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dc.creatorMilić, Marija
dc.creatorBrković, Božidar
dc.creatorKršljak, Elena
dc.creatorStojić, Dragica
dc.date.accessioned2020-07-02T13:08:46Z
dc.date.available2020-07-02T13:08:46Z
dc.date.issued2016
dc.identifier.issn1432-6981
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/2179
dc.description.abstractThe pulpal anesthetic and cardiovascular parameters obtained by 2 % lidocaine with epinephrine (LE; 1:80,000) or clonidine (LC; 15 mcg/ml) were studied in diabetes mellitus (DM) type 2 and healthy volunteers (72), after maxillary infiltration anesthesia. Onset and duration of pulpal anesthesia were measured by electric pulp tester; vasoconstrictive effect of used local anesthetic mixtures by laser Doppler flowmetry (LDF) through pulpal blood flow (PBF); systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were registered by electrocardiogram monitoring. Onset of pulpal anesthesia was shorter for LC than for LE in healthy, while it was not different in diabetic participants; duration of pulpal anesthesia was significantly longer in type 2 diabetic participants, regardless of used anesthetic mixture. Significant reduction of PBF with LE was observed during 45 min in healthy and 60 min in diabetic participants, while with LC such reduction was observed during 45 min in both groups. LE caused a significant increase of SBP in the 5th and 15th minutes in diabetic versus healthy participants, while LC decreased SBP from the 10th to 60th minutes in healthy versus diabetic participants. DM type 2 influences duration of maxillary infiltration anesthesia obtained with LE and LC, and systolic blood pressure during LE anesthesia. The obtained results provide elements for future protocols concerning intraoral local anesthesia in DM type 2 patients.en
dc.publisherSpringer Heidelberg, Heidelberg
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175021/RS//
dc.rightsrestrictedAccess
dc.sourceClinical Oral Investigations
dc.subjectPulpal anesthesiaen
dc.subjectClonidineen
dc.subjectEpinephrineen
dc.subjectDiabetes mellitusen
dc.subjectCardiovascular parametersen
dc.subjectPulpal blood flowen
dc.titleComparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteersen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractБрковић, Божидар; Кршљак, Елена; Стојић, Драгица; Милић, Марија;
dc.citation.volume20
dc.citation.issue6
dc.citation.spage1283
dc.citation.epage1293
dc.citation.other20(6): 1283-1293
dc.citation.rankM21
dc.identifier.wos000379009600020
dc.identifier.doi10.1007/s00784-015-1610-5
dc.identifier.pmid26427866
dc.identifier.scopus2-s2.0-84944526434
dc.type.versionpublishedVersion


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