Postoperative pain is common complication after daily dental care. Non-steroidal anti-inflammatory drugs are among most widely prescribed analgesics for management of postoperative pain. The analgesic effect of a non-steroidal antiinflammatory drug (NSAID) is related to its ability to inhibit prostaglandin synthesis. Ibuprofen (2-proprionic acid derivate) was discovered in the 1960s as a representative of NSAIDs. It is a peripherally acting analgesic with a potent anti-inflammatory action. An extensive retrospective analysis of randomized clinical trials conducted over the last 40 years demonstrated that ibuprofen is effective in moderate to severe postoperative pain for different indications in dentistry. In comparison to other NSAIDs, ibuprofen is characterized by its efficiency, safety and good tolerance. The aim of this article was to present the most important pharmacological and therapeutic characteristics and side effects of ibuprofen used for postoperative pain treatment in den...tistry.
Bol koji se javi nakon hirurške intervencije je vrlo česta komplikacija u svakodnevnoj stomatološkoj praksi. U suzbijanju (lečenju) postoperacionog bola najčešće se prepisuju nesteroidni antiinflamatorni lekovi (NSAIL). Njihov analgetski efekat se zasniva, pre svega, na sprečavanju sinteze prostaglandina. Ibuprofen (derivat 2-propionske kiseline) je predstavnik velike grupe NSAIL, a otkriven je 1960. godine. Ovaj analgetik deluje na periferne nervne završetke s izrazitim protivupalnim efektom. Opsežna retrospektivna analiza randomiziranih kliničkih istraživanja u proteklih 40 godina pokazala je da je ibuprofen efikasan u suzbijanju umerenog i izraženog postoperacionog bola kod različitih indikacija. Osim efikasnosti, ibuprofen se odlikuje dobrom podnošljivošću i sigurnošću u poređenju sa drugim NSAIL. Cilj ovog rada bio je da se ukaže na najznačajnije farmakološke i terapeutske odlike, kao i neželjena dejstva ibuprofena u lečenju postoperacionog bola pri različitim indikacijama u stoma...tologiji.
TY - JOUR
AU - Jakovljević, Aleksandar
AU - Lazić, Emira
AU - Perunović, Neda
AU - Nedeljković, Nenad
PY - 2014
UR - https://smile.stomf.bg.ac.rs/handle/123456789/1873
AB - Postoperative pain is common complication after daily dental care. Non-steroidal anti-inflammatory drugs are among most widely prescribed analgesics for management of postoperative pain. The analgesic effect of a non-steroidal antiinflammatory drug (NSAID) is related to its ability to inhibit prostaglandin synthesis. Ibuprofen (2-proprionic acid derivate) was discovered in the 1960s as a representative of NSAIDs. It is a peripherally acting analgesic with a potent anti-inflammatory action. An extensive retrospective analysis of randomized clinical trials conducted over the last 40 years demonstrated that ibuprofen is effective in moderate to severe postoperative pain for different indications in dentistry. In comparison to other NSAIDs, ibuprofen is characterized by its efficiency, safety and good tolerance. The aim of this article was to present the most important pharmacological and therapeutic characteristics and side effects of ibuprofen used for postoperative pain treatment in dentistry.
AB - Bol koji se javi nakon hirurške intervencije je vrlo česta komplikacija u svakodnevnoj stomatološkoj praksi. U suzbijanju (lečenju) postoperacionog bola najčešće se prepisuju nesteroidni antiinflamatorni lekovi (NSAIL). Njihov analgetski efekat se zasniva, pre svega, na sprečavanju sinteze prostaglandina. Ibuprofen (derivat 2-propionske kiseline) je predstavnik velike grupe NSAIL, a otkriven je 1960. godine. Ovaj analgetik deluje na periferne nervne završetke s izrazitim protivupalnim efektom. Opsežna retrospektivna analiza randomiziranih kliničkih istraživanja u proteklih 40 godina pokazala je da je ibuprofen efikasan u suzbijanju umerenog i izraženog postoperacionog bola kod različitih indikacija. Osim efikasnosti, ibuprofen se odlikuje dobrom podnošljivošću i sigurnošću u poređenju sa drugim NSAIL. Cilj ovog rada bio je da se ukaže na najznačajnije farmakološke i terapeutske odlike, kao i neželjena dejstva ibuprofena u lečenju postoperacionog bola pri različitim indikacijama u stomatologiji.
PB - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2 - Stomatološki glasnik Srbije
T1 - The use of ibuprofen in the treatment of postoperative pain in dentistry
T1 - Primena ibuprofena u suzbijanju postoperacionog bola u stomatologiji
VL - 61
IS - 3
SP - 134
EP - 141
DO - 10.2298/sgs1403134j
ER -
@article{
author = "Jakovljević, Aleksandar and Lazić, Emira and Perunović, Neda and Nedeljković, Nenad",
year = "2014",
abstract = "Postoperative pain is common complication after daily dental care. Non-steroidal anti-inflammatory drugs are among most widely prescribed analgesics for management of postoperative pain. The analgesic effect of a non-steroidal antiinflammatory drug (NSAID) is related to its ability to inhibit prostaglandin synthesis. Ibuprofen (2-proprionic acid derivate) was discovered in the 1960s as a representative of NSAIDs. It is a peripherally acting analgesic with a potent anti-inflammatory action. An extensive retrospective analysis of randomized clinical trials conducted over the last 40 years demonstrated that ibuprofen is effective in moderate to severe postoperative pain for different indications in dentistry. In comparison to other NSAIDs, ibuprofen is characterized by its efficiency, safety and good tolerance. The aim of this article was to present the most important pharmacological and therapeutic characteristics and side effects of ibuprofen used for postoperative pain treatment in dentistry., Bol koji se javi nakon hirurške intervencije je vrlo česta komplikacija u svakodnevnoj stomatološkoj praksi. U suzbijanju (lečenju) postoperacionog bola najčešće se prepisuju nesteroidni antiinflamatorni lekovi (NSAIL). Njihov analgetski efekat se zasniva, pre svega, na sprečavanju sinteze prostaglandina. Ibuprofen (derivat 2-propionske kiseline) je predstavnik velike grupe NSAIL, a otkriven je 1960. godine. Ovaj analgetik deluje na periferne nervne završetke s izrazitim protivupalnim efektom. Opsežna retrospektivna analiza randomiziranih kliničkih istraživanja u proteklih 40 godina pokazala je da je ibuprofen efikasan u suzbijanju umerenog i izraženog postoperacionog bola kod različitih indikacija. Osim efikasnosti, ibuprofen se odlikuje dobrom podnošljivošću i sigurnošću u poređenju sa drugim NSAIL. Cilj ovog rada bio je da se ukaže na najznačajnije farmakološke i terapeutske odlike, kao i neželjena dejstva ibuprofena u lečenju postoperacionog bola pri različitim indikacijama u stomatologiji.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "The use of ibuprofen in the treatment of postoperative pain in dentistry, Primena ibuprofena u suzbijanju postoperacionog bola u stomatologiji",
volume = "61",
number = "3",
pages = "134-141",
doi = "10.2298/sgs1403134j"
}
Jakovljević, A., Lazić, E., Perunović, N.,& Nedeljković, N.. (2014). The use of ibuprofen in the treatment of postoperative pain in dentistry. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 61(3), 134-141.
https://doi.org/10.2298/sgs1403134j
Jakovljević A, Lazić E, Perunović N, Nedeljković N. The use of ibuprofen in the treatment of postoperative pain in dentistry. in Stomatološki glasnik Srbije. 2014;61(3):134-141.
doi:10.2298/sgs1403134j .
Jakovljević, Aleksandar, Lazić, Emira, Perunović, Neda, Nedeljković, Nenad, "The use of ibuprofen in the treatment of postoperative pain in dentistry" in Stomatološki glasnik Srbije, 61, no. 3 (2014):134-141,
https://doi.org/10.2298/sgs1403134j . .
