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dc.creatorJanović, Aleksa
dc.creatorMilovanović, Petar
dc.creatorHahn, Michael
dc.creatorRakočević, Zoran
dc.creatorAmling, Michael
dc.creatorBusse, Bjoern
dc.creatorDimitrijević, Milovan
dc.creatorĐurić, Marija
dc.date.accessioned2020-07-02T13:09:01Z
dc.date.available2020-07-02T13:09:01Z
dc.date.issued2017
dc.identifier.issn1600-4469
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/2183
dc.description.abstractBackground/AimLe Fort lines have traditionally been considered as zones of weakness in the mid-facial skeleton although the structural basis of increased bone fragility at these sites has not yet been investigated. Considering recent findings of occlusal loading-related regional heterogeneity in the mid-facial bone micro-architecture, the aim of this study was to explore whether such heterogeneity in cortical and cancellous bone micro-architecture may contribute to increased fragility at Le Fort fracture sites. Materials and MethodsTwenty-five cortical and thirteen cancellous bone specimens were harvested from a dry skull and analyzed by micro-CT. Specimens were classified into Le Fort or Non-Le Fort groups based on their location in the mid-facial skeleton. ResultsCortical bone along Le Fort lines showed tendencies toward lower thickness (1.50.63 vs 1.75 +/- 0.79; P=.39) and greater porosity (11.48 +/- 5.67 vs 10.28 +/- 5.28; P=.59). A significant difference was detected in the trabecular degree of anisotropy which was higher in cancellous bone from Le Fort fracture sites (2.14 +/- 0.69 vs 1.58 +/- 0.34; P=.02). ConclusionsRegional heterogeneity in cortical bone micro-architecture could not fully explain increased fragility of the mid-facial skeleton at the Le Fort lines. However, regional differences in trabecular bone anisotropy may contribute to increased bone fragility.en
dc.publisherWiley, Hoboken
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45005/RS//
dc.relationSouth-East-Europe Cooperation of University Medical Center Hamburg-Eppendorf
dc.rightsrestrictedAccess
dc.sourceDental Traumatology
dc.subjectboneen
dc.subjectfractureen
dc.subjectLe Forten
dc.subjectmicro-architectureen
dc.subjectmid-facial skeletonen
dc.titleAssociation between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort linesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractAмлинг, Мицхаел; Хахн, Мицхаел; Ракочевић, Зоран; Буссе, Бјоерн; Миловановић, Петар; Ђурић, Марија; Димитријевић, Милован; Јановић, Aлекса;
dc.citation.volume33
dc.citation.issue4
dc.citation.spage300
dc.citation.epage306
dc.citation.other33(4): 300-306
dc.citation.rankM22
dc.identifier.wos000405118400010
dc.identifier.doi10.1111/edt.12333
dc.identifier.pmid28258969
dc.identifier.scopus2-s2.0-85018844318
dc.type.versionpublishedVersion


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