The aim of this study was to investigate the chemical composition and antifungal activity of four commercial essential oils from the Burseraceae family - two Boswellia carterii Flueck oils, Canarium luzonicum (Blume) A. Gray oil, and Commiphora myrrha (Nees) Engl oil, against most common Candida spp. recovered from the human oral cavity. The essential oil samples were analyzed by GC- FID and GC/MS. The analysis showed that major essential oils' components were. - pinene (23.04 % and 31.84 %), limonene (45.62 %) and curzerene (34.65 %), respectively. Minimum inhibitory (MIC) and minimum fungicidal (MFC) concentrations were determined using a microdilution standardized technique. All tested Candida spp. clinical isolates and ATCC strains showed susceptibility to tested essential oils in a dose dependent manner. The strongest antifungal activity was shown by essential oil of B. carterii, sample 2; the average MIC values ranged from 1.25 to 1.34 mg/ml, and MFC values ranged from 2.50 to 3....75 mg/ml, depending on the fungus. This study supports the possible use of essential oils from the Bursecaceae family in reduction and elimination of Candida spp. populations in patients with oral cavity fungal infections.
TY - JOUR
AU - Nikolić, Miloš
AU - Smiljković, Marija
AU - Marković, Tatjana
AU - Ćirić, Ana
AU - Glamočlija, Jasmina
AU - Marković, Dejan
AU - Soković, Marina
PY - 2016
UR - https://smile.stomf.bg.ac.rs/handle/123456789/2171
AB - The aim of this study was to investigate the chemical composition and antifungal activity of four commercial essential oils from the Burseraceae family - two Boswellia carterii Flueck oils, Canarium luzonicum (Blume) A. Gray oil, and Commiphora myrrha (Nees) Engl oil, against most common Candida spp. recovered from the human oral cavity. The essential oil samples were analyzed by GC- FID and GC/MS. The analysis showed that major essential oils' components were. - pinene (23.04 % and 31.84 %), limonene (45.62 %) and curzerene (34.65 %), respectively. Minimum inhibitory (MIC) and minimum fungicidal (MFC) concentrations were determined using a microdilution standardized technique. All tested Candida spp. clinical isolates and ATCC strains showed susceptibility to tested essential oils in a dose dependent manner. The strongest antifungal activity was shown by essential oil of B. carterii, sample 2; the average MIC values ranged from 1.25 to 1.34 mg/ml, and MFC values ranged from 2.50 to 3.75 mg/ml, depending on the fungus. This study supports the possible use of essential oils from the Bursecaceae family in reduction and elimination of Candida spp. populations in patients with oral cavity fungal infections.
PB - Leibniz Research Centre for Working Environment and Human Factors
T2 - EXCLI Journal
T1 - Sensitivity of clinical isolates of candida to essential oils from burseraceae family
VL - 15
SP - 280
EP - 289
DO - 10.17179/excli2014-621
ER -
@article{
author = "Nikolić, Miloš and Smiljković, Marija and Marković, Tatjana and Ćirić, Ana and Glamočlija, Jasmina and Marković, Dejan and Soković, Marina",
year = "2016",
abstract = "The aim of this study was to investigate the chemical composition and antifungal activity of four commercial essential oils from the Burseraceae family - two Boswellia carterii Flueck oils, Canarium luzonicum (Blume) A. Gray oil, and Commiphora myrrha (Nees) Engl oil, against most common Candida spp. recovered from the human oral cavity. The essential oil samples were analyzed by GC- FID and GC/MS. The analysis showed that major essential oils' components were. - pinene (23.04 % and 31.84 %), limonene (45.62 %) and curzerene (34.65 %), respectively. Minimum inhibitory (MIC) and minimum fungicidal (MFC) concentrations were determined using a microdilution standardized technique. All tested Candida spp. clinical isolates and ATCC strains showed susceptibility to tested essential oils in a dose dependent manner. The strongest antifungal activity was shown by essential oil of B. carterii, sample 2; the average MIC values ranged from 1.25 to 1.34 mg/ml, and MFC values ranged from 2.50 to 3.75 mg/ml, depending on the fungus. This study supports the possible use of essential oils from the Bursecaceae family in reduction and elimination of Candida spp. populations in patients with oral cavity fungal infections.",
publisher = "Leibniz Research Centre for Working Environment and Human Factors",
journal = "EXCLI Journal",
title = "Sensitivity of clinical isolates of candida to essential oils from burseraceae family",
volume = "15",
pages = "280-289",
doi = "10.17179/excli2014-621"
}
Nikolić, M., Smiljković, M., Marković, T., Ćirić, A., Glamočlija, J., Marković, D.,& Soković, M.. (2016). Sensitivity of clinical isolates of candida to essential oils from burseraceae family. in EXCLI Journal
Leibniz Research Centre for Working Environment and Human Factors., 15, 280-289.
https://doi.org/10.17179/excli2014-621
Nikolić M, Smiljković M, Marković T, Ćirić A, Glamočlija J, Marković D, Soković M. Sensitivity of clinical isolates of candida to essential oils from burseraceae family. in EXCLI Journal. 2016;15:280-289.
doi:10.17179/excli2014-621 .
Nikolić, Miloš, Smiljković, Marija, Marković, Tatjana, Ćirić, Ana, Glamočlija, Jasmina, Marković, Dejan, Soković, Marina, "Sensitivity of clinical isolates of candida to essential oils from burseraceae family" in EXCLI Journal, 15 (2016):280-289,
https://doi.org/10.17179/excli2014-621 . .
