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dc.creatorAšćerić, Radislav
dc.creatorDimković, Nada
dc.creatorTrajković, Goran Z.
dc.creatorRistić, Biljana S.
dc.creatorJanković, Aleksandar N.
dc.creatorĐurić, Petar
dc.creatorIlijevski, Nenad S.
dc.date.accessioned2020-07-02T13:23:20Z
dc.date.available2020-07-02T13:23:20Z
dc.date.issued2019
dc.identifier.issn1471-2369
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/2410
dc.description.abstractBackgroundPeripheral arterial disease (PAD) is common in patients with end-stage renal disease on hemodialysis, but is frequently underdiagnosed. The risk factors for PAD are well known within the general population, but they differ somewhat in hemodialysis patients. This study aimed to determine the prevalence of PAD and its risk factors in patients on hemodialysis.MethodsThis cross-sectional study included 156 hemodialysis patients. Comorbidities and laboratory parameters were analyzed. Following clinical examinations, the ankle-brachial index was measured in all patients. PAD was diagnosed based on the clinical findings, ankle-brachial index lt 0.9, and PAD symptoms.ResultsPAD was present in 55 of 156 (35.3%; 95% CI, 27.7-42.8%) patients. The patients with PAD were significantly older (6710years vs. 62 +/- 11years, p=0.014), more likely to have diabetes mellitus (p=0.022), and anemia (p=0.042), and had significantly lower serum albumin (p=0.005), total cholesterol (p=0.024), and iron (p=0.004) levels, higher glucose (p=0.002) and C-reactive protein (p lt 0.001) levels, and lower dialysis adequacies (p=0.040) than the patients without PAD. Multivariate analysis showed higher C-reactive protein level (odds ratio [OR], 1.03; 95% confidence interval [CI], 1.00-1.06; p=0.030), vascular access by Hickman catheter (OR, 4.66; 95% CI, 1.03-21.0; p=0.045), and symptoms of PAD (OR, 5.20; 95% CI, 2.60-10.4; p lt 0.001) as independent factors associated with PAD in hemodialysis patients.ConclusionThe prevalence of PAD was high among patients with end-stage renal disease on hemodialysis. Symptoms of PAD, higher C-reactive protein levels, and Hickman vascular access were independent predictors of PAD in patients on hemodialysis.en
dc.publisherBMC, LONDON
dc.rightsopenAccess
dc.sourceBMC Nephrology
dc.subjectPeripheral arterial diseaseen
dc.subjectAnkle-brachial indexen
dc.subjectHemodialysisen
dc.subjectC-reactive proteinen
dc.subjectHickman vascular accessen
dc.titlePrevalence, clinical characteristics, and predictors of peripheral arterial disease in hemodialysis patients: a cross-sectional studyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractИлијевски, Ненад С.; Aшћерић, Радислав; Димковић, Нада; Трајковић, Горан З.; Јанковић, Aлександар Н.; Ристић, Биљана С.; Ђурић, Петар;
dc.citation.volume20
dc.citation.rankM22
dc.identifier.wos000477606400003
dc.identifier.doi10.1186/s12882-019-1468-x
dc.identifier.pmid31349820
dc.identifier.scopus2-s2.0-85069973572
dc.identifier.fulltexthttps://smile.stomf.bg.ac.rs/bitstream/id/944/2405.pdf
dc.type.versionpublishedVersion


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