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NPM1 gene mutations in children with Myelodysplastic syndromes

Jekić, Biljana; Bunjevački, Vera; Dobričić, Valerija; Novaković, Ivana; Milašin, Jelena; Popović, Branka; Damnjanović, Tatjana; Maksimović, Nela; Perović, V.; Luković, Ljiljana (Srpsko biološko društvo, Beograd, i dr., 2011)

Myelodysplastic syndromes (MDS) are rare in children and only a few studies have analyzed their molecular mechanisms. The NPM1 gene encodes for nucleophosmin (NPM) which regulates hematopoiesis. Mutations in exon 12 of the ...