The importance of oral microflora composition in HIV-infected patients is well recognized. However, no studies so far have dealt with age-related changes in periodontal pathogens occurrence in HIV+ individuals. The aim of the present study was to assess and compare temporal changes of bacteria frequency in younger ( lt = 35 years) and older (>= 50 years) HIV-infected and non-infected individuals. Bacterial DNA was isolated from buccal swabs of 30 younger and 30 older subjects in both HIV+ and HIV-groups. By means of PCR the following microorganisms were detected: Aggregatibacter actinomycetemcomitans, Eikenella corrodens, Peptostreptococcus micros, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola. Oral and periodontal examinations were performed in all subjects. The prevalence of microorganisms was significantly higher in HIV+ patients compared to controls, and their distribution showed a notable shift. The decreasing incidence in HIV-subjec...ts was: Pi>Pm>Pg>Aa>Ec>Tf>Td whilst in HIV+ it was: Pi>Pm>Ec>Pg>Tf>Aa>Td. Oral manifestations of HIV infection were more frequent in older compared to younger patients. All measured values of clinical periodontal parameters were significantly higher in older compared to younger HIV+ patients. Ageing in HIV+ subjects is accompanied with a substantial increase and rearrangements of periodontal microflora, potentially aggravating oral and systemic health.
TY - JOUR
AU - Toljić, Boško
AU - Trbovich, Alexander M.
AU - Matić-Petrović, Sanja
AU - Kannosh, Ibrahim
AU - Dragović, Gordana
AU - Jevtović, Đorđe
AU - de Luka, Silvio R.
AU - Ristic-Đurović, Jasna L.
AU - Milašin, Jelena
PY - 2018
UR - http://smile.stomf.bg.ac.rs/handle/123456789/2269
AB - The importance of oral microflora composition in HIV-infected patients is well recognized. However, no studies so far have dealt with age-related changes in periodontal pathogens occurrence in HIV+ individuals. The aim of the present study was to assess and compare temporal changes of bacteria frequency in younger ( lt = 35 years) and older (>= 50 years) HIV-infected and non-infected individuals. Bacterial DNA was isolated from buccal swabs of 30 younger and 30 older subjects in both HIV+ and HIV-groups. By means of PCR the following microorganisms were detected: Aggregatibacter actinomycetemcomitans, Eikenella corrodens, Peptostreptococcus micros, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola. Oral and periodontal examinations were performed in all subjects. The prevalence of microorganisms was significantly higher in HIV+ patients compared to controls, and their distribution showed a notable shift. The decreasing incidence in HIV-subjects was: Pi>Pm>Pg>Aa>Ec>Tf>Td whilst in HIV+ it was: Pi>Pm>Ec>Pg>Tf>Aa>Td. Oral manifestations of HIV infection were more frequent in older compared to younger patients. All measured values of clinical periodontal parameters were significantly higher in older compared to younger HIV+ patients. Ageing in HIV+ subjects is accompanied with a substantial increase and rearrangements of periodontal microflora, potentially aggravating oral and systemic health.
PB - Luigi Ponzio e figlio Editori
C3 - New Microbiologica
T1 - Ageing with HIV - a periodontal perspective
VL - 41
IS - 1
SP - 61
EP - 66
ER -
@article{
author = "Toljić, Boško and Trbovich, Alexander M. and Matić-Petrović, Sanja and Kannosh, Ibrahim and Dragović, Gordana and Jevtović, Đorđe and de Luka, Silvio R. and Ristic-Đurović, Jasna L. and Milašin, Jelena",
year = "2018",
url = "http://smile.stomf.bg.ac.rs/handle/123456789/2269",
abstract = "The importance of oral microflora composition in HIV-infected patients is well recognized. However, no studies so far have dealt with age-related changes in periodontal pathogens occurrence in HIV+ individuals. The aim of the present study was to assess and compare temporal changes of bacteria frequency in younger ( lt = 35 years) and older (>= 50 years) HIV-infected and non-infected individuals. Bacterial DNA was isolated from buccal swabs of 30 younger and 30 older subjects in both HIV+ and HIV-groups. By means of PCR the following microorganisms were detected: Aggregatibacter actinomycetemcomitans, Eikenella corrodens, Peptostreptococcus micros, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola. Oral and periodontal examinations were performed in all subjects. The prevalence of microorganisms was significantly higher in HIV+ patients compared to controls, and their distribution showed a notable shift. The decreasing incidence in HIV-subjects was: Pi>Pm>Pg>Aa>Ec>Tf>Td whilst in HIV+ it was: Pi>Pm>Ec>Pg>Tf>Aa>Td. Oral manifestations of HIV infection were more frequent in older compared to younger patients. All measured values of clinical periodontal parameters were significantly higher in older compared to younger HIV+ patients. Ageing in HIV+ subjects is accompanied with a substantial increase and rearrangements of periodontal microflora, potentially aggravating oral and systemic health.",
publisher = "Luigi Ponzio e figlio Editori",
journal = "New Microbiologica",
title = "Ageing with HIV - a periodontal perspective",
volume = "41",
number = "1",
pages = "61-66"
}
Toljić B, Trbovich AM, Matić-Petrović S, Kannosh I, Dragović G, Jevtović Đ, de Luka SR, Ristic-Đurović JL, Milašin J. Ageing with HIV - a periodontal perspective. New Microbiologica. 2018;41(1):61-66
Toljić, B., Trbovich, A. M., Matić-Petrović, S., Kannosh, I., Dragović, G., Jevtović, Đ., de Luka, S. R., Ristic-Đurović, J. L.,& Milašin, J. (2018). Ageing with HIV - a periodontal perspective.
New MicrobiologicaLuigi Ponzio e figlio Editori., 41(1), 61-66.
Toljić Boško, Trbovich Alexander M., Matić-Petrović Sanja, Kannosh Ibrahim, Dragović Gordana, Jevtović Đorđe, de Luka Silvio R., Ristic-Đurović Jasna L., Milašin Jelena, "Ageing with HIV - a periodontal perspective" 41, no. 1 (2018):61-66
