The proportion of Europeans descending from Neolithic farmers similar to 10 thousand years ago (KYA) or Palaeolithic hunter-gatherers has been much debated. The male-specific region of the Ychromosome (MSY) has been widely applied to this question, but unbiased estimates of diversity and time depth have been lacking. Here we show that European patrilineages underwent a recent continent-wide expansion. Resequencing of 3.7Mb of MSY DNA in 334 males, comprising 17 European and Middle Eastern populations, defines a phylogeny containing 5,996 single-nucleotide polymorphisms. Dating indicates that three major lineages (I1, R1a and R1b), accounting for 64% of our sample, have very recent coalescent times, ranging between 3.5 and 7.3 KYA. A continuous swathe of 13/17 populations share similar histories featuring a demographic expansion starting similar to 2.1-4.2 KYA. Our results are compatible with ancient MSY DNA data, and contrast with data on mitochondrial DNA, indicating a widespread male...-specific phenomenon that focuses interest on the social structure of Bronze Age Europe.
Netherlands Genomics Initiative/Netherlands Organization for Scientific Research (NWO) within the framework of the Forensic Genomics Consortium NetherlandsNetherlands Organization for Scientific Research (NWO)
TY - JOUR
AU - Batini, Chiara
AU - Hallast, Pille
AU - Zadik, Daniel
AU - Delser, Pierpaolo Maisano
AU - Benazzo, Andrea
AU - Ghirotto, Silvia
AU - Arroyo-Pardo, Eduardo
AU - Cavalleri, Gianpiero L.
AU - de Knijff, Peter
AU - Dupuy, Berit Myhre
AU - Eriksen, Heidi A.
AU - King, Turi E.
AU - Lopez de Munain, Adolfo
AU - Lopez-Parra, Ana M.
AU - Loutradis, Aphrodite
AU - Milašin, Jelena
AU - Novelletto, Andrea
AU - Pamjav, Horolma
AU - Sajantila, Antti
AU - Tolun, Aslihan
AU - Winney, Bruce
AU - Jobling, Mark A.
PY - 2015
UR - https://smile.stomf.bg.ac.rs/handle/123456789/1987
AB - The proportion of Europeans descending from Neolithic farmers similar to 10 thousand years ago (KYA) or Palaeolithic hunter-gatherers has been much debated. The male-specific region of the Ychromosome (MSY) has been widely applied to this question, but unbiased estimates of diversity and time depth have been lacking. Here we show that European patrilineages underwent a recent continent-wide expansion. Resequencing of 3.7Mb of MSY DNA in 334 males, comprising 17 European and Middle Eastern populations, defines a phylogeny containing 5,996 single-nucleotide polymorphisms. Dating indicates that three major lineages (I1, R1a and R1b), accounting for 64% of our sample, have very recent coalescent times, ranging between 3.5 and 7.3 KYA. A continuous swathe of 13/17 populations share similar histories featuring a demographic expansion starting similar to 2.1-4.2 KYA. Our results are compatible with ancient MSY DNA data, and contrast with data on mitochondrial DNA, indicating a widespread male-specific phenomenon that focuses interest on the social structure of Bronze Age Europe.
PB - Nature Publishing Group, London
T2 - Nature Communications
T1 - Large-scale recent expansion of European patrilineages shown by population resequencing
VL - 6
DO - 10.1038/ncomms8152
ER -
@article{
author = "Batini, Chiara and Hallast, Pille and Zadik, Daniel and Delser, Pierpaolo Maisano and Benazzo, Andrea and Ghirotto, Silvia and Arroyo-Pardo, Eduardo and Cavalleri, Gianpiero L. and de Knijff, Peter and Dupuy, Berit Myhre and Eriksen, Heidi A. and King, Turi E. and Lopez de Munain, Adolfo and Lopez-Parra, Ana M. and Loutradis, Aphrodite and Milašin, Jelena and Novelletto, Andrea and Pamjav, Horolma and Sajantila, Antti and Tolun, Aslihan and Winney, Bruce and Jobling, Mark A.",
year = "2015",
abstract = "The proportion of Europeans descending from Neolithic farmers similar to 10 thousand years ago (KYA) or Palaeolithic hunter-gatherers has been much debated. The male-specific region of the Ychromosome (MSY) has been widely applied to this question, but unbiased estimates of diversity and time depth have been lacking. Here we show that European patrilineages underwent a recent continent-wide expansion. Resequencing of 3.7Mb of MSY DNA in 334 males, comprising 17 European and Middle Eastern populations, defines a phylogeny containing 5,996 single-nucleotide polymorphisms. Dating indicates that three major lineages (I1, R1a and R1b), accounting for 64% of our sample, have very recent coalescent times, ranging between 3.5 and 7.3 KYA. A continuous swathe of 13/17 populations share similar histories featuring a demographic expansion starting similar to 2.1-4.2 KYA. Our results are compatible with ancient MSY DNA data, and contrast with data on mitochondrial DNA, indicating a widespread male-specific phenomenon that focuses interest on the social structure of Bronze Age Europe.",
publisher = "Nature Publishing Group, London",
journal = "Nature Communications",
title = "Large-scale recent expansion of European patrilineages shown by population resequencing",
volume = "6",
doi = "10.1038/ncomms8152"
}
Batini, C., Hallast, P., Zadik, D., Delser, P. M., Benazzo, A., Ghirotto, S., Arroyo-Pardo, E., Cavalleri, G. L., de Knijff, P., Dupuy, B. M., Eriksen, H. A., King, T. E., Lopez de Munain, A., Lopez-Parra, A. M., Loutradis, A., Milašin, J., Novelletto, A., Pamjav, H., Sajantila, A., Tolun, A., Winney, B.,& Jobling, M. A.. (2015). Large-scale recent expansion of European patrilineages shown by population resequencing. in Nature Communications
Nature Publishing Group, London., 6.
https://doi.org/10.1038/ncomms8152
Batini C, Hallast P, Zadik D, Delser PM, Benazzo A, Ghirotto S, Arroyo-Pardo E, Cavalleri GL, de Knijff P, Dupuy BM, Eriksen HA, King TE, Lopez de Munain A, Lopez-Parra AM, Loutradis A, Milašin J, Novelletto A, Pamjav H, Sajantila A, Tolun A, Winney B, Jobling MA. Large-scale recent expansion of European patrilineages shown by population resequencing. in Nature Communications. 2015;6.
doi:10.1038/ncomms8152 .
Batini, Chiara, Hallast, Pille, Zadik, Daniel, Delser, Pierpaolo Maisano, Benazzo, Andrea, Ghirotto, Silvia, Arroyo-Pardo, Eduardo, Cavalleri, Gianpiero L., de Knijff, Peter, Dupuy, Berit Myhre, Eriksen, Heidi A., King, Turi E., Lopez de Munain, Adolfo, Lopez-Parra, Ana M., Loutradis, Aphrodite, Milašin, Jelena, Novelletto, Andrea, Pamjav, Horolma, Sajantila, Antti, Tolun, Aslihan, Winney, Bruce, Jobling, Mark A., "Large-scale recent expansion of European patrilineages shown by population resequencing" in Nature Communications, 6 (2015),
https://doi.org/10.1038/ncomms8152 . .
