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dc.creatorPinkney, T.
dc.creatorBattersby, N.
dc.creatorBhangu, A.
dc.creatorChaudhri, S.
dc.creatorEl-Hussuna, A.
dc.creatorFrasson, M.
dc.creatorNepogodiev, D.
dc.creatorSingh, B.
dc.creatorKovačević, Bojan
dc.creator(i jos puno autora)
dc.date.accessioned2020-07-10T10:40:43Z
dc.date.available2018-02-13
dc.date.issued2017
dc.identifier.issn1462-8910
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/2523
dc.description.abstractAim The anastomosis technique used following right-sided colonic resection is widely variable and may affect patient outcome. This study aimed to assess the association between leak and anastomosis technique (stapled vs handsewn). Method This was a prospective, multicentre, international audit including patients undergoing elective or emergency right hemicolectomy or ileo-caecal resection operations over a 2-month period in early 2015. The primary outcome measure was the presence of anastomotic leak within 30 days of surgery, determined using a prespecified definition. Mixed effects logistic regression models were used to assess the association between leak and anastomosis method, adjusting for patient, disease and operative cofactors, with centre included as a random-effect variable. Results This study included 3208 patients, of whom 78.4% (n = 2515) underwent surgery for malignancy and 11.7% (n = 375) underwent surgery for Crohn's disease. An anastomosis was performed in 94.8% (n = 3041) of patients, which was handsewn in 38.9% (n = 1183) and stapled in 61.1% (n = 1858). Patients undergoing hand-sewn anastomosis were more likely to be emergency admissions (20.5% handsewn vs 12.9% stapled) and to undergo open surgery (54.7% handsewn vs 36.6% stapled). The overall anastomotic leak rate was 8.1% (245/3041), which was similar following handsewn (7.4%) and stapled (8.5%) techniques (P = 0.3). After adjustment for cofactors, the odds of a leak were higher for stapled anastomosis (adjusted OR = 1.43; 95% CI: 1.04-1.95; P = 0.03). Conclusion Despite being used in lower-risk patients, stapled anastomosis was associated with an increased anastomotic leak rate in this observational study. Further research is needed to define patient groups in whom a stapled anastomosis is safe.en
dc.publisherWiley, Hoboken
dc.rightsembargoedAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.sourceColorectal Disease
dc.subjectAnastomotic leaken
dc.subjectcolorectal canceren
dc.subjectCrohn's diseaseen
dc.subjectepidemiologyen
dc.subjectinternationalen
dc.titleRelationship between method of anastomosis and anastomotic failure after right hemicolectomy and ileo-caecal resection: an international snapshot auditen
dc.typearticle
dc.rights.licenseBY-NC
dcterms.abstractКовачевић, Бојан; Пинкнеy, Т.; Баттерсбy, Н.; Бхангу, A.; Цхаудхри, С.; Ел-Хуссуна, A.; Фрассон, М.; Непогодиев, Д.; Сингх, Б.; (и јос пуно аутора);
dc.citation.volume19
dc.citation.issue8
dc.citation.spageO296
dc.citation.epageO311
dc.citation.rankM21
dc.description.otherThis is the peer-reviewed version of the article: Pinkney, T.; Battersby, N.; Bhangu, A.; Chaudhri, S.; El-Hussuna, A.; Frasson, M.; Nepogodiev, D.; Singh, B.; Kovačević, B.; Autora), (i Jos Puno. Relationship between Method of Anastomosis and Anastomotic Failure after Right Hemicolectomy and Ileo-Caecal Resection: An International Snapshot Audit. Colorectal Disease 2017, 19 (8), O296–O311. [https://doi.org/10.1111/codi.13646]
dc.identifier.wos000406961000003
dc.identifier.doi10.1111/codi.13646
dc.identifier.pmid28263043
dc.identifier.scopus2-s2.0-85026746396
dc.identifier.fulltexthttps://smile.stomf.bg.ac.rs/bitstream/id/5239/The_relationship_between_acc_2017.pdf
dc.type.versionacceptedVersion


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