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dc.creatorTodorović, Vladimir S.
dc.creatorVasović, Miroslav
dc.creatorAndrić, Miroslav
dc.creatorTodorović, Ljubomir
dc.creatorKoković, Vladimir
dc.date.accessioned2020-07-02T13:05:08Z
dc.date.available2020-07-02T13:05:08Z
dc.date.issued2016
dc.identifier.issn1698-6946
dc.identifier.urihttp://smile.stomf.bg.ac.rs/handle/123456789/2121
dc.description.abstractBackground: Surgical removal of impacted lower third molars is a common oral surgical procedure, generally followed by moderate to severe postoperative pain. Transdermal drug delivery as a concept offers interesting possibilities for postoperative pain control. The aim of this study was to evaluate the efficacy of transdermal system with fentanyl in relieving pain following impacted lower third molar surgery. Material and Methods: Seventeen patients with bilateral impacted lower third molars were included in this preliminary study. For postoperative pain control, patients randomly received a fentanyl patch plus placebo tablet after the first operation and regular (placebo) patch and an analgesic, after the second operation. Analgesia was evaluated during first 24 hours postoperatively according to patients' reports about time of first pain appearance and additional analgesic consumption. Pain severity was rated using a 10 cm long visual analogue scale (VAS). Results: Intensity of postoperative pain and postoperative analgesic consumption were significantly lower after the Fentanyl Transdermal System (FTS) was applied (p lt 0.05). Duration of postoperative analgesia was significantly higher with FTS when compared to control treatment (p lt 0.05). Conclusions: Based on the results of this preliminary study, transdermal system with fentanyl significantly reduced postoperative pain after third molar surgery.en
dc.publisherMedicina Oral S L, Valencia
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41008/RS//
dc.rightsopenAccess
dc.sourceMedicina Oral Patologia Oral Y Cirugia Bucal
dc.subjectAnalgesiaen
dc.subjectfentanylen
dc.subjecttransdermal administrationen
dc.subjectthird molar surgeryen
dc.subjectacute painen
dc.subjectpostoperative careen
dc.titleEfficacy of fentanyl transdermal patch in pain control after lower third molar surgery: A preliminary studyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractКоковић, Владимир; Тодоровић, Љубомир; Aндрић, Мирослав; Васовић, Мирослав; Тодоровић, Владимир С.;
dc.citation.volume21
dc.citation.issue5
dc.citation.spageE621
dc.citation.epageE625
dc.citation.other21(5): E621-E625
dc.citation.rankM23
dc.identifier.wos000391193600013
dc.identifier.doi10.4317/medoral.21161
dc.identifier.pmid27475691
dc.identifier.scopus2-s2.0-84985914375
dc.identifier.fulltexthttp://smile.stomf.bg.ac.rs/bitstream/id/733/2116.pdf
dc.identifier.rcubconv_3422
dc.type.versionpublishedVersion


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