Comparison of four different suture materials in respect to oral wound healing, microbial colonization, tissue reaction and clinical features-randomized clinical study
Само за регистроване кориснике
2020
Аутори
Dragović, Miroslav
Pejović, Marko
Stepić, Jelena
Čolić, Snježana
Dožić, Branko

Dragović, Svetlana
Lazarević, Miloš

Nikolić, Nađa

Milašin, Jelena

Miličić, Biljana

Чланак у часопису (Објављена верзија)

Метаподаци
Приказ свих података о документуАпстракт
Objectives Sutures are the most frequently used medical device for wound closure. They support tissue during the early phase of healing until it regains enough tensile strength. The aim of this study was to compare four different suture materials in terms of the influence on wound healing, microbial adherence, tissue reaction, and relevant clinical parameters which determine their clinical value. Materials and Methods Total number of 32 patients undergoing surgical extraction of four impacted third molars were involved in the study. Clinical parameters were estimated intraoperatively and during the control check-ups. Soft tissue healing around sutures were evaluated on the 3rd and 7th day postoperatively. Microbial colonization was assessed by means of qPCR. Also, histological analysis was done to assess inflammatory reaction. Results Significantly better soft tissue healing was found around monofilament and synthetic sutures compared to multifilament and natural ones respectively. Sof...t tissue healing was significantly better around all sutures on the 7th day than on the 3rd day postoperatively. Conclusions Non-resorbable polypropylene suture showed superior clinical characteristics among all sutures. Moreover, the best healing of soft tissue and the least inflammatory reaction was found around this thread. The poorest soft tissue healing was found around non-resorbable silk suture. This suture elicited strongest inflammatory reaction and showed the greatest microbial adherence affinity compared to alternative sutures.
Кључне речи:
Sutures / Microbial adherence / Monofilament / Soft tissue healing / Inflammatory reactions / Oral surgeryИзвор:
Clinical Oral Investigations, 2020, 24, 4, 1527-1541Издавач:
- Springer Heidelberg, Heidelberg
Пројекти:
DOI: 10.1007/s00784-019-03034-4
ISSN: 1432-6981
PubMed: 31342245