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dc.creatorDragović, Miroslav
dc.creatorPejović, Marko
dc.creatorStepić, Jelena
dc.creatorČolić, Snježana
dc.creatorDožić, Branko
dc.creatorDragović, Svetlana
dc.creatorLazarević, Miloš
dc.creatorNikolić, Nađa
dc.creatorMilašin, Jelena
dc.creatorMiličić, Biljana
dc.date.accessioned2020-07-02T13:29:50Z
dc.date.available2020-07-02T13:29:50Z
dc.date.issued2020
dc.identifier.issn1432-6981
dc.identifier.urihttp://smile.stomf.bg.ac.rs/handle/123456789/2513
dc.description.abstractObjectives Sutures are the most frequently used medical device for wound closure. They support tissue during the early phase of healing until it regains enough tensile strength. The aim of this study was to compare four different suture materials in terms of the influence on wound healing, microbial adherence, tissue reaction, and relevant clinical parameters which determine their clinical value. Materials and Methods Total number of 32 patients undergoing surgical extraction of four impacted third molars were involved in the study. Clinical parameters were estimated intraoperatively and during the control check-ups. Soft tissue healing around sutures were evaluated on the 3rd and 7th day postoperatively. Microbial colonization was assessed by means of qPCR. Also, histological analysis was done to assess inflammatory reaction. Results Significantly better soft tissue healing was found around monofilament and synthetic sutures compared to multifilament and natural ones respectively. Soft tissue healing was significantly better around all sutures on the 7th day than on the 3rd day postoperatively. Conclusions Non-resorbable polypropylene suture showed superior clinical characteristics among all sutures. Moreover, the best healing of soft tissue and the least inflammatory reaction was found around this thread. The poorest soft tissue healing was found around non-resorbable silk suture. This suture elicited strongest inflammatory reaction and showed the greatest microbial adherence affinity compared to alternative sutures.en
dc.publisherSpringer Heidelberg, Heidelberg
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175075/RS//
dc.rightsrestrictedAccess
dc.sourceClinical Oral Investigations
dc.subjectSuturesen
dc.subjectMicrobial adherenceen
dc.subjectMonofilamenten
dc.subjectSoft tissue healingen
dc.subjectInflammatory reactionsen
dc.subjectOral surgeryen
dc.titleComparison of four different suture materials in respect to oral wound healing, microbial colonization, tissue reaction and clinical features-randomized clinical studyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractДраговић, Мирослав; Драговић, Светлана; Чолић, Сњежана; Степић, Јелена; Пејовић, Марко; Миличић, Биљана; Милашин, Јелена; Дожић, Бранко; Николић, Нађа; Лазаревић, Милош;
dc.citation.volume24
dc.citation.issue4
dc.citation.spage1527
dc.citation.epage1541
dc.citation.other24(4): 1527-1541
dc.citation.rankM21~
dc.identifier.wos000522668100018
dc.identifier.doi10.1007/s00784-019-03034-4
dc.identifier.pmid31342245
dc.identifier.scopus2-s2.0-85069688911
dc.identifier.rcubconv_3698
dc.type.versionpublishedVersion


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