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Relationship between method of anastomosis and anastomotic failure after right hemicolectomy and ileo-caecal resection: an international snapshot audit
dc.creator | Pinkney, T. | |
dc.creator | Battersby, N. | |
dc.creator | Bhangu, A. | |
dc.creator | Chaudhri, S. | |
dc.creator | El-Hussuna, A. | |
dc.creator | Frasson, M. | |
dc.creator | Nepogodiev, D. | |
dc.creator | Singh, B. | |
dc.creator | Kovačević, Bojan | |
dc.creator | (i jos puno autora) | |
dc.date.accessioned | 2020-07-10T10:40:43Z | |
dc.date.available | 2018-02-13 | |
dc.date.issued | 2017 | |
dc.identifier.issn | 1462-8910 | |
dc.identifier.uri | https://smile.stomf.bg.ac.rs/handle/123456789/2523 | |
dc.description.abstract | Aim The anastomosis technique used following right-sided colonic resection is widely variable and may affect patient outcome. This study aimed to assess the association between leak and anastomosis technique (stapled vs handsewn). Method This was a prospective, multicentre, international audit including patients undergoing elective or emergency right hemicolectomy or ileo-caecal resection operations over a 2-month period in early 2015. The primary outcome measure was the presence of anastomotic leak within 30 days of surgery, determined using a prespecified definition. Mixed effects logistic regression models were used to assess the association between leak and anastomosis method, adjusting for patient, disease and operative cofactors, with centre included as a random-effect variable. Results This study included 3208 patients, of whom 78.4% (n = 2515) underwent surgery for malignancy and 11.7% (n = 375) underwent surgery for Crohn's disease. An anastomosis was performed in 94.8% (n = 3041) of patients, which was handsewn in 38.9% (n = 1183) and stapled in 61.1% (n = 1858). Patients undergoing hand-sewn anastomosis were more likely to be emergency admissions (20.5% handsewn vs 12.9% stapled) and to undergo open surgery (54.7% handsewn vs 36.6% stapled). The overall anastomotic leak rate was 8.1% (245/3041), which was similar following handsewn (7.4%) and stapled (8.5%) techniques (P = 0.3). After adjustment for cofactors, the odds of a leak were higher for stapled anastomosis (adjusted OR = 1.43; 95% CI: 1.04-1.95; P = 0.03). Conclusion Despite being used in lower-risk patients, stapled anastomosis was associated with an increased anastomotic leak rate in this observational study. Further research is needed to define patient groups in whom a stapled anastomosis is safe. | en |
dc.publisher | Wiley, Hoboken | |
dc.rights | embargoedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
dc.source | Colorectal Disease | |
dc.subject | Anastomotic leak | en |
dc.subject | colorectal cancer | en |
dc.subject | Crohn's disease | en |
dc.subject | epidemiology | en |
dc.subject | international | en |
dc.title | Relationship between method of anastomosis and anastomotic failure after right hemicolectomy and ileo-caecal resection: an international snapshot audit | en |
dc.type | article | |
dc.rights.license | BY-NC | |
dcterms.abstract | Ковачевић, Бојан; Пинкнеy, Т.; Баттерсбy, Н.; Бхангу, A.; Цхаудхри, С.; Ел-Хуссуна, A.; Фрассон, М.; Непогодиев, Д.; Сингх, Б.; (и јос пуно аутора); | |
dc.citation.volume | 19 | |
dc.citation.issue | 8 | |
dc.citation.spage | O296 | |
dc.citation.epage | O311 | |
dc.citation.rank | M21 | |
dc.description.other | This is the peer-reviewed version of the article: Pinkney, T.; Battersby, N.; Bhangu, A.; Chaudhri, S.; El-Hussuna, A.; Frasson, M.; Nepogodiev, D.; Singh, B.; Kovačević, B.; Autora), (i Jos Puno. Relationship between Method of Anastomosis and Anastomotic Failure after Right Hemicolectomy and Ileo-Caecal Resection: An International Snapshot Audit. Colorectal Disease 2017, 19 (8), O296–O311. [https://doi.org/10.1111/codi.13646] | |
dc.identifier.wos | 000406961000003 | |
dc.identifier.doi | 10.1111/codi.13646 | |
dc.identifier.pmid | 28263043 | |
dc.identifier.scopus | 2-s2.0-85026746396 | |
dc.identifier.fulltext | https://smile.stomf.bg.ac.rs/bitstream/id/5239/The_relationship_between_acc_2017.pdf | |
dc.type.version | acceptedVersion |