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Primena ibuprofena u suzbijanju postoperacionog bola u stomatologiji

dc.creatorJakovljević, Aleksandar
dc.creatorLazić, Emira
dc.creatorPerunović, Neda
dc.creatorNedeljković, Nenad
dc.date.accessioned2020-07-02T12:49:23Z
dc.date.available2020-07-02T12:49:23Z
dc.date.issued2014
dc.identifier.issn0039-1743
dc.identifier.urihttp://smile.stomf.bg.ac.rs/handle/123456789/1873
dc.description.abstractPostoperative pain is common complication after daily dental care. Non-steroidal anti-inflammatory drugs are among most widely prescribed analgesics for management of postoperative pain. The analgesic effect of a non-steroidal antiinflammatory drug (NSAID) is related to its ability to inhibit prostaglandin synthesis. Ibuprofen (2-proprionic acid derivate) was discovered in the 1960s as a representative of NSAIDs. It is a peripherally acting analgesic with a potent anti-inflammatory action. An extensive retrospective analysis of randomized clinical trials conducted over the last 40 years demonstrated that ibuprofen is effective in moderate to severe postoperative pain for different indications in dentistry. In comparison to other NSAIDs, ibuprofen is characterized by its efficiency, safety and good tolerance. The aim of this article was to present the most important pharmacological and therapeutic characteristics and side effects of ibuprofen used for postoperative pain treatment in dentistry.en
dc.description.abstractBol koji se javi nakon hirurške intervencije je vrlo česta komplikacija u svakodnevnoj stomatološkoj praksi. U suzbijanju (lečenju) postoperacionog bola najčešće se prepisuju nesteroidni antiinflamatorni lekovi (NSAIL). Njihov analgetski efekat se zasniva, pre svega, na sprečavanju sinteze prostaglandina. Ibuprofen (derivat 2-propionske kiseline) je predstavnik velike grupe NSAIL, a otkriven je 1960. godine. Ovaj analgetik deluje na periferne nervne završetke s izrazitim protivupalnim efektom. Opsežna retrospektivna analiza randomiziranih kliničkih istraživanja u proteklih 40 godina pokazala je da je ibuprofen efikasan u suzbijanju umerenog i izraženog postoperacionog bola kod različitih indikacija. Osim efikasnosti, ibuprofen se odlikuje dobrom podnošljivošću i sigurnošću u poređenju sa drugim NSAIL. Cilj ovog rada bio je da se ukaže na najznačajnije farmakološke i terapeutske odlike, kao i neželjena dejstva ibuprofena u lečenju postoperacionog bola pri različitim indikacijama u stomatologiji.sr
dc.publisherSrpsko lekarsko društvo - Stomatološka sekcija, Beograd
dc.rightsopenAccess
dc.sourceStomatološki glasnik Srbije
dc.subjectpostoperative painen
dc.subjectnon-steroid anti-inflammatory drugsen
dc.subjectibuprofenen
dc.subjectpostoperacioni bolsr
dc.subjectnesteroidni antiinflamatorni lekovisr
dc.subjectibuprofensr
dc.titleThe use of ibuprofen in the treatment of postoperative pain in dentistryen
dc.titlePrimena ibuprofena u suzbijanju postoperacionog bola u stomatologijisr
dc.typearticle
dc.rights.licenseBY-SA
dcterms.abstractНедељковић, Ненад; Перуновић, Неда; Лазић, Емира; Јаковљевић, Aлександар; Примена ибупрофена у сузбијању постоперационог бола у стоматологији; Примена ибупрофена у сузбијању постоперационог бола у стоматологији;
dc.citation.volume61
dc.citation.issue3
dc.citation.spage134
dc.citation.epage141
dc.citation.other61(3): 134-141
dc.citation.rankM52
dc.identifier.doi10.2298/sgs1403134j
dc.identifier.fulltexthttp://smile.stomf.bg.ac.rs/bitstream/id/552/1868.pdf
dc.identifier.rcubconv_1930
dc.type.versionpublishedVersion


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