Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells
Само за регистроване кориснике
2013
Аутори
Miletić, MajaMojsilović, S.
Okic-Đorđević, Ivana
Maletić, D.
Puač, Nevena
Lazović, Saša
Malović, Gordana
Milenković, P.
Petrović, Zoran Lj.
Bugarski, Diana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Here we investigate the influences of non-thermal atmospheric plasma on human mesenchymal stem cells isolated from periodontal ligament (hPDL-MSCs). A specially redesigned plasma needle was used as the source of low-temperature plasma and its effects on different hPDL-MSC functions were investigated. Cell cultures were obtained from extracted normal impacted third molars and characterized for their phenotype and multi-potential differentiation. The hPDL-MSCs possessed all the typical MSC properties, including clonogenic ability, high proliferation rate, specific phenotype and multilineage differentiation. The data regarding the interaction of plasma with hPDL-MSCs demonstrated that plasma treatment inhibited the migration of hPDL-MSCs and induced some detachment, while not affecting their viability. Additionally, plasma significantly attenuated hPDL-MSCs' proliferation, but promoted their osteogenic differentiation. The results of this study indicated that a non-thermal plasma offers s...pecific activity with non-destructive properties that can be advantageous for future dental applications.
Извор:
Journal of Physics D - Applied Physics, 2013, 46, 34Издавач:
- Iop Publishing Ltd, Bristol
Финансирање / пројекти:
- Регенеративни и модулаторни потенцијал адултних матичних ћелија (RS-MESTD-Basic Research (BR or ON)-175062)
- Фундаментални процеси и примене транспорта честица у неравнотежним плазмама, траповима и наноструктурама (RS-MESTD-Basic Research (BR or ON)-171037)
- Примене нискотемпературних плазми у биомедицини, заштити човекове околине и нанотехнологијама (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41011)
DOI: 10.1088/0022-3727/46/34/345401
ISSN: 0022-3727
WoS: 000323062400017
Scopus: 2-s2.0-84882360715
Колекције
Институција/група
Stomatološki fakultetTY - JOUR AU - Miletić, Maja AU - Mojsilović, S. AU - Okic-Đorđević, Ivana AU - Maletić, D. AU - Puač, Nevena AU - Lazović, Saša AU - Malović, Gordana AU - Milenković, P. AU - Petrović, Zoran Lj. AU - Bugarski, Diana PY - 2013 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1833 AB - Here we investigate the influences of non-thermal atmospheric plasma on human mesenchymal stem cells isolated from periodontal ligament (hPDL-MSCs). A specially redesigned plasma needle was used as the source of low-temperature plasma and its effects on different hPDL-MSC functions were investigated. Cell cultures were obtained from extracted normal impacted third molars and characterized for their phenotype and multi-potential differentiation. The hPDL-MSCs possessed all the typical MSC properties, including clonogenic ability, high proliferation rate, specific phenotype and multilineage differentiation. The data regarding the interaction of plasma with hPDL-MSCs demonstrated that plasma treatment inhibited the migration of hPDL-MSCs and induced some detachment, while not affecting their viability. Additionally, plasma significantly attenuated hPDL-MSCs' proliferation, but promoted their osteogenic differentiation. The results of this study indicated that a non-thermal plasma offers specific activity with non-destructive properties that can be advantageous for future dental applications. PB - Iop Publishing Ltd, Bristol T2 - Journal of Physics D - Applied Physics T1 - Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells VL - 46 IS - 34 DO - 10.1088/0022-3727/46/34/345401 ER -
@article{ author = "Miletić, Maja and Mojsilović, S. and Okic-Đorđević, Ivana and Maletić, D. and Puač, Nevena and Lazović, Saša and Malović, Gordana and Milenković, P. and Petrović, Zoran Lj. and Bugarski, Diana", year = "2013", abstract = "Here we investigate the influences of non-thermal atmospheric plasma on human mesenchymal stem cells isolated from periodontal ligament (hPDL-MSCs). A specially redesigned plasma needle was used as the source of low-temperature plasma and its effects on different hPDL-MSC functions were investigated. Cell cultures were obtained from extracted normal impacted third molars and characterized for their phenotype and multi-potential differentiation. The hPDL-MSCs possessed all the typical MSC properties, including clonogenic ability, high proliferation rate, specific phenotype and multilineage differentiation. The data regarding the interaction of plasma with hPDL-MSCs demonstrated that plasma treatment inhibited the migration of hPDL-MSCs and induced some detachment, while not affecting their viability. Additionally, plasma significantly attenuated hPDL-MSCs' proliferation, but promoted their osteogenic differentiation. The results of this study indicated that a non-thermal plasma offers specific activity with non-destructive properties that can be advantageous for future dental applications.", publisher = "Iop Publishing Ltd, Bristol", journal = "Journal of Physics D - Applied Physics", title = "Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells", volume = "46", number = "34", doi = "10.1088/0022-3727/46/34/345401" }
Miletić, M., Mojsilović, S., Okic-Đorđević, I., Maletić, D., Puač, N., Lazović, S., Malović, G., Milenković, P., Petrović, Z. Lj.,& Bugarski, D.. (2013). Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells. in Journal of Physics D - Applied Physics Iop Publishing Ltd, Bristol., 46(34). https://doi.org/10.1088/0022-3727/46/34/345401
Miletić M, Mojsilović S, Okic-Đorđević I, Maletić D, Puač N, Lazović S, Malović G, Milenković P, Petrović ZL, Bugarski D. Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells. in Journal of Physics D - Applied Physics. 2013;46(34). doi:10.1088/0022-3727/46/34/345401 .
Miletić, Maja, Mojsilović, S., Okic-Đorđević, Ivana, Maletić, D., Puač, Nevena, Lazović, Saša, Malović, Gordana, Milenković, P., Petrović, Zoran Lj., Bugarski, Diana, "Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells" in Journal of Physics D - Applied Physics, 46, no. 34 (2013), https://doi.org/10.1088/0022-3727/46/34/345401 . .