Приказ основних података о документу

dc.creatorŠljivančanin Jakovljević, Tamara
dc.creatorJaćimović, Jelena
dc.creatorNikolić, Nadja
dc.creatorMilašin, Jelena
dc.date.accessioned2021-03-29T22:32:56Z
dc.date.available2021-03-29T22:32:56Z
dc.date.issued2020
dc.identifier.issn1046-7408
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/2569
dc.description.abstractInsufficient response to oxidative stress in placenta is proposed as a contributing factor for preeclampsia (PE) development. Glutathione S-transferases (GST) have significant role in detoxification processes. Conflicting results were published by several research groups regarding GST T1 and GST M1 deletion polymorphism as risk factors for PE. The aim of the present meta-analysis was to get a better understanding of the impact of these polymorphisms in preeclampsia development. To identify relevant case-control studies, the author team searched Clarivate Analytics Web of Science, Scopus, PubMed, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, major subject journals, and gray literature. Pooled odds ratios and 95% confidence intervals for GST M1 and GST T1 deletion polymorphism and preeclampsia were derived from random effects models. This meta-analysis included 10 eligible studies. The pooled analyses showed no association between GST M1/GST T1 deletion polymorphisms and susceptibility to PE. Even though high heterogeneity was founded among results for GST M1 and double null genotypes, Egger's and Begg's tests (0.17 and 0.18, respectively) revealed no statistical evidence of publication bias among included studies. The present updated systematic review and meta-analysis found no association between GST M1 and GST T1 deletion polymorphism and PE risk.sr
dc.language.isoensr
dc.publisherWileysr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175075/RS//sr
dc.rightsrestrictedAccesssr
dc.sourceAmerican Journal of Reproductive Immunologysr
dc.subjectgenesr
dc.subjectglutathione S-transferase M1sr
dc.subjectglutathione S-transferase T1sr
dc.subjectmeta-analysissr
dc.subjectpolymorphismsr
dc.subjectpreeclampsiasr
dc.titleLack of association between glutathione S-transferase M1 and T1 gene polymorphisms and susceptibility to preeclampsia: An updated systematic review and meta-analysissr
dc.typearticlesr
dc.rights.licenseARRsr
dcterms.abstractНиколић, Надја; Милашин, Јелена; Шљиванчанин Јаковљевић, Тамара; Јаћимовић, Јелена;
dc.citation.volume84
dc.citation.issue6
dc.citation.spagee13303
dc.identifier.wos000554354000001
dc.identifier.doi10.1111/aji.13303
dc.identifier.pmid32658338
dc.identifier.scopus2-s2.0-85088800277
dc.type.versionpublishedVersionsr


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Приказ основних података о документу