Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization
Апстракт
In this paper, the synthesis and characterization of calcium hydroxyapatite particles, stabilized with poly(ethylene-vinyl acetate) / poly(ethylene-vinyl versatate) (PEVA/PEVV) are presented. The particles were synthesized by two-step hydrothermal method using PEVA/PEVV as a surface-active substance. The structure and crystallinity of the obtained powder were investigated by X-ray diffraction, TEM and HRTEM. The phase identification of hydroxyapatite stabilized with PEVA/PEVV was done by FTIR, while the surface morphology, as well as the size and shape of particles were studied by TEM and AFM. Finally, using MTT and LDH release assays to assess mitochondrial activity and cell membrane integrity, it was confirmed that so synthesized hydroxyapatite powder was not toxic to L929 cells.
Кључне речи:
Hydrothermal synthesis / Hydroxyapatite / Ethylene-vinyl acetate/versatate copolymer / TEM / HRTEMИзвор:
Journal of Optoelectronics & Advanced Materials, 2014, 16, 11-12, 1356-1360Издавач:
- National Institute of Optoelectronics
Финансирање / пројекти:
- Хемијско и структурно дизајнирање наноматеријала за примену у медицини и инжењерству ткива (RS-172026)
Колекције
Институција/група
Stomatološki fakultetTY - JOUR AU - Čolović, Božana AU - Marković, D. AU - Petrović, Milan AU - Jokanović, Vukoman PY - 2014 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1932 AB - In this paper, the synthesis and characterization of calcium hydroxyapatite particles, stabilized with poly(ethylene-vinyl acetate) / poly(ethylene-vinyl versatate) (PEVA/PEVV) are presented. The particles were synthesized by two-step hydrothermal method using PEVA/PEVV as a surface-active substance. The structure and crystallinity of the obtained powder were investigated by X-ray diffraction, TEM and HRTEM. The phase identification of hydroxyapatite stabilized with PEVA/PEVV was done by FTIR, while the surface morphology, as well as the size and shape of particles were studied by TEM and AFM. Finally, using MTT and LDH release assays to assess mitochondrial activity and cell membrane integrity, it was confirmed that so synthesized hydroxyapatite powder was not toxic to L929 cells. PB - National Institute of Optoelectronics T2 - Journal of Optoelectronics & Advanced Materials T1 - Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization VL - 16 IS - 11-12 SP - 1356 EP - 1360 UR - https://hdl.handle.net/21.15107/rcub_vinar_339 ER -
@article{ author = "Čolović, Božana and Marković, D. and Petrović, Milan and Jokanović, Vukoman", year = "2014", abstract = "In this paper, the synthesis and characterization of calcium hydroxyapatite particles, stabilized with poly(ethylene-vinyl acetate) / poly(ethylene-vinyl versatate) (PEVA/PEVV) are presented. The particles were synthesized by two-step hydrothermal method using PEVA/PEVV as a surface-active substance. The structure and crystallinity of the obtained powder were investigated by X-ray diffraction, TEM and HRTEM. The phase identification of hydroxyapatite stabilized with PEVA/PEVV was done by FTIR, while the surface morphology, as well as the size and shape of particles were studied by TEM and AFM. Finally, using MTT and LDH release assays to assess mitochondrial activity and cell membrane integrity, it was confirmed that so synthesized hydroxyapatite powder was not toxic to L929 cells.", publisher = "National Institute of Optoelectronics", journal = "Journal of Optoelectronics & Advanced Materials", title = "Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization", volume = "16", number = "11-12", pages = "1356-1360", url = "https://hdl.handle.net/21.15107/rcub_vinar_339" }
Čolović, B., Marković, D., Petrović, M.,& Jokanović, V.. (2014). Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization. in Journal of Optoelectronics & Advanced Materials National Institute of Optoelectronics., 16(11-12), 1356-1360. https://hdl.handle.net/21.15107/rcub_vinar_339
Čolović B, Marković D, Petrović M, Jokanović V. Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization. in Journal of Optoelectronics & Advanced Materials. 2014;16(11-12):1356-1360. https://hdl.handle.net/21.15107/rcub_vinar_339 .
Čolović, Božana, Marković, D., Petrović, Milan, Jokanović, Vukoman, "Two-step hydrothermal synthesis of nano hydroxyapatite particles and their characterization" in Journal of Optoelectronics & Advanced Materials, 16, no. 11-12 (2014):1356-1360, https://hdl.handle.net/21.15107/rcub_vinar_339 .