Приказ основних података о документу

dc.creatorKrunić, Jelena
dc.creatorStojanović, Nikola
dc.creatorĐukić, Ljiljana
dc.creatorRoganović, Jelena
dc.creatorPopović, Branka
dc.creatorSimić, Ivana
dc.creatorStojić, Dragica
dc.date.accessioned2020-07-02T13:26:49Z
dc.date.available2020-07-02T13:26:49Z
dc.date.issued2019
dc.identifier.issn1432-6981
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/2465
dc.description.abstractObjectivesTo evaluate local effect of gaseous ozone on bacteria in deep carious lesions after incomplete caries removal, using chlorhexidine as control, and to investigate its effect on pulp vascular endothelial growth factor (VEGF), neuronal nitric oxide synthase (nNOS), and superoxide dismutase (SOD).Materials and methodsAntibacterial effect was evaluated in 48 teeth with diagnosed deep carious lesion. After incomplete caries removal, teeth were randomly allocated into two groups regarding the cavity disinfectant used: ozone (open system) or 2% chlorhexidine. Dentin samples were analyzed for the presence of total bacteria and Lactobacillus spp. by real-time quantitative polymerase chain reaction. For evaluation of ozone effect on dental pulp, 38 intact permanent teeth indicated for pulp removal/tooth extraction were included. After cavity preparation, teeth were randomly allocated into two groups: ozone group and control group. VEGF/nNOS level and SOD activity in dental pulp were determined by enzyme-linked immunosorbent assay and spectrophotometric method, respectively.ResultsOzone application decreased number of total bacteria (p=0.001) and Lactobacillus spp. (p lt 0.001), similarly to chlorhexidine. The VEGF (p lt 0.001) and nNOS (p=0.012) levels in dental pulp after ozone application were higher, while SOD activity was lower (p=0.001) comparing to those in control pulp.ConclusionsAntibacterial effect of ozone on residual bacteria after incomplete caries removal was similar to that of 2% chlorhexidine. Effect of ozone on pulp VEGF, nNOS, and SOD indicated its biocompatibility.Clinical relevanceOzone appears as effective and biocompatible cavity disinfectant in treatment of deep carious lesions by incomplete caries removal technique.en
dc.publisherSpringer Heidelberg, Heidelberg
dc.relationMinistry of Science and Technology, Republic of Srpska, Bosnia and Herzegovina [19/06-020/961-174/12]
dc.rightsrestrictedAccess
dc.sourceClinical Oral Investigations
dc.subjectOzoneen
dc.subjectIncomplete caries removalen
dc.subjectAntibacterial effecten
dc.subjectResidual cariesen
dc.subjectBiocompatibilityen
dc.titleClinical antibacterial effectiveness and biocompatibility of gaseous ozone after incomplete caries removalen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractКрунић, Јелена; Стојић, Драгица; Симић, Ивана; Рогановић, Јелена; Поповић, Бранка; Ђукић, Љиљана; Стојановић, Никола;
dc.citation.volume23
dc.citation.issue2
dc.citation.spage785
dc.citation.epage792
dc.citation.other23(2): 785-792
dc.citation.rankM21
dc.identifier.wos000456712300033
dc.identifier.doi10.1007/s00784-018-2495-x
dc.identifier.pmid29858659
dc.identifier.scopus2-s2.0-85047922533
dc.type.versionpublishedVersion


Документи

Thumbnail

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу