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dc.creatorSencanić, Ivan
dc.creatorStamenković, Miroslav
dc.creatorJovanović, Vesna
dc.creatorBabović, Sinisa
dc.creatorJaksić, Vesna
dc.creatorMarković, Petar
dc.date.accessioned2020-07-02T12:51:01Z
dc.date.available2020-07-02T12:51:01Z
dc.date.issued2014
dc.identifier.issn0370-8179
dc.identifier.urihttp://smile.stomf.bg.ac.rs/handle/123456789/1897
dc.description.abstractIntroduction Ultrastructural changes in corneas of patients with diabetes mellitus have been previously described. Objective The aim of this study was to compare central corneal thickness (CDR) values in diabetic patients without retinopathy at the stage of diabetic nonproliferative and proliferative retinopathy and CDR in a control group of healthy subjects. Methods The study included 121 diabetic patients and 125 healthy subjects matched according to gender and age. Each patient underwent ophthalmological examination involving a dilated fundus examination and CDR measurement using the ultrasound pachymeter. The eyes of diabetic patients were classified according to Early Treatment Diabetic Retinopathy Study into three groups: without diabetic retinopathy (NDR), with nonproliferative diabetic retinopathy (NPDR) and a group with proliferative diabetic retinopathy (PDR). Only one eye of each subject was chosen for the study. Results The mean CDR value was significantly higher in the diabetic group (570.52 +/- 31.81 mu m) compared with the control group (541.42 +/- 27.82 mu m). The difference between the two groups was statistically significant (p lt 0.0001). The highest mean CDR value was recorded in the PDR group (585.97 +/- 28.58 mu m), followed by the NPDR group (570.84 +/- 30.27 mu m), whereas the lowest mean CDR value was recorded in the NDR group (559.80 +/- 31.55 mu m). There was a statistically significant difference in CDR between the NDR and PDR groups, as well as between the NPDR and PDR groups (p lt 0.001, p lt 0.05 respectively). No significant difference was recorded between the NDR and NPDR groups (p>0.05). Conclusion CDR of diabetic patients was higher compared to healthy subjects. The highest mean value of CDR was registered in the PDR group, followed by the NPDR and the NDR groups.en
dc.publisherSrpsko lekarsko društvo, Beograd
dc.rightsopenAccess
dc.sourceSrpski arhiv za celokupno lekarstvo
dc.subjectcentral corneal thicknessen
dc.subjectcorneal pachimetryen
dc.subjectdiabetic retinopathyen
dc.titleInfluence of Diabetes Mellitus on Corneal Thicknessen
dc.typearticle
dc.rights.licenseBY-NC
dcterms.abstractМарковић, Петар; Бабовић, Синиса; Јовановић, Весна; Сенцанић, Иван; Стаменковић, Мирослав; Јаксић, Весна;
dc.citation.volume142
dc.citation.issue9-10
dc.citation.spage529
dc.citation.epage534
dc.citation.other142(9-10): 529-534
dc.citation.rankM23
dc.identifier.wos000344306900002
dc.identifier.doi10.2298/SARH1410529S
dc.identifier.pmid25518529
dc.identifier.scopus2-s2.0-84919827547
dc.identifier.fulltexthttp://smile.stomf.bg.ac.rs/bitstream/id/571/1892.pdf
dc.identifier.rcubconv_3209
dc.type.versionpublishedVersion


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