Background: Burning mouth syndrome (BMS) is an intraoral burning or dysaesthetic sensation, recurring daily for more than two hours during the period longer than 3 months. The objective was to evaluate and analyse the efficacy of serotonin reuptake inhibitor fluoxetine on psychological factors, as well as on pain in participants with BMS. Methods: In a 6-month study, 100 participants with primary and secondary BMS were divided into two groups-fluoxetine and control (placebo) and examined by the dentist and the neurologist. Depression and anxiety were estimated by Hamilton Scale for Depression (HAM-D) and Anxiety (HAM-A) and Beck Depression Inventory (BDI) and the pain intensity by visual analogue scale (VAS). Results: Mean age of the participants was 60.33 in fluoxetine group and 67.4 in control group. Most of the participants were female-74% in the fluoxetine and 78% in the control group. Statistical difference between the fluoxetine and the control group was found in HAM-D results (P... lt .05). Values of other scales and VAS decreased significantly after the therapy in both groups (P lt .05). Conclusions: Our trial results indicate that fluoxetine therapy not only improves the psychological status of participants with BMS but also fluoxetine decreases the intensity of pain in these patients.
TY - JOUR
AU - Zorić, Bojana
AU - Janković, Ljiljana
AU - Kuzmanović-Pfićer, Jovana
AU - Zidverc-Trajković, Jasna
AU - Mijajlović, Milija
AU - Stanimirović, Dragan
PY - 2018
UR - https://smile.stomf.bg.ac.rs/handle/123456789/2288
AB - Background: Burning mouth syndrome (BMS) is an intraoral burning or dysaesthetic sensation, recurring daily for more than two hours during the period longer than 3 months. The objective was to evaluate and analyse the efficacy of serotonin reuptake inhibitor fluoxetine on psychological factors, as well as on pain in participants with BMS. Methods: In a 6-month study, 100 participants with primary and secondary BMS were divided into two groups-fluoxetine and control (placebo) and examined by the dentist and the neurologist. Depression and anxiety were estimated by Hamilton Scale for Depression (HAM-D) and Anxiety (HAM-A) and Beck Depression Inventory (BDI) and the pain intensity by visual analogue scale (VAS). Results: Mean age of the participants was 60.33 in fluoxetine group and 67.4 in control group. Most of the participants were female-74% in the fluoxetine and 78% in the control group. Statistical difference between the fluoxetine and the control group was found in HAM-D results (P lt .05). Values of other scales and VAS decreased significantly after the therapy in both groups (P lt .05). Conclusions: Our trial results indicate that fluoxetine therapy not only improves the psychological status of participants with BMS but also fluoxetine decreases the intensity of pain in these patients.
PB - Wiley, Hoboken
T2 - Gerodontology
T1 - The efficacy of fluoxetine in BMS-A cross-over study
VL - 35
IS - 2
SP - 123
EP - 128
DO - 10.1111/ger.12332
ER -
@article{
author = "Zorić, Bojana and Janković, Ljiljana and Kuzmanović-Pfićer, Jovana and Zidverc-Trajković, Jasna and Mijajlović, Milija and Stanimirović, Dragan",
year = "2018",
abstract = "Background: Burning mouth syndrome (BMS) is an intraoral burning or dysaesthetic sensation, recurring daily for more than two hours during the period longer than 3 months. The objective was to evaluate and analyse the efficacy of serotonin reuptake inhibitor fluoxetine on psychological factors, as well as on pain in participants with BMS. Methods: In a 6-month study, 100 participants with primary and secondary BMS were divided into two groups-fluoxetine and control (placebo) and examined by the dentist and the neurologist. Depression and anxiety were estimated by Hamilton Scale for Depression (HAM-D) and Anxiety (HAM-A) and Beck Depression Inventory (BDI) and the pain intensity by visual analogue scale (VAS). Results: Mean age of the participants was 60.33 in fluoxetine group and 67.4 in control group. Most of the participants were female-74% in the fluoxetine and 78% in the control group. Statistical difference between the fluoxetine and the control group was found in HAM-D results (P lt .05). Values of other scales and VAS decreased significantly after the therapy in both groups (P lt .05). Conclusions: Our trial results indicate that fluoxetine therapy not only improves the psychological status of participants with BMS but also fluoxetine decreases the intensity of pain in these patients.",
publisher = "Wiley, Hoboken",
journal = "Gerodontology",
title = "The efficacy of fluoxetine in BMS-A cross-over study",
volume = "35",
number = "2",
pages = "123-128",
doi = "10.1111/ger.12332"
}
Zorić, B., Janković, L., Kuzmanović-Pfićer, J., Zidverc-Trajković, J., Mijajlović, M.,& Stanimirović, D.. (2018). The efficacy of fluoxetine in BMS-A cross-over study. in Gerodontology
Wiley, Hoboken., 35(2), 123-128.
https://doi.org/10.1111/ger.12332
Zorić B, Janković L, Kuzmanović-Pfićer J, Zidverc-Trajković J, Mijajlović M, Stanimirović D. The efficacy of fluoxetine in BMS-A cross-over study. in Gerodontology. 2018;35(2):123-128.
doi:10.1111/ger.12332 .
Zorić, Bojana, Janković, Ljiljana, Kuzmanović-Pfićer, Jovana, Zidverc-Trajković, Jasna, Mijajlović, Milija, Stanimirović, Dragan, "The efficacy of fluoxetine in BMS-A cross-over study" in Gerodontology, 35, no. 2 (2018):123-128,
https://doi.org/10.1111/ger.12332 . .
