Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment
Samo za registrovane korisnike
2013
Autori
Janković, SašaAleksić, Zoran
Dimitrijević, Božidar
Camargo, Paulo
Kenney, Barrie
Leković, Vojislav
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Risk factors such as smoking, genetic factors, and tissue biotype play an important role in the etiology, predictability, and long-term stability of gingival recession treatment. This study was designed to evaluate the influence of interleukin 1 (IL-1) polymorphism and smoking on the stability of gingival recession treatment after 1 and 3 years. All patients (n = 55) were treated for type I and II recession defects using a connective tissue graft. Clinical evaluations were performed, which included assessment of vertical recession depth, gingival inflammation, and clinical attachment level. A fingerstick blood sample was collected using specially provided DNA filter paper and mailed for processing in a laboratory using polymerase chain reaction-based methodology. The results indicated that 19 subjects were genotype positive (34.5%). Treatment of the localized recessions was effective and provided a similar amount of coverage in genotype-positive and genotype-negative subjects within sm...oking and nonsmoking groups after 1 year. In a 3-year period, nonsmoking patients with positive IL-1 genotype lost approximately 20% of the root coverage gained at 1 year and were almost four times more inferior compared with genotype-negative patients. Patients who smoked and had a positive IL-1 genotype lost approximately 35% of the gained root coverage. IL-1 polymorphism and smoking habit did not affect gingival recession treatment at 1 year but had a great impact on long-term stability.
Izvor:
International Journal of Periodontics & Restorative Dentistry, 2013, 33, 1, E16-E23Izdavač:
- Quintessence Publishing Co Inc, Hanover Park
DOI: 10.11607/prd.0823
ISSN: 0198-7569
PubMed: 23342354
WoS: 000320113400003
Scopus: 2-s2.0-84891885921
Kolekcije
Institucija/grupa
Stomatološki fakultetTY - JOUR AU - Janković, Saša AU - Aleksić, Zoran AU - Dimitrijević, Božidar AU - Camargo, Paulo AU - Kenney, Barrie AU - Leković, Vojislav PY - 2013 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1844 AB - Risk factors such as smoking, genetic factors, and tissue biotype play an important role in the etiology, predictability, and long-term stability of gingival recession treatment. This study was designed to evaluate the influence of interleukin 1 (IL-1) polymorphism and smoking on the stability of gingival recession treatment after 1 and 3 years. All patients (n = 55) were treated for type I and II recession defects using a connective tissue graft. Clinical evaluations were performed, which included assessment of vertical recession depth, gingival inflammation, and clinical attachment level. A fingerstick blood sample was collected using specially provided DNA filter paper and mailed for processing in a laboratory using polymerase chain reaction-based methodology. The results indicated that 19 subjects were genotype positive (34.5%). Treatment of the localized recessions was effective and provided a similar amount of coverage in genotype-positive and genotype-negative subjects within smoking and nonsmoking groups after 1 year. In a 3-year period, nonsmoking patients with positive IL-1 genotype lost approximately 20% of the root coverage gained at 1 year and were almost four times more inferior compared with genotype-negative patients. Patients who smoked and had a positive IL-1 genotype lost approximately 35% of the gained root coverage. IL-1 polymorphism and smoking habit did not affect gingival recession treatment at 1 year but had a great impact on long-term stability. PB - Quintessence Publishing Co Inc, Hanover Park T2 - International Journal of Periodontics & Restorative Dentistry T1 - Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment VL - 33 IS - 1 SP - E16 EP - E23 DO - 10.11607/prd.0823 ER -
@article{ author = "Janković, Saša and Aleksić, Zoran and Dimitrijević, Božidar and Camargo, Paulo and Kenney, Barrie and Leković, Vojislav", year = "2013", abstract = "Risk factors such as smoking, genetic factors, and tissue biotype play an important role in the etiology, predictability, and long-term stability of gingival recession treatment. This study was designed to evaluate the influence of interleukin 1 (IL-1) polymorphism and smoking on the stability of gingival recession treatment after 1 and 3 years. All patients (n = 55) were treated for type I and II recession defects using a connective tissue graft. Clinical evaluations were performed, which included assessment of vertical recession depth, gingival inflammation, and clinical attachment level. A fingerstick blood sample was collected using specially provided DNA filter paper and mailed for processing in a laboratory using polymerase chain reaction-based methodology. The results indicated that 19 subjects were genotype positive (34.5%). Treatment of the localized recessions was effective and provided a similar amount of coverage in genotype-positive and genotype-negative subjects within smoking and nonsmoking groups after 1 year. In a 3-year period, nonsmoking patients with positive IL-1 genotype lost approximately 20% of the root coverage gained at 1 year and were almost four times more inferior compared with genotype-negative patients. Patients who smoked and had a positive IL-1 genotype lost approximately 35% of the gained root coverage. IL-1 polymorphism and smoking habit did not affect gingival recession treatment at 1 year but had a great impact on long-term stability.", publisher = "Quintessence Publishing Co Inc, Hanover Park", journal = "International Journal of Periodontics & Restorative Dentistry", title = "Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment", volume = "33", number = "1", pages = "E16-E23", doi = "10.11607/prd.0823" }
Janković, S., Aleksić, Z., Dimitrijević, B., Camargo, P., Kenney, B.,& Leković, V.. (2013). Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment. in International Journal of Periodontics & Restorative Dentistry Quintessence Publishing Co Inc, Hanover Park., 33(1), E16-E23. https://doi.org/10.11607/prd.0823
Janković S, Aleksić Z, Dimitrijević B, Camargo P, Kenney B, Leković V. Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment. in International Journal of Periodontics & Restorative Dentistry. 2013;33(1):E16-E23. doi:10.11607/prd.0823 .
Janković, Saša, Aleksić, Zoran, Dimitrijević, Božidar, Camargo, Paulo, Kenney, Barrie, Leković, Vojislav, "Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment" in International Journal of Periodontics & Restorative Dentistry, 33, no. 1 (2013):E16-E23, https://doi.org/10.11607/prd.0823 . .