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dc.creatorDragašević, Sanja
dc.creatorSokić-Milutinović, Aleksandra
dc.creatorStojković-Lalošević, Milica
dc.creatorMilovanović, Tamara
dc.creatorĐuranović, Srđan
dc.creatorJovanović, Ivan
dc.creatorRajić, Sanja
dc.creatorStojković, Mirjana
dc.creatorMiličić, Biljana
dc.creatorKmezić, Stefan
dc.creatorOluić, Branislav
dc.creatorAleksić, Marko
dc.creatorPavlović-Marković, Aleksandra
dc.creatorPopović, Dragan
dc.date.accessioned2020-07-02T13:29:27Z
dc.date.available2020-07-02T13:29:27Z
dc.date.issued2020
dc.identifier.issn1687-6121
dc.identifier.urihttp://smile.stomf.bg.ac.rs/handle/123456789/2507
dc.description.abstractBackground and Objectives. Determination of inflammatory bowel disease activity determines further therapeutic approach and follow-up. The aim of our study was to investigate correlation between patients' reported symptoms and endoscopic and histological disease activity. Methods. A cross-sectional study was conducted in consecutive newly diagnosed patients with inflammatory bowel disease in a tertiary care referral center. The initial evaluation included patient-reported outcome for stool frequency subscore and rectal bleeding. Endoscopic activity was determined using the Mayo scoring system for ulcerative colitis and the Simple Endoscopic Score for Crohn's disease. Histopathological activity was assessed using a validated numeric scoring system. Results. We included 159 patients (63 Crohn's disease with colonic involvement and 96 with ulcerative colitis). We found significant correlation between the Mayo endoscopic subscoring system and histology activity in ulcerative colitis, while no correlation was found in patients with Crohn's disease. Patient-reported outcome showed inverse correlation with endoscopic and histological activity in Crohn's disease (rs=-0.67; rs=-0.72), while positive correlation was found in ulcerative colitis (rs=0.84; rs=0.75). Interpretation and Conclusions. Patient-reported outcome is a practical and noninvasive tool for assessment of disease activity in ulcerative colitis patients but not in Crohn's disease.en
dc.publisherHindawi Ltd, London
dc.rightsopenAccess
dc.sourceGastroenterology Research & Practice
dc.titleCorrelation of Patient-Reported Outcome (PRO-2) with Endoscopic and Histological Features in Ulcerative Colitis and Crohn's Disease Patientsen
dc.typearticle
dc.rights.licenseBY
dcterms.abstractAлексић, Марко; Рајић, Сања; Стојковић, Мирјана; Миличић, Биљана; Драгашевић, Сања; Олуић, Бранислав; Сокић-Милутиновић, Aлександра; Стојковић-Лалошевић, Милица; Миловановић, Тамара; Ђурановић, Срђан; Јовановић, Иван; Кмезић, Стефан; Павловић-Марковић, Aлександра; Поповић, Драган;
dc.citation.volume2020
dc.citation.other2020: -
dc.citation.rankM23~
dc.identifier.wos000526946400001
dc.identifier.doi10.1155/2020/2065383
dc.identifier.pmid32328091
dc.identifier.scopus2-s2.0-85083667033
dc.identifier.fulltexthttp://smile.stomf.bg.ac.rs/bitstream/id/1022/2502.pdf
dc.identifier.rcubconv_3706
dc.type.versionpublishedVersion


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