. Clinical examination and biopsies from the grafted sites were collected 9 months later. Bone samples were analyzed using histomorphometry and immunohistochemistry. The horizontal dimension of the alveolar ridge was significantly reduced 9 months after socket preservation in the non-membrane group. There was bone formation with no significant differences between the two groups in the areas occupied by new bone (A = 42.4%; B = 45.3%), marrow (A = 42.7%; B = 35.7%), or residual graft (A = 9.7%; B = 12.5%). Immunohistochemistry revealed osteonectin expression in both groups. Both groups demonstrated sufficient amounts of vital bone and socket morphology to support dental implant placement after the 9-month healing period. A future trial to evaluate the alveolar outcomes at an earlier 6-month time point rather than the 9 months used in this study would be of interest.", publisher = "Springer Heidelberg, Heidelberg", journal = "Clinical Oral Investigations", title = "Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation", volume = "16", number = "2", pages = "581-590", doi = "10.1007/s00784-011-0531-1" }
Brković, B., Prasad, H. S., Rohrer, M. D., Konandreas, G., Agrogiannis, G., Antunović, D.,& Sandor, G. K.B.. (2012). Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation. in Clinical Oral Investigations Springer Heidelberg, Heidelberg., 16(2), 581-590. https://doi.org/10.1007/s00784-011-0531-1
Brković B, Prasad HS, Rohrer MD, Konandreas G, Agrogiannis G, Antunović D, Sandor GK. Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation. in Clinical Oral Investigations. 2012;16(2):581-590. doi:10.1007/s00784-011-0531-1 .
Brković, Božidar, Prasad, Hari S., Rohrer, Michael D., Konandreas, George, Agrogiannis, George, Antunović, Dragana, Sandor, George K.B., "Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation" in Clinical Oral Investigations, 16, no. 2 (2012):581-590, https://doi.org/10.1007/s00784-011-0531-1 . .