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Comparison of four different suture materials in respect to oral wound healing, microbial colonization, tissue reaction and clinical features-randomized clinical study
Objectives Sutures are the most frequently used medical device for wound closure. They support tissue during the early phase of healing until it regains enough tensile strength. The aim of this study was to compare four different suture materials in terms of the influence on wound healing, microbial adherence, tissue reaction, and relevant clinical parameters which determine their clinical value. Materials and Methods Total number of 32 patients undergoing surgical extraction of four impacted third molars were involved in the study. Clinical parameters were estimated intraoperatively and during the control check-ups. Soft tissue healing around sutures were evaluated on the 3rd and 7th day postoperatively. Microbial colonization was assessed by means of qPCR. Also, histological analysis was done to assess inflammatory reaction. Results Significantly better soft tissue healing was found around monofilament and synthetic sutures compared to multifilament and natural ones respectively. Sof...t tissue healing was significantly better around all sutures on the 7th day than on the 3rd day postoperatively. Conclusions Non-resorbable polypropylene suture showed superior clinical characteristics among all sutures. Moreover, the best healing of soft tissue and the least inflammatory reaction was found around this thread. The poorest soft tissue healing was found around non-resorbable silk suture. This suture elicited strongest inflammatory reaction and showed the greatest microbial adherence affinity compared to alternative sutures.
TY - JOUR
AU - Dragović, Miroslav
AU - Pejović, Marko
AU - Stepić, Jelena
AU - Čolić, Snježana
AU - Dožić, Branko
AU - Dragović, Svetlana
AU - Lazarević, Miloš
AU - Nikolić, Nadja
AU - Milašin, Jelena
AU - Miličić, Biljana
PY - 2020
UR - https://smile.stomf.bg.ac.rs/handle/123456789/2513
AB - Objectives Sutures are the most frequently used medical device for wound closure. They support tissue during the early phase of healing until it regains enough tensile strength. The aim of this study was to compare four different suture materials in terms of the influence on wound healing, microbial adherence, tissue reaction, and relevant clinical parameters which determine their clinical value. Materials and Methods Total number of 32 patients undergoing surgical extraction of four impacted third molars were involved in the study. Clinical parameters were estimated intraoperatively and during the control check-ups. Soft tissue healing around sutures were evaluated on the 3rd and 7th day postoperatively. Microbial colonization was assessed by means of qPCR. Also, histological analysis was done to assess inflammatory reaction. Results Significantly better soft tissue healing was found around monofilament and synthetic sutures compared to multifilament and natural ones respectively. Soft tissue healing was significantly better around all sutures on the 7th day than on the 3rd day postoperatively. Conclusions Non-resorbable polypropylene suture showed superior clinical characteristics among all sutures. Moreover, the best healing of soft tissue and the least inflammatory reaction was found around this thread. The poorest soft tissue healing was found around non-resorbable silk suture. This suture elicited strongest inflammatory reaction and showed the greatest microbial adherence affinity compared to alternative sutures.
PB - Springer Heidelberg, Heidelberg
T2 - Clinical Oral Investigations
T1 - Comparison of four different suture materials in respect to oral wound healing, microbial colonization, tissue reaction and clinical features-randomized clinical study
VL - 24
IS - 4
SP - 1527
EP - 1541
DO - 10.1007/s00784-019-03034-4
ER -
@article{
author = "Dragović, Miroslav and Pejović, Marko and Stepić, Jelena and Čolić, Snježana and Dožić, Branko and Dragović, Svetlana and Lazarević, Miloš and Nikolić, Nadja and Milašin, Jelena and Miličić, Biljana",
year = "2020",
abstract = "Objectives Sutures are the most frequently used medical device for wound closure. They support tissue during the early phase of healing until it regains enough tensile strength. The aim of this study was to compare four different suture materials in terms of the influence on wound healing, microbial adherence, tissue reaction, and relevant clinical parameters which determine their clinical value. Materials and Methods Total number of 32 patients undergoing surgical extraction of four impacted third molars were involved in the study. Clinical parameters were estimated intraoperatively and during the control check-ups. Soft tissue healing around sutures were evaluated on the 3rd and 7th day postoperatively. Microbial colonization was assessed by means of qPCR. Also, histological analysis was done to assess inflammatory reaction. Results Significantly better soft tissue healing was found around monofilament and synthetic sutures compared to multifilament and natural ones respectively. Soft tissue healing was significantly better around all sutures on the 7th day than on the 3rd day postoperatively. Conclusions Non-resorbable polypropylene suture showed superior clinical characteristics among all sutures. Moreover, the best healing of soft tissue and the least inflammatory reaction was found around this thread. The poorest soft tissue healing was found around non-resorbable silk suture. This suture elicited strongest inflammatory reaction and showed the greatest microbial adherence affinity compared to alternative sutures.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Comparison of four different suture materials in respect to oral wound healing, microbial colonization, tissue reaction and clinical features-randomized clinical study",
volume = "24",
number = "4",
pages = "1527-1541",
doi = "10.1007/s00784-019-03034-4"
}
Dragović, M., Pejović, M., Stepić, J., Čolić, S., Dožić, B., Dragović, S., Lazarević, M., Nikolić, N., Milašin, J.,& Miličić, B.. (2020). Comparison of four different suture materials in respect to oral wound healing, microbial colonization, tissue reaction and clinical features-randomized clinical study. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 24(4), 1527-1541.
https://doi.org/10.1007/s00784-019-03034-4
Dragović M, Pejović M, Stepić J, Čolić S, Dožić B, Dragović S, Lazarević M, Nikolić N, Milašin J, Miličić B. Comparison of four different suture materials in respect to oral wound healing, microbial colonization, tissue reaction and clinical features-randomized clinical study. in Clinical Oral Investigations. 2020;24(4):1527-1541.
doi:10.1007/s00784-019-03034-4 .
Dragović, Miroslav, Pejović, Marko, Stepić, Jelena, Čolić, Snježana, Dožić, Branko, Dragović, Svetlana, Lazarević, Miloš, Nikolić, Nadja, Milašin, Jelena, Miličić, Biljana, "Comparison of four different suture materials in respect to oral wound healing, microbial colonization, tissue reaction and clinical features-randomized clinical study" in Clinical Oral Investigations, 24, no. 4 (2020):1527-1541,
https://doi.org/10.1007/s00784-019-03034-4 . .
